Spyre Therapeutics (SYRE) Non Operating Income (2015 - 2026)
Spyre Therapeutics (SYRE) reported Non Operating Income of -$30.4 million for Q1 2026, down 445.81% on a YoY basis from $8.8 million in Q1 2025, and little changed quarter-over-quarter from -$30.2 million in Q4 2025.
Spyre Therapeutics (SYRE) Non Operating Income (2015 - 2026) Analysis & Trends
Spyre Therapeutics has reported Non Operating Income for 12 years, with the latest figure at -$30.4 million in Q1 2026.
- For the quarter ending Q1 2026, Non Operating Income fell 445.81% year-over-year to -$30.4 million; the trailing twelve-month figure through Mar 2026 stood at -$15.6 million (down 257.72% YoY), and the FY2025 full-year result was $29.5 million, up 4818.03% from the prior year.
- Non Operating Income for Q1 2026 stood at -$30.4 million, roughly flat from -$30.2 million in the prior quarter.
- The five-year high for Non Operating Income was $45.7 million in Q3 2025, with the low at -$98.8 million in Q4 2023.
- Historically, Non Operating Income has averaged -$5.7 million across 5 years, with a median of $109000.0 in 2022.
- The largest YoY upside for Non Operating Income was 6860.0% in 2023 against a maximum downside of 26230.95% in 2023.
- Spyre Therapeutics' Non Operating Income stood at $378000.0 in 2022, then tumbled by 26230.95% to -$98.8 million in 2023, then jumped by 120.75% to $20.5 million in 2024, then slumped by 247.57% to -$30.2 million in 2025, then decreased by 0.38% to -$30.4 million in 2026.
- The last three Non Operating Income figures came in at -$30.4 million (Q1 2026), -$30.2 million (Q4 2025), and $45.7 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Non Op. Inc. (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 5.75 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | - |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 444,000.00 |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | - |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | 9.35 Mn |
| 10 | Spyre Therapeutics | 6.95 Bn | 6.95 Bn | - | -30.36 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -30.36 Mn |
| Dec 31, 2025 | -30.24 Mn |
| Sep 30, 2025 | 45.71 Mn |
| Jun 30, 2025 | -656,000.00 |
| Mar 31, 2025 | 8.78 Mn |
| Dec 31, 2024 | 20.49 Mn |
| Sep 30, 2024 | -18.80 Mn |
| Jun 30, 2024 | -610,000.00 |
| Mar 31, 2024 | 3.95 Mn |
| Dec 31, 2023 | -98.78 Mn |
| Sep 30, 2023 | 2.34 Mn |
| Jun 30, 2023 | -8,000.00 |
| Mar 31, 2023 | 348,000.00 |
| Dec 31, 2022 | 378,000.00 |
| Sep 30, 2022 | 312,000.00 |
| Jun 30, 2022 | 109,000.00 |
| Mar 31, 2022 | 5,000.00 |
| Dec 31, 2021 | 96,000.00 |
| Sep 30, 2021 | 12,000.00 |
| Jun 30, 2021 | -52,000.00 |