Spyre Therapeutics (SYRE) Change in Accured Expenses (2015 - 2026)
Spyre Therapeutics (SYRE) posted Change in Accured Expenses of $3.7 million for Q1 2026, up 16.93% on a QoQ basis from $3.1 million in Q4 2025, and up 160.9% year-over-year from $1.4 million in Q1 2025.
Spyre Therapeutics (SYRE) Change in Accured Expenses (2015 - 2026) Analysis & Trends
Spyre Therapeutics' Change in Accured Expenses history runs 12 years deep, the most recent figure standing at $3.7 million for Q1 2026.
- Quarterly Change in Accured Expenses rose 160.9% year-over-year to $3.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $8.9 million (up 1831.96% YoY) and the FY2025 annual result came in at -$764000.0, down 105.23% from the prior year.
- Change in Accured Expenses was $3.7 million for Q1 2026 at Spyre Therapeutics, up from $3.1 million in the prior quarter.
- Across five years, Change in Accured Expenses topped out at $14.9 million in Q4 2024 and bottomed at -$15.8 million in Q2 2024.
- A 5-year average of $692000.0 and a median of $450000.0 in 2022 frame the typical range for Change in Accured Expenses.
- Peak annual rise in Change in Accured Expenses reached 1768.46% in 2024, while the deepest fall reached 849.0% in 2024.
- Spyre Therapeutics' Change in Accured Expenses stood at $450000.0 in 2022, then sank by 298.0% to -$891000.0 in 2023, then jumped by 1768.46% to $14.9 million in 2024, then sank by 78.99% to $3.1 million in 2025, then advanced by 16.93% to $3.7 million in 2026.
- Business Quant data shows SYRE's Change in Accured Expenses at $3.7 million in Q1 2026, $3.1 million in Q4 2025, and $4.4 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Accured Expenses (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,222.41 Bn | 67,222.13 Bn | - | 1.13 Mn |
| 2 | Nanobiotix | 1,909.44 Bn | 1,909.38 Bn | - | - |
| 3 | Akari Therapeutics | 989.71 Bn | 989.71 Bn | - | 931,000.00 |
| 4 | BeOne Medicines | 471.12 Bn | 466.33 Bn | 1.35 Bn | -16.82 Mn |
| 5 | Vertex Pharmaceuticals | 121.84 Bn | 114.59 Bn | 2.59 Bn | 23.10 Mn |
| 6 | Regeneron Pharmaceuticals | 69.89 Bn | 61.14 Bn | 3.31 Bn | 107.70 Mn |
| 7 | Belite Bio | 62.74 Bn | 62.74 Bn | - | - |
| 8 | Argenx Se | 55.83 Bn | 50.64 Bn | 1.41 Bn | - |
| 9 | Alnylam Pharmaceuticals | 37.34 Bn | 34.34 Bn | 959.66 Mn | -176.03 Mn |
| 10 | Spyre Therapeutics | 259.00 Mn | 259.00 Mn | - | 3.65 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 3.65 Mn |
| Mar 31, 2026 | 3.65 Mn |
| Dec 31, 2025 | 3.12 Mn |
| Dec 31, 2025 | 3.12 Mn |
| Sep 30, 2025 | 4.41 Mn |
| Sep 30, 2025 | 4.41 Mn |
| Jun 30, 2025 | -2.30 Mn |
| Jun 30, 2025 | -2.30 Mn |
| Mar 31, 2025 | -6.00 Mn |
| Mar 31, 2025 | -6.00 Mn |
| Dec 31, 2024 | 14.87 Mn |
| Dec 31, 2024 | 14.87 Mn |
| Sep 30, 2024 | 7.37 Mn |
| Sep 30, 2024 | 7.37 Mn |
| Jun 30, 2024 | -15.77 Mn |
| Jun 30, 2024 | -15.77 Mn |
| Mar 31, 2024 | 8.15 Mn |
| Mar 31, 2024 | 8.15 Mn |
| Dec 31, 2023 | -891,000.00 |
| Dec 31, 2023 | -891,000.00 |