Spyre Therapeutics (SYRE) Other Non Operating Income (2015 - 2026)

Spyre Therapeutics posted quarterly Other Non Operating Income of -$30.4 million for Q1 2026, down 1428.04% year-on-year from $2.3 million in Q1 2025, and down 142.93% on a QoQ basis from -$12.5 million in Q4 2025.

Spyre Therapeutics (SYRE) has 12 years of Other Non Operating Income data on file, last reported at -$30.4 million in Q1 2026.

  • For the quarter ending Q1 2026, Other Non Operating Income fell 1428.04% year-over-year to -$30.4 million; the trailing twelve-month figure through Mar 2026 stood at -$3.2 million (up 82.24% YoY), and the FY2025 full-year result was $29.5 million, up 242.22% from the prior year.
  • Other Non Operating Income for Q1 2026 stood at -$30.4 million, down from -$12.5 million in the prior quarter.
  • Across five years, Other Non Operating Income topped out at $40.3 million in Q3 2025 and bottomed at -$30.4 million in Q1 2026.
  • The 5-year median for Other Non Operating Income is -$72000.0 (2023), against an average of -$2.4 million.
  • Peak annual rise in Other Non Operating Income reached 9658.33% in 2023, while the deepest fall reached 66750.0% in 2023.
  • A 5-year view of Other Non Operating Income shows it stood at -$32000.0 in 2022, then tumbled by 66750.0% to -$21.4 million in 2023, then soared by 96.18% to -$818000.0 in 2024, then slumped by 1427.75% to -$12.5 million in 2025, then tumbled by 142.93% to -$30.4 million in 2026.
  • The last three Other Non Operating Income figures came in at -$30.4 million (Q1 2026), -$12.5 million (Q4 2025), and $40.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn
10 Spyre Therapeutics 5.55 Bn 5.55 Bn -

Historic Data

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DateValue
Mar 31, 2026 -30.36 Mn
Dec 31, 2025 -12.50 Mn
Sep 30, 2025 40.33 Mn
Jun 30, 2025 -656,000.00
Mar 31, 2025 2.29 Mn
Dec 31, 2024 -818,000.00
Sep 30, 2024 -18.80 Mn
Jun 30, 2024 -610,000.00
Mar 31, 2024 -483,000.00
Dec 31, 2023 -21.39 Mn
Sep 30, 2023 2.34 Mn
Jun 30, 2023 -8,000.00
Mar 31, 2023 -72,000.00
Dec 31, 2022 -32,000.00
Sep 30, 2022 24,000.00
Jun 30, 2022 5,000.00
Mar 31, 2022 -30,000.00
Dec 31, 2021 -15,000.00
Sep 30, 2021 -24,000.00
Jun 30, 2021 -52,000.00
Mar 31, 2021 -31,000.00
Dec 31, 2020 18,000.00
Sep 30, 2020 2,000.00
Jun 30, 2020 -19,000.00
Mar 31, 2020 -6,000.00
Dec 31, 2019 -18,000.00
Sep 30, 2019 -12,000.00
Jun 30, 2019 -16,000.00
Mar 31, 2019 -17,000.00
Dec 31, 2018 -20,000.00
Sep 30, 2018 -13,000.00
Jun 30, 2018 -7,000.00
Mar 31, 2018 -17,000.00
Dec 31, 2017 -7,000.00
Sep 30, 2017 -12,000.00
Jun 30, 2017 -12,000.00
Mar 31, 2017 -11,000.00
Dec 31, 2016 -12,000.00
Sep 30, 2016 -9,000.00
Jun 30, 2016 -9,000.00
Mar 31, 2016 -6,000.00
Dec 31, 2015 -1,000.00
Sep 30, 2015 -1,000.00