Spyre Therapeutics (SYRE) Accumulated Expenses (2015 - 2026)
Spyre Therapeutics' (SYRE) quarterly Accumulated Expenses came in at $29.2 million in Q1 2026, up 34.81% YoY from $21.6 million in Q1 2025, and up 8.21% on a QoQ basis from $26.9 million in Q4 2025.
Analysis
Spyre Therapeutics (SYRE) Accumulated Expenses (2015 - 2026) Analysis & Trends
Spyre Therapeutics (SYRE) has 12 years of Accumulated Expenses data on file, last reported at $29.2 million in Q1 2026.
- Quarterly Accumulated Expenses rose 34.81% year-over-year to $29.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $29.2 million (up 34.81% YoY) and the FY2025 annual result came in at $26.9 million, down 2.76% from the prior year.
- Accumulated Expenses rose to $29.2 million in Q1 2026, from $26.9 million in the prior quarter.
- In the past five years, Accumulated Expenses ranged from a high of $29.2 million in Q1 2026 to a low of $2.4 million in Q1 2022.
- A 5-year average of $15.3 million and a median of $13.2 million in 2024 frame the typical range for Accumulated Expenses.
- Annual changes were most pronounced in 2022 — Accumulated Expenses sank 70.56% — and 2024, when it jumped 655.83%.
- Tracing SYRE's Accumulated Expenses over 5 years: stood at $12.8 million in 2022, then gained by 2.11% to $13.1 million in 2023, then surged by 111.41% to $27.7 million in 2024, then retreated by 2.76% to $26.9 million in 2025, then climbed by 8.21% to $29.2 million in 2026.
- The last three Accumulated Expenses figures came in at $29.2 million (Q1 2026), $26.9 million (Q4 2025), and $23.8 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn |
| 10 | Spyre Therapeutics | 7.53 Bn | 7.53 Bn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 26.18 Mn |
| Mar 31, 2026 | 29.16 Mn |
| Dec 31, 2025 | 26.95 Mn |
| Sep 30, 2025 | 23.83 Mn |
| Jun 30, 2025 | 19.42 Mn |
| Mar 31, 2025 | 21.63 Mn |
| Dec 31, 2024 | 27.71 Mn |
| Sep 30, 2024 | 13.15 Mn |
| Jun 30, 2024 | 5.68 Mn |
| Mar 31, 2024 | 21.59 Mn |
| Dec 31, 2023 | 13.11 Mn |
| Sep 30, 2023 | 15.86 Mn |
| Jun 30, 2023 | 28.43 Mn |
| Mar 31, 2023 | 9.67 Mn |
| Dec 31, 2022 | 12.84 Mn |
| Sep 30, 2022 | 12.41 Mn |
| Jun 30, 2022 | 13.14 Mn |
| Mar 31, 2022 | 10.79 Mn |
| Dec 31, 2021 | 14.03 Mn |
| Sep 30, 2021 | 13.36 Mn |