Spyre Therapeutics (SYRE) Non Operating Income (2015 - 2026)
Spyre Therapeutics' (SYRE) quarterly Non Operating Income came in at -$23.4 million in Q1 2026, down 366.14% YoY from $8.8 million in Q1 2025, and down 336.06% on a QoQ basis from -$5.4 million in Q4 2025.
Analysis
Spyre Therapeutics (SYRE) Non Operating Income (2015 - 2026) Analysis & Trends
Spyre Therapeutics (SYRE) has 12 years of Non Operating Income data on file, last reported at -$23.4 million in Q1 2026.
- Quarterly Non Operating Income fell 366.14% year-over-year to -$23.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $22.2 million (up 308.93% YoY) and the FY2025 annual result came in at $54.3 million, up 8972.45% from the prior year.
- Non Operating Income slipped to -$23.4 million in Q1 2026, from -$5.4 million in the prior quarter.
- In the past five years, Non Operating Income ranged from a high of $45.7 million in Q3 2025 to a low of -$57.8 million in Q2 2023.
- A 5-year average of -$3.8 million and a median of $312000.0 in 2022 frame the typical range for Non Operating Income.
- The widest YoY moves for Non Operating Income: up 6860.0% in 2023, down 53153.21% in 2023.
- Tracing SYRE's Non Operating Income over 5 years: stood at $378000.0 in 2022, then slumped by 4667.72% to -$17.3 million in 2023, then jumped by 128.72% to $5.0 million in 2024, then tumbled by 208.07% to -$5.4 million in 2025, then plunged by 336.06% to -$23.4 million in 2026.
- The last three Non Operating Income figures came in at -$23.4 million (Q1 2026), -$5.4 million (Q4 2025), and $45.7 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Non Op. Inc. (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.62 Bn | 131.77 Bn | 2.84 Bn | - |
| 2 | Regeneron Pharmaceuticals | 85.73 Bn | 77.73 Bn | 3.93 Bn | 234.30 Mn |
| 3 | Argenx Se | 63.53 Bn | 58.35 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.23 Bn | 53.09 Bn | 52.00 Mn | - |
| 5 | Revolution Medicines | 44.05 Bn | 44.05 Bn | - | -139.24 Mn |
| 6 | BeOne Medicines | 40.03 Bn | 34.93 Bn | 1.53 Bn | - |
| 7 | Alnylam Pharmaceuticals | 35.50 Bn | 32.19 Bn | 992.69 Mn | -53.64 Mn |
| 8 | Royalty Pharma | 28.52 Bn | 27.68 Bn | - | -51.63 Mn |
| 9 | Insmed | 27.46 Bn | 26.30 Bn | 358.27 Mn | - |
| 10 | Spyre Therapeutics | 7.35 Bn | 7.35 Bn | - | 5.44 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 5.44 Mn |
| Mar 31, 2026 | -23.36 Mn |
| Dec 31, 2025 | -5.36 Mn |
| Sep 30, 2025 | 45.71 Mn |
| Jun 30, 2025 | 5.22 Mn |
| Mar 31, 2025 | 8.78 Mn |
| Dec 31, 2024 | 4.96 Mn |
| Sep 30, 2024 | -13.62 Mn |
| Jun 30, 2024 | 5.31 Mn |
| Mar 31, 2024 | 3.95 Mn |
| Dec 31, 2023 | -17.27 Mn |
| Sep 30, 2023 | -21.77 Mn |
| Jun 30, 2023 | -57.83 Mn |
| Mar 31, 2023 | 348,000.00 |
| Dec 31, 2022 | 378,000.00 |
| Sep 30, 2022 | 312,000.00 |
| Jun 30, 2022 | 109,000.00 |
| Mar 31, 2022 | 5,000.00 |
| Dec 31, 2021 | 19,000.00 |
| Sep 30, 2021 | 12,000.00 |