Spyre Therapeutics SYRE
NASDAQ SYRE
$92.65 -0.30 (-0.32%)
As of: Oct 22, 2026 · 10:43 AM EDT

Spyre Therapeutics (SYRE) EBIT Margin (2017 - 2023)

Updated

Spyre Therapeutics (SYRE) recorded EBIT Margin of -27347.97% in FY2023, down 23707.74 percentage points from -3640.23% in FY2022.

Analysis

Spyre Therapeutics (SYRE) EBIT Margin (2017 - 2023) Analysis & Trends

Starting with FY2016, Spyre Therapeutics' EBIT Margin history includes 6 years.

  • Annual EBIT Margin has a five-year change of -26182.25 percentage points (FY2018 to FY2023).
  • The FY2023 figure is the lowest annual EBIT Margin in data going back to FY2016.
  • Per Business Quant data, SYRE's EBIT Margin was -3640.23% in FY2022 (-3289.90 pp) and -350.33% in FY2021.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Eli Lilly 1,166.12 Bn 1,134.70 Bn 19.71 Bn 51.16%
2 Johnson & Johnson 634.67 Bn 553.20 Bn 17.26 Bn 28.21%
3 AbbVie 503.03 Bn 476.14 Bn 12.70 Bn 37.86%
4 Merck 377.66 Bn 332.04 Bn 12.21 Bn -3.52%
5 Novartis Ag 303.82 Bn 267.81 Bn 11.24 Bn 32.97%
6 Astrazeneca 266.80 Bn 240.49 Bn 12.86 Bn 20.57%
7 Amgen 240.87 Bn 196.27 Bn 7.24 Bn 34.95%
8 Gilead Sciences 193.45 Bn 167.65 Bn 6.22 Bn -133.21%
9 Pfizer 172.20 Bn 118.84 Bn 10.94 Bn 28.37%
10 Spyre Therapeutics 7.83 Bn 4.70 Bn - -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2023 -23,146.22%
Mar 31, 2023 -9,497.98%
Dec 31, 2022 -11,405.95%
Sep 30, 2022 -10,778.74%
Jun 30, 2022 -3,587.68%
Mar 31, 2022 -1,794.49%
Dec 31, 2021 -560.98%
Sep 30, 2021 -1,450.54%
Jun 30, 2021 -48.96%
Jun 30, 2018 -406.64%
Mar 31, 2018 -546.03%
Dec 31, 2017 -446.86%
Sep 30, 2017 -634.26%
Jun 30, 2017 -454.36%
Mar 31, 2017 -644.70%
API Access

Spyre Therapeutics EBIT Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=ebit-margin&ticker=SYRE&period=max&api_key=YOUR_API_KEY