Spyre Therapeutics (SYRE) Shares Outstanding (Weighted Average) (2015 - 2026)

Spyre Therapeutics (SYRE) reported Shares Outstanding (Weighted Average) of $78.5 million for Q1 2026, up 30.34% on a YoY basis from $60.3 million in Q1 2025, and up 22.62% quarter-over-quarter from $64.1 million in Q4 2025.

Spyre Therapeutics (SYRE) Shares Outstanding (Weighted Average) (2015 - 2026) Analysis & Trends

Spyre Therapeutics has reported Shares Outstanding (Weighted Average) for 12 years, with the latest figure at $78.5 million in Q1 2026.

  • For the quarter ending Q1 2026, Shares Outstanding (Weighted Average) rose 30.34% year-over-year to $78.5 million; the trailing twelve-month figure through Mar 2026 stood at $78.5 million (up 30.34% YoY), and the FY2025 full-year result was $64.1 million, up 75076.56% from the prior year.
  • Shares Outstanding (Weighted Average) for Q1 2026 stood at $78.5 million, up from $64.1 million in the prior quarter.
  • The five-year high for Shares Outstanding (Weighted Average) was $78.5 million in Q1 2026, with the low at $16667.0 in Q3 2025.
  • Historically, Shares Outstanding (Weighted Average) has averaged $31.6 million across 5 years, with a median of $21.6 million in 2023.
  • The largest YoY upside for Shares Outstanding (Weighted Average) was 75076.56% in 2025 against a maximum downside of 99.96% in 2025.
  • Spyre Therapeutics' Shares Outstanding (Weighted Average) stood at $3.2 million in 2022, then jumped by 114.0% to $6.9 million in 2023, then plunged by 98.76% to $85208.0 in 2024, then surged by 75076.56% to $64.1 million in 2025, then increased by 22.62% to $78.5 million in 2026.
  • The last three Shares Outstanding (Weighted Average) figures came in at $78.5 million (Q1 2026), $64.1 million (Q4 2025), and $16667.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares (Weighted Avg.) (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 185,491.37 Bn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 400.00 Bn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 4,489.46 Bn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 100.00 Bn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 417.01 Bn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 118.76 Bn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 68.88 Bn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 254.10 Mn
9 Abivax 91.96 Bn 91.96 Bn - 928.40 Mn
10 Spyre Therapeutics 6.95 Bn 6.95 Bn - 78.55 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 78.55 Mn
Dec 31, 2025 64.06 Mn
Sep 30, 2025 16,667.00
Jun 30, 2025 60.30 Mn
Mar 31, 2025 60.27 Mn
Dec 31, 2024 85,208.00
Sep 30, 2024 44.15 Mn
Jun 30, 2024 154,503.00
Mar 31, 2024 36.26 Mn
Dec 31, 2023 6.90 Mn
Sep 30, 2023 4.29 Mn
Jun 30, 2023 3.82 Mn
Mar 31, 2023 3.77 Mn
Sep 30, 2022 3.22 Mn
Jun 30, 2022 73.65 Mn
Mar 31, 2022 66.00 Mn
Dec 31, 2021 2.63 Mn
Sep 30, 2021 12.86 Mn
Jun 30, 2021 65.63 Mn
Mar 31, 2021 65.60 Mn