Spyre Therapeutics (SYRE) Shares Outstanding (Diluted Average) (2020 - 2026)

Spyre Therapeutics (SYRE) reported Shares Outstanding (Diluted Average) of $346045.0 for Q1 2026, down 99.43% on a YoY basis from $60.3 million in Q1 2025, and down 99.46% quarter-over-quarter from $64.1 million in Q4 2025.

Spyre Therapeutics (SYRE) Shares Outstanding (Diluted Average) (2020 - 2026) Analysis & Trends

Spyre Therapeutics has reported Shares Outstanding (Diluted Average) for 7 years, with the latest figure at $346045.0 in Q1 2026.

  • For the quarter ending Q1 2026, Shares Outstanding (Diluted Average) fell 99.43% year-over-year to $346045.0; the trailing twelve-month figure through Mar 2026 stood at $346045.0 (down 99.43% YoY), and the FY2025 full-year result was $64.1 million, up 36.21% from the prior year.
  • Shares Outstanding (Diluted Average) for Q1 2026 stood at $346045.0, down from $64.1 million in the prior quarter.
  • The five-year high for Shares Outstanding (Diluted Average) was $82.2 million in Q2 2022, with the low at $346045.0 in Q2 2025.
  • Historically, Shares Outstanding (Diluted Average) has averaged $26.8 million across 5 years, with a median of $5.6 million in 2023.
  • Annual changes were most pronounced in 2025 — Shares Outstanding (Diluted Average) surged 13689.66% — and 2026, when it tumbled 99.43%.
  • Spyre Therapeutics' Shares Outstanding (Diluted Average) stood at $3.2 million in 2022, then jumped by 114.0% to $6.9 million in 2023, then jumped by 581.85% to $47.0 million in 2024, then soared by 36.21% to $64.1 million in 2025, then sank by 99.46% to $346045.0 in 2026.
  • The last three Shares Outstanding (Diluted Average) figures came in at $346045.0 (Q1 2026), $64.1 million (Q4 2025), and $346045.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares (Diluted Avg.) (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 4,489.46 Bn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 810.00
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 118.76 Bn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 1.48 Bn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 256.30 Mn
9 Abivax 91.96 Bn 91.96 Bn - 92.44 Mn
10 Spyre Therapeutics 6.95 Bn 6.95 Bn - 346,045.00

Historic Data

Download Data
DateValue
Mar 31, 2026 346,045.00
Dec 31, 2025 64.06 Mn
Sep 30, 2025 346,045.00
Jun 30, 2025 346,045.00
Mar 31, 2025 60.27 Mn
Dec 31, 2024 47.03 Mn
Sep 30, 2024 44.26 Mn
Jun 30, 2024 40.91 Mn
Mar 31, 2024 437,037.00
Dec 31, 2023 6.90 Mn
Sep 30, 2023 4.29 Mn
Jun 30, 2023 3.80 Mn
Mar 31, 2023 3.77 Mn
Sep 30, 2022 3.22 Mn
Jun 30, 2022 82.21 Mn
Mar 31, 2022 66.00 Mn
Dec 31, 2021 2.63 Mn
Sep 30, 2021 65.68 Mn
Jun 30, 2021 65.63 Mn
Dec 31, 2020 53.37 Mn