Spyre Therapeutics (SYRE) Free Cash Flow (2015 - 2026)
Spyre Therapeutics' Free Cash Flow came in at -$69.88 million for Q2 2026, compared with -$46.56 million a year earlier.
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Analysis
Spyre Therapeutics (SYRE) Free Cash Flow (2015 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Spyre Therapeutics reported Free Cash Flow of -$208.94 million; for FY2025, it was -$169.25 million.
- Going back by year, Free Cash Flow was -$157.41 million in FY2024, -$99.91 million in FY2023, -$80.18 million in FY2022 and -$54.29 million in FY2021.
- The Q2 2026 figure represents the lowest quarterly Free Cash Flow in data going back to Q1 2015.
- Business Quant data shows SYRE's Free Cash Flow at -$57.37 million (Q1 2026), -$44.58 million (Q4 2025) and -$37.12 million (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,082.65 Bn | 1,051.23 Bn | 19.71 Bn | 7.76 Bn |
| 2 | Johnson & Johnson | 623.68 Bn | 542.21 Bn | 17.26 Bn | 7.30 Bn |
| 3 | AbbVie | 459.43 Bn | 432.59 Bn | 12.70 Bn | 3.11 Bn |
| 4 | Merck | 354.80 Bn | 309.23 Bn | 12.21 Bn | 4.48 Bn |
| 5 | Novartis Ag | 269.16 Bn | 225.03 Bn | 11.24 Bn | 6.20 Bn |
| 6 | Astrazeneca | 244.40 Bn | 217.97 Bn | 12.86 Bn | 5.34 Bn |
| 7 | Amgen | 220.17 Bn | 175.57 Bn | 7.24 Bn | 3.49 Bn |
| 8 | Gilead Sciences | 183.05 Bn | 157.16 Bn | 6.22 Bn | 3.43 Bn |
| 9 | Pfizer | 160.27 Bn | 107.22 Bn | 10.94 Bn | 302.00 Mn |
| 10 | Spyre Therapeutics | 7.92 Bn | 7.92 Bn | - | -69.88 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -69.88 Mn |
| Mar 31, 2026 | -57.37 Mn |
| Dec 31, 2025 | -44.58 Mn |
| Sep 30, 2025 | -37.12 Mn |
| Jun 30, 2025 | -46.56 Mn |
| Mar 31, 2025 | -40.99 Mn |
| Dec 31, 2024 | -37.20 Mn |
| Sep 30, 2024 | -29.42 Mn |
| Jun 30, 2024 | -62.25 Mn |
| Mar 31, 2024 | -28.54 Mn |
| Dec 31, 2023 | -31.04 Mn |
| Sep 30, 2023 | -34.60 Mn |
| Jun 30, 2023 | -16.64 Mn |
| Mar 31, 2023 | -17.63 Mn |
| Dec 31, 2022 | -18.14 Mn |
| Sep 30, 2022 | -15.07 Mn |
| Jun 30, 2022 | -20.67 Mn |
| Mar 31, 2022 | -26.30 Mn |
| Dec 31, 2021 | -19.27 Mn |
| Sep 30, 2021 | -17.09 Mn |
API Access
Spyre Therapeutics Free Cash Flow API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=free-cash-flow&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "free-cash-flow", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=free-cash-flow&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();