Spyre Therapeutics (SYRE) Non Operating Income (2015 - 2026)

Spyre Therapeutics (SYRE) reported Non Operating Income of -$30.4 million for Q1 2026, down 445.81% on a YoY basis from $8.8 million in Q1 2025, and little changed quarter-over-quarter from -$30.2 million in Q4 2025.

Spyre Therapeutics (SYRE) Non Operating Income (2015 - 2026) Analysis & Trends

Spyre Therapeutics has reported Non Operating Income for 12 years, with the latest figure at -$30.4 million in Q1 2026.

  • For the quarter ending Q1 2026, Non Operating Income fell 445.81% year-over-year to -$30.4 million; the trailing twelve-month figure through Mar 2026 stood at -$15.6 million (down 257.72% YoY), and the FY2025 full-year result was $29.5 million, up 4818.03% from the prior year.
  • Non Operating Income for Q1 2026 stood at -$30.4 million, roughly flat from -$30.2 million in the prior quarter.
  • The five-year high for Non Operating Income was $45.7 million in Q3 2025, with the low at -$98.8 million in Q4 2023.
  • Historically, Non Operating Income has averaged -$5.7 million across 5 years, with a median of $109000.0 in 2022.
  • The largest YoY upside for Non Operating Income was 6860.0% in 2023 against a maximum downside of 26230.95% in 2023.
  • Spyre Therapeutics' Non Operating Income stood at $378000.0 in 2022, then tumbled by 26230.95% to -$98.8 million in 2023, then jumped by 120.75% to $20.5 million in 2024, then slumped by 247.57% to -$30.2 million in 2025, then decreased by 0.38% to -$30.4 million in 2026.
  • The last three Non Operating Income figures came in at -$30.4 million (Q1 2026), -$30.2 million (Q4 2025), and $45.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Non Op. Inc. (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 5.75 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 444,000.00
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -
9 Abivax 91.96 Bn 91.96 Bn - 9.35 Mn
10 Spyre Therapeutics 6.95 Bn 6.95 Bn - -30.36 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -30.36 Mn
Dec 31, 2025 -30.24 Mn
Sep 30, 2025 45.71 Mn
Jun 30, 2025 -656,000.00
Mar 31, 2025 8.78 Mn
Dec 31, 2024 20.49 Mn
Sep 30, 2024 -18.80 Mn
Jun 30, 2024 -610,000.00
Mar 31, 2024 3.95 Mn
Dec 31, 2023 -98.78 Mn
Sep 30, 2023 2.34 Mn
Jun 30, 2023 -8,000.00
Mar 31, 2023 348,000.00
Dec 31, 2022 378,000.00
Sep 30, 2022 312,000.00
Jun 30, 2022 109,000.00
Mar 31, 2022 5,000.00
Dec 31, 2021 96,000.00
Sep 30, 2021 12,000.00
Jun 30, 2021 -52,000.00