Spyre Therapeutics (SYRE) Change in Intangibles (2025 - 2026)
Spyre Therapeutics (SYRE) posted Change in Intangibles of $40 million for Q2 2026, up 471.4% from $7 million a year earlier and up 33.3% from the prior quarter.
Spyre Therapeutics (SYRE) Change in Intangibles (2025 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Change in Intangibles at Spyre Therapeutics was $70 million, up 900.0% year-over-year; for FY2025, it came in at $7 million.
- In prior years, Spyre Therapeutics' Change in Intangibles was $15 million in FY2023.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change Intangibless (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 3.28 Bn |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | - |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | - |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | - |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | -437.00 Mn |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | -2.34 Bn |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | - |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | - |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | - |
| 10 | Spyre Therapeutics | 8.21 Bn | 8.21 Bn | - | 40.00 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 40.00 Mn |
| Mar 31, 2026 | 30.00 Mn |
| Jun 30, 2025 | 7.00 Mn |
Spyre Therapeutics Change in Intangibles API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=change-in-intangibles&ticker=SYRE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "change-in-intangibles", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=change-in-intangibles&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();