Spyre Therapeutics (SYRE) Shares Issued (2017 - 2026)

Spyre Therapeutics (SYRE) reported Shares Issued of $2.7 million for Q1 2026, up 1127.52% on a YoY basis from $218000.0 in Q1 2025, and down 19.06% quarter-over-quarter from $3.3 million in Q4 2025.

Spyre Therapeutics (SYRE) Shares Issued (2017 - 2026) Analysis & Trends

Spyre Therapeutics has reported Shares Issued for 10 years, with the latest figure at $2.7 million in Q1 2026.

  • For the quarter ending Q1 2026, Shares Issued rose 1127.52% year-over-year to $2.7 million; the trailing twelve-month figure through Mar 2026 stood at $5.8 million (up 103.57% YoY), and the FY2025 full-year result was $3.3 million, down 55.98% from the prior year.
  • Shares Issued for Q1 2026 stood at $2.7 million, down from $3.3 million in the prior quarter.
  • The five-year high for Shares Issued was $169.2 million in Q1 2024, with the low at -$164.3 million in Q2 2024.
  • Historically, Shares Issued has averaged $1.0 million across 5 years, with a median of $201000.0 in 2022.
  • The largest YoY upside for Shares Issued was 939927.78% in 2024 against a maximum downside of 57312.41% in 2024.
  • Spyre Therapeutics' Shares Issued stood at $38000.0 in 2022, then surged by 642.11% to $282000.0 in 2023, then sank by 57312.41% to -$161.3 million in 2024, then surged by 102.05% to $3.3 million in 2025, then retreated by 19.06% to $2.7 million in 2026.
  • The last three Shares Issued figures came in at $2.7 million (Q1 2026), $3.3 million (Q4 2025), and -$1.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares Issued (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 5.40 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 27.00 Mn
9 Abivax 91.96 Bn 91.96 Bn - 26,927.15
10 Spyre Therapeutics 6.95 Bn 6.95 Bn - 2.68 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 2.68 Mn
Mar 31, 2026 2.68 Mn
Dec 31, 2025 3.31 Mn
Dec 31, 2025 3.31 Mn
Sep 30, 2025 -1.07 Mn
Sep 30, 2025 -1.07 Mn
Jun 30, 2025 848,000.00
Jun 30, 2025 848,000.00
Mar 31, 2025 218,000.00
Mar 31, 2025 218,000.00
Dec 31, 2024 -161.34 Mn
Dec 31, 2024 -161.34 Mn
Sep 30, 2024 163.97 Mn
Sep 30, 2024 163.97 Mn
Jun 30, 2024 -164.32 Mn
Jun 30, 2024 -164.32 Mn
Mar 31, 2024 169.21 Mn
Mar 31, 2024 169.21 Mn
Dec 31, 2023 282,000.00
Dec 31, 2023 282,000.00