Spyre Therapeutics (SYRE) Accumulated Expenses (2015 - 2026)
Spyre Therapeutics (SYRE) reported Accumulated Expenses of $29.2 million for Q1 2026, up 34.81% on a YoY basis from $21.6 million in Q1 2025, and up 8.21% quarter-over-quarter from $26.9 million in Q4 2025.
Spyre Therapeutics (SYRE) Accumulated Expenses (2015 - 2026) Analysis & Trends
Spyre Therapeutics has reported Accumulated Expenses for 12 years, with the latest figure at $29.2 million in Q1 2026.
- For the quarter ending Q1 2026, Accumulated Expenses rose 34.81% year-over-year to $29.2 million; the trailing twelve-month figure through Mar 2026 stood at $29.2 million (up 34.81% YoY), and the FY2025 full-year result was $26.9 million, down 2.76% from the prior year.
- Accumulated Expenses for Q1 2026 stood at $29.2 million, up from $26.9 million in the prior quarter.
- The five-year high for Accumulated Expenses was $29.2 million in Q1 2026, with the low at $2.4 million in Q1 2022.
- Historically, Accumulated Expenses has averaged $17.5 million across 5 years, with a median of $15.9 million in 2023.
- Annual changes were most pronounced in 2022 — Accumulated Expenses jumped 353.12% — and 2024, when it tumbled 80.01%.
- Spyre Therapeutics' Accumulated Expenses stood at $12.8 million in 2022, then gained by 2.11% to $13.1 million in 2023, then surged by 111.41% to $27.7 million in 2024, then retreated by 2.76% to $26.9 million in 2025, then climbed by 8.21% to $29.2 million in 2026.
- The last three Accumulated Expenses figures came in at $29.2 million (Q1 2026), $26.9 million (Q4 2025), and $23.8 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - |
| 10 | Spyre Therapeutics | 6.95 Bn | 6.95 Bn | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 29.16 Mn |
| Dec 31, 2025 | 26.95 Mn |
| Sep 30, 2025 | 23.83 Mn |
| Jun 30, 2025 | 19.42 Mn |
| Mar 31, 2025 | 21.63 Mn |
| Dec 31, 2024 | 27.71 Mn |
| Sep 30, 2024 | 13.15 Mn |
| Jun 30, 2024 | 5.68 Mn |
| Mar 31, 2024 | 21.59 Mn |
| Dec 31, 2023 | 13.11 Mn |
| Sep 30, 2023 | 15.86 Mn |
| Jun 30, 2023 | 28.43 Mn |
| Mar 31, 2023 | 9.67 Mn |
| Dec 31, 2022 | 12.84 Mn |
| Sep 30, 2022 | 12.41 Mn |
| Jun 30, 2022 | 13.14 Mn |
| Mar 31, 2022 | 2.39 Mn |
| Dec 31, 2021 | 14.03 Mn |
| Sep 30, 2021 | 13.36 Mn |
| Jun 30, 2021 | 2.90 Mn |