Spyre Therapeutics SYRE
NASDAQ SYRE
$89.10 +1.85 (+2.12%)
As of: Sep 4, 2026 · 3:59 PM EDT

Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026)

Spyre Therapeutics' (SYRE) quarterly Cash & Equivalents came in at $95.4 million in Q1 2026, up 96.83% YoY from $48.5 million in Q1 2025, and up 11.35% on a QoQ basis from $85.7 million in Q4 2025.

Analysis

Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026) Analysis & Trends

Spyre Therapeutics (SYRE) has 12 years of Cash & Equivalents data on file, last reported at $95.4 million in Q1 2026.

  • Quarterly Cash & Equivalents rose 96.83% year-over-year to $95.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $95.4 million (up 96.83% YoY) and the FY2025 annual result came in at $85.7 million, down 2.29% from the prior year.
  • Cash & Equivalents rose to $95.4 million in Q1 2026, from $85.7 million in the prior quarter.
  • In the past five years, Cash & Equivalents ranged from a high of $235.4 million in Q2 2023 to a low of $14.6 million in Q1 2022.
  • A 5-year average of $87.2 million and a median of $71.6 million in 2024 frame the typical range for Cash & Equivalents.
  • Annual changes were most pronounced in 2022 — Cash & Equivalents plunged 81.76% — and 2024, when it surged 545.67%.
  • Tracing SYRE's Cash & Equivalents over 5 years: stood at $34.9 million in 2022, then surged by 441.82% to $188.9 million in 2023, then plunged by 53.55% to $87.7 million in 2024, then fell by 2.29% to $85.7 million in 2025, then rose by 11.35% to $95.4 million in 2026.
  • The last three Cash & Equivalents figures came in at $95.4 million (Q1 2026), $85.7 million (Q4 2025), and $64.9 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 6.14 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 2.46 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 3.58 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn 1.72 Bn
5 Revolution Medicines 44.33 Bn 44.33 Bn - 815.44 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 5.10 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 1.71 Bn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 811.99 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn 544.80 Mn
10 Spyre Therapeutics 7.53 Bn 7.53 Bn - 162.01 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 162.01 Mn
Mar 31, 2026 97.19 Mn
Dec 31, 2025 85.72 Mn
Sep 30, 2025 64.90 Mn
Jun 30, 2025 81.66 Mn
Mar 31, 2025 48.49 Mn
Dec 31, 2024 89.42 Mn
Sep 30, 2024 71.58 Mn
Jun 30, 2024 45.14 Mn
Mar 31, 2024 227.55 Mn
Dec 31, 2023 188.89 Mn
Sep 30, 2023 90.59 Mn
Jun 30, 2023 235.36 Mn
Mar 31, 2023 35.24 Mn
Dec 31, 2022 34.86 Mn
Sep 30, 2022 38.99 Mn
Jun 30, 2022 37.47 Mn
Mar 31, 2022 14.64 Mn
Dec 31, 2021 15.14 Mn
Sep 30, 2021 24.67 Mn