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Spyre Therapeutics (SYRE) Change in Cash (2016 - 2025)

Historic Change in Cash for Spyre Therapeutics (SYRE) over the last 11 years, with Q3 2025 value amounting to -$16.8 million.

  • Spyre Therapeutics' Change in Cash fell 16418.53% to -$16.8 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$6.7 million, marking a year-over-year increase of 6710.96%. This contributed to the annual value of -$99.8 million for FY2024, which is 16530.93% down from last year.
  • Latest data reveals that Spyre Therapeutics reported Change in Cash of -$16.8 million as of Q3 2025, which was down 16418.53% from $33.2 million recorded in Q2 2025.
  • Over the past 5 years, Spyre Therapeutics' Change in Cash peaked at $200.1 million during Q2 2023, and registered a low of -$182.4 million during Q2 2024.
  • In the last 5 years, Spyre Therapeutics' Change in Cash had a median value of -$515000.0 in 2022 and averaged -$1.4 million.
  • In the last 5 years, Spyre Therapeutics' Change in Cash plummeted by 1173794.21% in 2023 and then skyrocketed by 2811605.84% in 2024.
  • Over the past 5 years, Spyre Therapeutics' Change in Cash (Quarter) stood at -$9.5 million in 2021, then skyrocketed by 56.92% to -$4.1 million in 2022, then soared by 2472.4% to $97.3 million in 2023, then tumbled by 81.66% to $17.8 million in 2024, then tumbled by 193.94% to -$16.8 million in 2025.
  • Its Change in Cash stands at -$16.8 million for Q3 2025, versus $33.2 million for Q2 2025 and -$40.9 million for Q1 2025.