Spyre Therapeutics (SYRE) Other Operating Expenses (2023 - 2026)
Spyre Therapeutics' Other Operating Expenses came in at $89.17 million for Q3 2026, up 97.1% from $45.25 million a year earlier and up 249.6% from the prior quarter.
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Analysis
Spyre Therapeutics (SYRE) Other Operating Expenses (2023 - 2026) Analysis & Trends
Over the trailing twelve months to Sep 30, 2026, Spyre Therapeutics reported Other Operating Expenses of $189.72 million, up 13.3% year-over-year; for FY2025, it was $161.65 million, down 0.7% from FY2024.
- Other Operating Expenses carries a five-year compound annual growth rate of 22.1% (FY2020 to FY2025).
- Going back by year, Other Operating Expenses was $162.79 million in FY2024 (-19.9%), $203.24 million in FY2023 (+247.0%), $58.58 million in FY2022 (+2.6%) and $57.07 million in FY2021 (-4.3%).
- The Q3 2026 figure represents the highest quarterly Other Operating Expenses since Q2 2023.
- Year-over-year, Other Operating Expenses increased in four of the last eight quarters, with growth averaging 14.3%.
- The fastest year-over-year change in Other Operating Expenses over five years came in Q2 2023 (growth of 861.9%), and the weakest in Q2 2024 (a decline of 77.9%).
- Business Quant data shows SYRE's Other Operating Expenses at $25.5 million (Q2 2026), $30.41 million (Q1 2026) and $44.64 million (Q4 2025) in the three quarters before Q3 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn |
| 10 | Spyre Therapeutics | 9.40 Bn | 5.68 Bn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -40.00 Mn |
| Mar 31, 2026 | -30.00 Mn |
| Jun 30, 2025 | -10.00 Mn |
| Dec 31, 2023 | -1.84 Mn |
| Sep 30, 2023 | -14.91 Mn |
| Jun 30, 2023 | 130.49 Mn |
API Access
Spyre Therapeutics Other Operating Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=other-operating-expenses&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "other-operating-expenses", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=other-operating-expenses&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();