Spyre Therapeutics SYRE
NASDAQ SYRE
$89.10 +1.85 (+2.12%)
As of: Sep 4, 2026 · 3:59 PM EDT

Spyre Therapeutics (SYRE) Accumulated Expenses (2015 - 2026)

Spyre Therapeutics' (SYRE) quarterly Accumulated Expenses came in at $29.2 million in Q1 2026, up 34.81% YoY from $21.6 million in Q1 2025, and up 8.21% on a QoQ basis from $26.9 million in Q4 2025.

Analysis

Spyre Therapeutics (SYRE) Accumulated Expenses (2015 - 2026) Analysis & Trends

Spyre Therapeutics (SYRE) has 12 years of Accumulated Expenses data on file, last reported at $29.2 million in Q1 2026.

  • Quarterly Accumulated Expenses rose 34.81% year-over-year to $29.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $29.2 million (up 34.81% YoY) and the FY2025 annual result came in at $26.9 million, down 2.76% from the prior year.
  • Accumulated Expenses rose to $29.2 million in Q1 2026, from $26.9 million in the prior quarter.
  • In the past five years, Accumulated Expenses ranged from a high of $29.2 million in Q1 2026 to a low of $2.4 million in Q1 2022.
  • A 5-year average of $15.3 million and a median of $13.2 million in 2024 frame the typical range for Accumulated Expenses.
  • Annual changes were most pronounced in 2022 — Accumulated Expenses sank 70.56% — and 2024, when it jumped 655.83%.
  • Tracing SYRE's Accumulated Expenses over 5 years: stood at $12.8 million in 2022, then gained by 2.11% to $13.1 million in 2023, then surged by 111.41% to $27.7 million in 2024, then retreated by 2.76% to $26.9 million in 2025, then climbed by 8.21% to $29.2 million in 2026.
  • The last three Accumulated Expenses figures came in at $29.2 million (Q1 2026), $26.9 million (Q4 2025), and $23.8 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn -
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn
10 Spyre Therapeutics 7.53 Bn 7.53 Bn -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 26.18 Mn
Mar 31, 2026 29.16 Mn
Dec 31, 2025 26.95 Mn
Sep 30, 2025 23.83 Mn
Jun 30, 2025 19.42 Mn
Mar 31, 2025 21.63 Mn
Dec 31, 2024 27.71 Mn
Sep 30, 2024 13.15 Mn
Jun 30, 2024 5.68 Mn
Mar 31, 2024 21.59 Mn
Dec 31, 2023 13.11 Mn
Sep 30, 2023 15.86 Mn
Jun 30, 2023 28.43 Mn
Mar 31, 2023 9.67 Mn
Dec 31, 2022 12.84 Mn
Sep 30, 2022 12.41 Mn
Jun 30, 2022 13.14 Mn
Mar 31, 2022 10.79 Mn
Dec 31, 2021 14.03 Mn
Sep 30, 2021 13.36 Mn