Spyre Therapeutics SYRE
NASDAQ SYRE
$89.03 +4.31 (+5.09%)
At close: Sep 30, 2026 · 4:00 PM EDT

Spyre Therapeutics (SYRE) EBIT Margin (2017 - 2023)

Updated

Spyre Therapeutics (SYRE) recorded EBIT Margin of -27347.97% in FY2023, down 23707.74 percentage points from -3640.23% in FY2022.

Analysis

Spyre Therapeutics (SYRE) EBIT Margin (2017 - 2023) Analysis & Trends

Starting with FY2016, Spyre Therapeutics' EBIT Margin history includes 6 years.

  • Annual EBIT Margin has a five-year change of -26182.25 percentage points (FY2018 to FY2023).
  • The FY2023 figure is the lowest annual EBIT Margin in data going back to FY2016.
  • Per Business Quant data, SYRE's EBIT Margin was -3640.23% in FY2022 (-3289.90 pp) and -350.33% in FY2021.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Johnson & Johnson 638.12 Bn 556.64 Bn 17.26 Bn 28.21%
2 AbbVie 462.60 Bn 435.75 Bn 12.70 Bn 37.86%
3 Merck 358.70 Bn 313.13 Bn 12.21 Bn -3.52%
4 Novartis Ag 272.16 Bn 228.03 Bn 11.24 Bn 32.97%
5 Astrazeneca 250.36 Bn 223.92 Bn 12.86 Bn 20.57%
6 Amgen 227.87 Bn 183.27 Bn 7.24 Bn 34.95%
7 Gilead Sciences 184.97 Bn 159.08 Bn 6.22 Bn -133.21%
8 Pfizer 162.61 Bn 109.56 Bn 10.94 Bn 28.37%
9 Vertex Pharmaceuticals 132.45 Bn 104.46 Bn 2.84 Bn 37.40%
10 Spyre Therapeutics 7.84 Bn 7.84 Bn - -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2023 -23,146.22%
Mar 31, 2023 -9,497.98%
Dec 31, 2022 -11,405.95%
Sep 30, 2022 -10,778.74%
Jun 30, 2022 -3,587.68%
Mar 31, 2022 -1,794.49%
Dec 31, 2021 -560.98%
Sep 30, 2021 -1,450.54%
Jun 30, 2021 -48.96%
Jun 30, 2018 -406.64%
Mar 31, 2018 -546.03%
Dec 31, 2017 -446.86%
Sep 30, 2017 -634.26%
Jun 30, 2017 -454.36%
Mar 31, 2017 -644.70%
API Access

Spyre Therapeutics EBIT Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=ebit-margin&ticker=SYRE&period=max&api_key=YOUR_API_KEY