Spyre Therapeutics (SYRE) Market Capitalization (2016 - 2026)
Spyre Therapeutics' Market Capitalization was $8.01 billion in Q3 2026, up 690.2% from $1.01 billion a year earlier and up 2.4% from the prior quarter.
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Analysis
Spyre Therapeutics (SYRE) Market Capitalization (2016 - 2026) Analysis & Trends
For FY2025, Market Capitalization at Spyre Therapeutics came in at $2.11 billion, up 90.9% from FY2024.
- Market Capitalization shows a five-year compound annual growth rate of -25.9% (FY2020 to FY2025).
- In earlier years, Market Capitalization was $1.11 billion in FY2024 (+599.8%), $157.96 million in FY2023 (-83.3%), $948.16 million in FY2022 (-87.9%) and $7.81 billion in FY2021 (-17.3%).
- The Q3 2026 figure marks the highest quarterly Market Capitalization since Q3 2021.
- Compared with a year earlier, Market Capitalization has increased for four straight quarters, with growth averaging 295.9% over the last eight quarters.
- The best year-over-year quarter for Market Capitalization over five years was Q2 2026 (growth of 765.1%); the worst was Q3 2023 (a decline of 95.0%).
- Per Business Quant data, SYRE's Market Capitalization in the three quarters before Q3 2026 was $7.82 billion (Q2 2026), $3.98 billion (Q1 2026) and $2.11 billion (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn |
| 10 | Spyre Therapeutics | 9.40 Bn | 5.68 Bn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 8.01 Bn |
| Jun 30, 2026 | 7.82 Bn |
| Mar 31, 2026 | 3.98 Bn |
| Dec 31, 2025 | 2.11 Bn |
| Sep 30, 2025 | 1.01 Bn |
| Jun 30, 2025 | 903.78 Mn |
| Mar 31, 2025 | 972.85 Mn |
| Dec 31, 2024 | 1.11 Bn |
| Sep 30, 2024 | 1.51 Bn |
| Jun 30, 2024 | 1.19 Bn |
| Mar 31, 2024 | 1.39 Bn |
| Dec 31, 2023 | 157.96 Mn |
| Sep 30, 2023 | 62.21 Mn |
| Jun 30, 2023 | 36.52 Mn |
| Mar 31, 2023 | 27.34 Mn |
| Dec 31, 2022 | 37.93 Mn |
| Sep 30, 2022 | 49.55 Mn |
| Jun 30, 2022 | 41.50 Mn |
| Mar 31, 2022 | 151.79 Mn |
| Dec 31, 2021 | 312.29 Mn |
API Access
Spyre Therapeutics Market Capitalization API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=market-capitalization&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "market-capitalization", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=market-capitalization&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();