Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026)
Spyre Therapeutics posted quarterly Cash & Equivalents of $97.2 million for Q1 2026, up 107.66% year-on-year from $46.8 million in Q1 2025, and up 13.37% on a QoQ basis from $85.7 million in Q4 2025.
Spyre Therapeutics (SYRE) has 12 years of Cash & Equivalents data on file, last reported at $97.2 million in Q1 2026.
- For the quarter ending Q1 2026, Cash & Equivalents rose 107.66% year-over-year to $97.2 million; the trailing twelve-month figure through Mar 2026 stood at $97.2 million (up 107.66% YoY), and the FY2025 full-year result was $85.7 million, down 2.29% from the prior year.
- Cash & Equivalents for Q1 2026 stood at $97.2 million, up from $85.7 million in the prior quarter.
- Across five years, Cash & Equivalents topped out at $235.4 million in Q2 2023 and bottomed at $14.6 million in Q1 2022.
- The 5-year median for Cash & Equivalents is $69.9 million (2024), against an average of $87.2 million.
- The widest annual swing landed in 2022, when Cash & Equivalents slumped 81.76%; it then surged 545.67% in 2024.
- A 5-year view of Cash & Equivalents shows it stood at $34.9 million in 2022, then soared by 441.82% to $188.9 million in 2023, then tumbled by 53.55% to $87.7 million in 2024, then retreated by 2.29% to $85.7 million in 2025, then gained by 13.37% to $97.2 million in 2026.
- The last three Cash & Equivalents figures came in at $97.2 million (Q1 2026), $85.7 million (Q4 2025), and $64.9 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash & Equiv. (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 1.91 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | 32.30 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 286.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | 61.46 Mn |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 2.77 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 5.49 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | 18.44 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 2.96 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 1.71 Bn |
| 10 | Spyre Therapeutics | 5.55 Bn | 5.55 Bn | - | 97.19 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 97.19 Mn |
| Dec 31, 2025 | 85.72 Mn |
| Sep 30, 2025 | 64.90 Mn |
| Jun 30, 2025 | 81.66 Mn |
| Mar 31, 2025 | 46.80 Mn |
| Dec 31, 2024 | 87.73 Mn |
| Sep 30, 2024 | 69.90 Mn |
| Jun 30, 2024 | 45.14 Mn |
| Mar 31, 2024 | 227.55 Mn |
| Dec 31, 2023 | 188.89 Mn |
| Sep 30, 2023 | 90.59 Mn |
| Jun 30, 2023 | 235.36 Mn |
| Mar 31, 2023 | 35.24 Mn |
| Dec 31, 2022 | 34.86 Mn |
| Sep 30, 2022 | 38.99 Mn |
| Jun 30, 2022 | 37.47 Mn |
| Mar 31, 2022 | 14.64 Mn |
| Dec 31, 2021 | 15.14 Mn |
| Sep 30, 2021 | 24.67 Mn |
| Jun 30, 2021 | 34.77 Mn |
| Mar 31, 2021 | 80.23 Mn |
| Dec 31, 2020 | 90.10 Mn |
| Sep 30, 2020 | 54.22 Mn |
| Jun 30, 2020 | 65.71 Mn |
| Mar 31, 2020 | 12.59 Mn |
| Dec 31, 2019 | 19.25 Mn |
| Sep 30, 2019 | 24.55 Mn |
| Jun 30, 2019 | 25.43 Mn |
| Mar 31, 2019 | 26.84 Mn |
| Dec 31, 2018 | 22.46 Mn |
| Sep 30, 2018 | 12.80 Mn |
| Jun 30, 2018 | 20.58 Mn |
| Mar 31, 2018 | 7.62 Mn |
| Dec 31, 2017 | 12.82 Mn |
| Sep 30, 2017 | 11.21 Mn |
| Jun 30, 2017 | 26.93 Mn |
| Mar 31, 2017 | 16.80 Mn |
| Dec 31, 2016 | 47.75 Mn |
| Sep 30, 2016 | 49.54 Mn |
| Jun 30, 2016 | 70.63 Mn |
| Mar 31, 2016 | 24.02 Mn |
| Dec 31, 2015 | 29.29 Mn |
| Sep 30, 2015 | 30.84 Mn |
| Jun 30, 2015 | 39.08 Mn |
| Mar 31, 2015 | 43.79 Mn |