Spyre Therapeutics (SYRE) Change in Accured Expenses (2015 - 2026)
Spyre Therapeutics (SYRE) reported Change in Accured Expenses of $3.7 million for Q1 2026, up 160.9% on a YoY basis from $1.4 million in Q1 2025, and up 16.93% quarter-over-quarter from $3.1 million in Q4 2025.
Spyre Therapeutics (SYRE) Change in Accured Expenses (2015 - 2026) Analysis & Trends
Spyre Therapeutics has reported Change in Accured Expenses for 12 years, with the latest figure at $3.7 million in Q1 2026.
- For the quarter ending Q1 2026, Change in Accured Expenses rose 160.9% year-over-year to $3.7 million; the trailing twelve-month figure through Mar 2026 stood at $8.9 million (up 1831.96% YoY), and the FY2025 full-year result was -$764000.0, down 105.23% from the prior year.
- Change in Accured Expenses for Q1 2026 stood at $3.7 million, up from $3.1 million in the prior quarter.
- The five-year high for Change in Accured Expenses was $14.9 million in Q4 2024, with the low at -$15.8 million in Q2 2024.
- Historically, Change in Accured Expenses has averaged $692000.0 across 5 years, with a median of $450000.0 in 2022.
- The largest YoY upside for Change in Accured Expenses was 1768.46% in 2024 against a maximum downside of 849.0% in 2024.
- Spyre Therapeutics' Change in Accured Expenses stood at $450000.0 in 2022, then tumbled by 298.0% to -$891000.0 in 2023, then surged by 1768.46% to $14.9 million in 2024, then tumbled by 78.99% to $3.1 million in 2025, then rose by 16.93% to $3.7 million in 2026.
- The last three Change in Accured Expenses figures came in at $3.7 million (Q1 2026), $3.1 million (Q4 2025), and $4.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Accured Expenses (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | - |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 931,000.00 |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 644,700.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 70.50 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Spyre Therapeutics | 6.95 Bn | 6.95 Bn | - | 3.65 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 3.65 Mn |
| Mar 31, 2026 | 3.65 Mn |
| Dec 31, 2025 | 3.12 Mn |
| Dec 31, 2025 | 3.12 Mn |
| Sep 30, 2025 | 4.41 Mn |
| Sep 30, 2025 | 4.41 Mn |
| Jun 30, 2025 | -2.30 Mn |
| Jun 30, 2025 | -2.30 Mn |
| Mar 31, 2025 | -6.00 Mn |
| Mar 31, 2025 | -6.00 Mn |
| Dec 31, 2024 | 14.87 Mn |
| Dec 31, 2024 | 14.87 Mn |
| Sep 30, 2024 | 7.37 Mn |
| Sep 30, 2024 | 7.37 Mn |
| Jun 30, 2024 | -15.77 Mn |
| Jun 30, 2024 | -15.77 Mn |
| Mar 31, 2024 | 8.15 Mn |
| Mar 31, 2024 | 8.15 Mn |
| Dec 31, 2023 | -891,000.00 |
| Dec 31, 2023 | -891,000.00 |