Spyre Therapeutics (SYRE) Shares Outstanding (Diluted Average) (2020 - 2026)
Spyre Therapeutics posted quarterly Shares Outstanding (Diluted Average) of $346045.0 for Q1 2026, down 99.43% year-on-year from $60.3 million in Q1 2025, and down 99.46% on a QoQ basis from $64.1 million in Q4 2025.
Spyre Therapeutics (SYRE) has 7 years of Shares Outstanding (Diluted Average) data on file, last reported at $346045.0 in Q1 2026.
- For the quarter ending Q1 2026, Shares Outstanding (Diluted Average) fell 99.43% year-over-year to $346045.0; the trailing twelve-month figure through Mar 2026 stood at $346045.0 (down 99.43% YoY), and the FY2025 full-year result was $64.1 million, up 36.21% from the prior year.
- Shares Outstanding (Diluted Average) for Q1 2026 stood at $346045.0, down from $64.1 million in the prior quarter.
- Across five years, Shares Outstanding (Diluted Average) topped out at $82.2 million in Q2 2022 and bottomed at $346045.0 in Q2 2025.
- The 5-year median for Shares Outstanding (Diluted Average) is $5.6 million (2023), against an average of $26.8 million.
- The widest annual swing landed in 2025, when Shares Outstanding (Diluted Average) surged 13689.66%; it then sank 99.43% in 2026.
- A 5-year view of Shares Outstanding (Diluted Average) shows it stood at $3.2 million in 2022, then surged by 114.0% to $6.9 million in 2023, then surged by 581.85% to $47.0 million in 2024, then jumped by 36.21% to $64.1 million in 2025, then plunged by 99.46% to $346045.0 in 2026.
- The last three Shares Outstanding (Diluted Average) figures came in at $346045.0 (Q1 2026), $64.1 million (Q4 2025), and $346045.0 (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares (Diluted Avg.) (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 3.06 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 810.00 |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 118.76 Bn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 256.30 Mn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 107.70 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 138.23 Mn |
| 10 | Spyre Therapeutics | 5.55 Bn | 5.55 Bn | - | 346,045.00 |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 346,045.00 |
| Dec 31, 2025 | 64.06 Mn |
| Sep 30, 2025 | 346,045.00 |
| Jun 30, 2025 | 346,045.00 |
| Mar 31, 2025 | 60.27 Mn |
| Dec 31, 2024 | 47.03 Mn |
| Sep 30, 2024 | 44.26 Mn |
| Jun 30, 2024 | 40.91 Mn |
| Mar 31, 2024 | 437,037.00 |
| Dec 31, 2023 | 6.90 Mn |
| Sep 30, 2023 | 4.29 Mn |
| Jun 30, 2023 | 3.80 Mn |
| Mar 31, 2023 | 3.77 Mn |
| Sep 30, 2022 | 3.22 Mn |
| Jun 30, 2022 | 82.21 Mn |
| Mar 31, 2022 | 66.00 Mn |
| Dec 31, 2021 | 2.63 Mn |
| Sep 30, 2021 | 65.68 Mn |
| Jun 30, 2021 | 65.63 Mn |
| Dec 31, 2020 | 53.37 Mn |