Spyre Therapeutics (SYRE) Other Non Operating Income (2015 - 2026)

Spyre Therapeutics (SYRE) reported Other Non Operating Income of -$30.4 million for Q1 2026, down 1428.04% on a YoY basis from $2.3 million in Q1 2025, and down 142.93% quarter-over-quarter from -$12.5 million in Q4 2025.

Spyre Therapeutics (SYRE) Other Non Operating Income (2015 - 2026) Analysis & Trends

Spyre Therapeutics has reported Other Non Operating Income for 12 years, with the latest figure at -$30.4 million in Q1 2026.

  • For the quarter ending Q1 2026, Other Non Operating Income fell 1428.04% year-over-year to -$30.4 million; the trailing twelve-month figure through Mar 2026 stood at -$3.2 million (up 82.24% YoY), and the FY2025 full-year result was $29.5 million, up 242.22% from the prior year.
  • Other Non Operating Income for Q1 2026 stood at -$30.4 million, down from -$12.5 million in the prior quarter.
  • The five-year high for Other Non Operating Income was $40.3 million in Q3 2025, with the low at -$30.4 million in Q1 2026.
  • Historically, Other Non Operating Income has averaged -$2.4 million across 5 years, with a median of -$72000.0 in 2023.
  • The largest YoY upside for Other Non Operating Income was 9658.33% in 2023 against a maximum downside of 66750.0% in 2023.
  • Spyre Therapeutics' Other Non Operating Income stood at -$32000.0 in 2022, then plunged by 66750.0% to -$21.4 million in 2023, then surged by 96.18% to -$818000.0 in 2024, then tumbled by 1427.75% to -$12.5 million in 2025, then plunged by 142.93% to -$30.4 million in 2026.
  • The last three Other Non Operating Income figures came in at -$30.4 million (Q1 2026), -$12.5 million (Q4 2025), and $40.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn -
7 Psyence Biomedical 212.16 Bn 212.16 Bn -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn
9 Abivax 91.96 Bn 91.96 Bn -
10 Spyre Therapeutics 6.95 Bn 6.95 Bn -

Historic Data

Download Data
DateValue
Mar 31, 2026 -30.36 Mn
Dec 31, 2025 -12.50 Mn
Sep 30, 2025 40.33 Mn
Jun 30, 2025 -656,000.00
Mar 31, 2025 2.29 Mn
Dec 31, 2024 -818,000.00
Sep 30, 2024 -18.80 Mn
Jun 30, 2024 -610,000.00
Mar 31, 2024 -483,000.00
Dec 31, 2023 -21.39 Mn
Sep 30, 2023 2.34 Mn
Jun 30, 2023 -8,000.00
Mar 31, 2023 -72,000.00
Dec 31, 2022 -32,000.00
Sep 30, 2022 24,000.00
Jun 30, 2022 5,000.00
Mar 31, 2022 -30,000.00
Dec 31, 2021 -15,000.00
Sep 30, 2021 -24,000.00
Jun 30, 2021 -52,000.00