Spyre Therapeutics (SYRE) Accumulated Expenses (2015 - 2026)
Spyre Therapeutics' Accumulated Expenses was $26.18 million in Q2 2026, up 34.9% from $19.42 million a year earlier but down 10.2% from the prior quarter.
Spyre Therapeutics (SYRE) Accumulated Expenses (2015 - 2026) Analysis & Trends
At the end of FY2025, Accumulated Expenses at Spyre Therapeutics came in at $26.95 million, down 2.8% from FY2024.
- Accumulated Expenses shows a five-year compound annual growth rate of 14.2% (FY2020 to FY2025).
- In earlier years, Accumulated Expenses was $27.71 million in FY2024 (+111.4%), $13.11 million in FY2023 (+2.1%), $12.84 million in FY2022 (-8.5%) and $14.03 million in FY2021 (+1.2%).
- Quarterly Accumulated Expenses has moved between $5.68 million (Q2 2024) and $29.16 million (Q1 2026) over five years.
- Compared with a year earlier, Accumulated Expenses was higher in six of the last eight quarters, with growth averaging 60.5%.
- The best year-over-year quarter for Accumulated Expenses over five years was Q2 2025 (growth of 241.7%); the worst was Q2 2024 (a decline of 80.0%).
- Per Business Quant data, SYRE's Accumulated Expenses in the three quarters before Q2 2026 was $29.16 million (Q1 2026), $26.95 million (Q4 2025) and $23.83 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn |
| 10 | Spyre Therapeutics | 8.21 Bn | 8.21 Bn | - |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 26.18 Mn |
| Mar 31, 2026 | 29.16 Mn |
| Dec 31, 2025 | 26.95 Mn |
| Sep 30, 2025 | 23.83 Mn |
| Jun 30, 2025 | 19.42 Mn |
| Mar 31, 2025 | 21.63 Mn |
| Dec 31, 2024 | 27.71 Mn |
| Sep 30, 2024 | 13.15 Mn |
| Jun 30, 2024 | 5.68 Mn |
| Mar 31, 2024 | 21.59 Mn |
| Dec 31, 2023 | 13.11 Mn |
| Sep 30, 2023 | 15.86 Mn |
| Jun 30, 2023 | 28.43 Mn |
| Mar 31, 2023 | 9.67 Mn |
| Dec 31, 2022 | 12.84 Mn |
| Sep 30, 2022 | 12.41 Mn |
| Jun 30, 2022 | 13.14 Mn |
| Mar 31, 2022 | 10.79 Mn |
| Dec 31, 2021 | 14.03 Mn |
| Sep 30, 2021 | 13.36 Mn |
Spyre Therapeutics Accumulated Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=accumulated-expenses&ticker=SYRE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "accumulated-expenses", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=accumulated-expenses&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();