Spyre Therapeutics (SYRE) Shares Issued (2017 - 2026)
Spyre Therapeutics posted quarterly Shares Issued of $2.7 million for Q1 2026, up 1127.52% year-on-year from $218000.0 in Q1 2025, and down 19.06% on a QoQ basis from $3.3 million in Q4 2025.
Spyre Therapeutics (SYRE) has 10 years of Shares Issued data on file, last reported at $2.7 million in Q1 2026.
- For the quarter ending Q1 2026, Shares Issued rose 1127.52% year-over-year to $2.7 million; the trailing twelve-month figure through Mar 2026 stood at $5.8 million (up 103.57% YoY), and the FY2025 full-year result was $3.3 million, down 55.98% from the prior year.
- Shares Issued for Q1 2026 stood at $2.7 million, down from $3.3 million in the prior quarter.
- Across five years, Shares Issued topped out at $169.2 million in Q1 2024 and bottomed at -$164.3 million in Q2 2024.
- The 5-year median for Shares Issued is $201000.0 (2022), against an average of $1.0 million.
- Peak annual rise in Shares Issued reached 939927.78% in 2024, while the deepest fall reached 57312.41% in 2024.
- A 5-year view of Shares Issued shows it stood at $38000.0 in 2022, then soared by 642.11% to $282000.0 in 2023, then plunged by 57312.41% to -$161.3 million in 2024, then soared by 102.05% to $3.3 million in 2025, then decreased by 19.06% to $2.7 million in 2026.
- The last three Shares Issued figures came in at $2.7 million (Q1 2026), $3.3 million (Q4 2025), and -$1.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares Issued (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 5.40 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | - |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 27.00 Mn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 163.10 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 13.16 Mn |
| 10 | Spyre Therapeutics | 5.55 Bn | 5.55 Bn | - | 2.68 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 2.68 Mn |
| Mar 31, 2026 | 2.68 Mn |
| Dec 31, 2025 | 3.31 Mn |
| Dec 31, 2025 | 3.31 Mn |
| Sep 30, 2025 | -1.07 Mn |
| Sep 30, 2025 | -1.07 Mn |
| Jun 30, 2025 | 848,000.00 |
| Jun 30, 2025 | 848,000.00 |
| Mar 31, 2025 | 218,000.00 |
| Mar 31, 2025 | 218,000.00 |
| Dec 31, 2024 | -161.34 Mn |
| Dec 31, 2024 | -161.34 Mn |
| Sep 30, 2024 | 163.97 Mn |
| Sep 30, 2024 | 163.97 Mn |
| Jun 30, 2024 | -164.32 Mn |
| Jun 30, 2024 | -164.32 Mn |
| Mar 31, 2024 | 169.21 Mn |
| Mar 31, 2024 | 169.21 Mn |
| Dec 31, 2023 | 282,000.00 |
| Dec 31, 2023 | 282,000.00 |
| Sep 30, 2023 | 105,000.00 |
| Sep 30, 2023 | 105,000.00 |
| Mar 31, 2023 | 18,000.00 |
| Mar 31, 2023 | 18,000.00 |
| Sep 30, 2022 | 38,000.00 |
| Sep 30, 2022 | 38,000.00 |
| Mar 31, 2022 | 184,000.00 |
| Mar 31, 2022 | 184,000.00 |
| Dec 31, 2021 | -1.65 Mn |
| Dec 31, 2021 | -1.65 Mn |
| Sep 30, 2021 | 1.25 Mn |
| Sep 30, 2021 | 1.25 Mn |
| Jun 30, 2021 | 36,000.00 |
| Jun 30, 2021 | 36,000.00 |
| Mar 31, 2021 | 367,000.00 |
| Mar 31, 2021 | 367,000.00 |
| Dec 31, 2020 | 24.60 Mn |
| Dec 31, 2020 | 24.60 Mn |
| Sep 30, 2020 | 411,000.00 |
| Sep 30, 2020 | 411,000.00 |
| Jun 30, 2020 | -128.67 Mn |
| Jun 30, 2020 | -128.67 Mn |
| Mar 31, 2020 | 289,000.00 |
| Mar 31, 2020 | 289,000.00 |
| Dec 31, 2019 | 624,000.00 |
| Dec 31, 2019 | 624,000.00 |
| Sep 30, 2019 | 376,000.00 |
| Sep 30, 2019 | 376,000.00 |
| Jun 30, 2019 | 51,000.00 |
| Jun 30, 2019 | 51,000.00 |
| Mar 31, 2019 | 399,000.00 |
| Mar 31, 2019 | 399,000.00 |
| Dec 31, 2018 | 867,000.00 |
| Dec 31, 2018 | 867,000.00 |
| Sep 30, 2018 | 1.09 Mn |
| Sep 30, 2018 | 1.09 Mn |
| Jun 30, 2018 | 373,000.00 |
| Jun 30, 2018 | 373,000.00 |
| Mar 31, 2018 | 688,000.00 |
| Mar 31, 2018 | 688,000.00 |
| Dec 31, 2017 | 684,000.00 |
| Dec 31, 2017 | 684,000.00 |
| Sep 30, 2017 | 53,000.00 |
| Sep 30, 2017 | 53,000.00 |
| Mar 31, 2017 | 96,000.00 |
| Mar 31, 2017 | 96,000.00 |