Spyre Therapeutics (SYRE) Liabilities and Shareholders Equity (2015 - 2026)
Spyre Therapeutics posted quarterly Liabilities and Shareholders Equity of $764.0 million for Q1 2026, up 34.08% year-on-year from $569.8 million in Q1 2025, and down 1.78% on a QoQ basis from $777.8 million in Q4 2025.
Spyre Therapeutics (SYRE) has 12 years of Liabilities and Shareholders Equity data on file, last reported at $764.0 million in Q1 2026.
- For the quarter ending Q1 2026, Liabilities and Shareholders Equity rose 34.08% year-over-year to $764.0 million; the trailing twelve-month figure through Mar 2026 stood at $2.6 billion (up 27.01% YoY), and the FY2025 full-year result was $777.8 million, up 27.82% from the prior year.
- Liabilities and Shareholders Equity for Q1 2026 stood at $764.0 million, down from $777.8 million in the prior quarter.
- Across five years, Liabilities and Shareholders Equity topped out at $777.8 million in Q4 2025 and bottomed at $52.5 million in Q1 2023.
- The 5-year median for Liabilities and Shareholders Equity is $421.1 million (2024), against an average of $370.9 million.
- The widest annual swing landed in 2022, when Liabilities and Shareholders Equity slumped 49.17%; it then surged 829.6% in 2024.
- A 5-year view of Liabilities and Shareholders Equity shows it stood at $71.1 million in 2022, then soared by 380.52% to $341.9 million in 2023, then soared by 77.99% to $608.5 million in 2024, then climbed by 27.82% to $777.8 million in 2025, then decreased by 1.78% to $764.0 million in 2026.
- The last three Liabilities and Shareholders Equity figures came in at $764.0 million (Q1 2026), $777.8 million (Q4 2025), and $504.6 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Liabilities and Shareholders Equity (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 14.93 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | 37.37 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 1.73 Bn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | 78.88 Mn |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 33.89 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 26.48 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | 23.64 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 40.87 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 5.13 Bn |
| 10 | Spyre Therapeutics | 5.55 Bn | 5.55 Bn | - | 763.95 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 763.95 Mn |
| Dec 31, 2025 | 777.78 Mn |
| Sep 30, 2025 | 504.60 Mn |
| Jun 30, 2025 | 538.83 Mn |
| Mar 31, 2025 | 569.78 Mn |
| Dec 31, 2024 | 608.48 Mn |
| Sep 30, 2024 | 421.09 Mn |
| Jun 30, 2024 | 436.07 Mn |
| Mar 31, 2024 | 487.60 Mn |
| Dec 31, 2023 | 341.86 Mn |
| Sep 30, 2023 | 207.27 Mn |
| Jun 30, 2023 | 243.53 Mn |
| Mar 31, 2023 | 52.45 Mn |
| Dec 31, 2022 | 71.14 Mn |
| Sep 30, 2022 | 91.57 Mn |
| Jun 30, 2022 | 106.71 Mn |
| Mar 31, 2022 | 83.17 Mn |
| Dec 31, 2021 | 109.93 Mn |
| Sep 30, 2021 | 129.06 Mn |
| Jun 30, 2021 | 146.98 Mn |
| Mar 31, 2021 | 163.61 Mn |
| Dec 31, 2020 | 161.62 Mn |
| Sep 30, 2020 | 155.63 Mn |
| Jun 30, 2020 | 172.91 Mn |
| Mar 31, 2020 | 64.78 Mn |
| Dec 31, 2019 | 83.18 Mn |
| Sep 30, 2019 | 100.10 Mn |
| Jun 30, 2019 | 117.49 Mn |
| Mar 31, 2019 | 128.52 Mn |
| Dec 31, 2018 | 77.74 Mn |
| Sep 30, 2018 | 71.28 Mn |
| Jun 30, 2018 | 79.71 Mn |
| Mar 31, 2018 | 49.79 Mn |
| Dec 31, 2017 | 56.08 Mn |
| Sep 30, 2017 | 60.50 Mn |
| Jun 30, 2017 | 67.14 Mn |
| Mar 31, 2017 | 61.27 Mn |
| Dec 31, 2016 | 67.06 Mn |
| Sep 30, 2016 | 72.06 Mn |
| Jun 30, 2016 | 77.30 Mn |
| Mar 31, 2016 | 35.54 Mn |
| Dec 31, 2015 | 38.65 Mn |