Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026)
Spyre Therapeutics' (SYRE) quarterly Cash & Equivalents came in at $95.4 million in Q1 2026, up 96.83% YoY from $48.5 million in Q1 2025, and up 11.35% on a QoQ basis from $85.7 million in Q4 2025.
Analysis
Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026) Analysis & Trends
Spyre Therapeutics (SYRE) has 12 years of Cash & Equivalents data on file, last reported at $95.4 million in Q1 2026.
- Quarterly Cash & Equivalents rose 96.83% year-over-year to $95.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $95.4 million (up 96.83% YoY) and the FY2025 annual result came in at $85.7 million, down 2.29% from the prior year.
- Cash & Equivalents rose to $95.4 million in Q1 2026, from $85.7 million in the prior quarter.
- In the past five years, Cash & Equivalents ranged from a high of $235.4 million in Q2 2023 to a low of $14.6 million in Q1 2022.
- A 5-year average of $87.2 million and a median of $71.6 million in 2024 frame the typical range for Cash & Equivalents.
- Annual changes were most pronounced in 2022 — Cash & Equivalents plunged 81.76% — and 2024, when it surged 545.67%.
- Tracing SYRE's Cash & Equivalents over 5 years: stood at $34.9 million in 2022, then surged by 441.82% to $188.9 million in 2023, then plunged by 53.55% to $87.7 million in 2024, then fell by 2.29% to $85.7 million in 2025, then rose by 11.35% to $95.4 million in 2026.
- The last three Cash & Equivalents figures came in at $95.4 million (Q1 2026), $85.7 million (Q4 2025), and $64.9 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash & Equiv. (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 6.14 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 2.46 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 3.58 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | 1.72 Bn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | 815.44 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 5.10 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 1.71 Bn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 811.99 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 544.80 Mn |
| 10 | Spyre Therapeutics | 7.53 Bn | 7.53 Bn | - | 162.01 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 162.01 Mn |
| Mar 31, 2026 | 97.19 Mn |
| Dec 31, 2025 | 85.72 Mn |
| Sep 30, 2025 | 64.90 Mn |
| Jun 30, 2025 | 81.66 Mn |
| Mar 31, 2025 | 48.49 Mn |
| Dec 31, 2024 | 89.42 Mn |
| Sep 30, 2024 | 71.58 Mn |
| Jun 30, 2024 | 45.14 Mn |
| Mar 31, 2024 | 227.55 Mn |
| Dec 31, 2023 | 188.89 Mn |
| Sep 30, 2023 | 90.59 Mn |
| Jun 30, 2023 | 235.36 Mn |
| Mar 31, 2023 | 35.24 Mn |
| Dec 31, 2022 | 34.86 Mn |
| Sep 30, 2022 | 38.99 Mn |
| Jun 30, 2022 | 37.47 Mn |
| Mar 31, 2022 | 14.64 Mn |
| Dec 31, 2021 | 15.14 Mn |
| Sep 30, 2021 | 24.67 Mn |