Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026)
Spyre Therapeutics (SYRE) posted Cash & Equivalents of $95.4 million for Q1 2026, up 11.35% on a QoQ basis from $85.7 million in Q4 2025, and up 96.83% year-over-year from $48.5 million in Q1 2025.
Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026) Analysis & Trends
Spyre Therapeutics' Cash & Equivalents history runs 12 years deep, the most recent figure standing at $95.4 million for Q1 2026.
- Quarterly Cash & Equivalents rose 96.83% year-over-year to $95.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $95.4 million (up 96.83% YoY) and the FY2025 annual result came in at $85.7 million, down 2.29% from the prior year.
- Cash & Equivalents was $95.4 million for Q1 2026 at Spyre Therapeutics, up from $85.7 million in the prior quarter.
- Across five years, Cash & Equivalents topped out at $235.4 million in Q2 2023 and bottomed at $14.6 million in Q1 2022.
- A 5-year average of $87.2 million and a median of $71.6 million in 2024 frame the typical range for Cash & Equivalents.
- Annual changes were most pronounced in 2022 — Cash & Equivalents tumbled 81.76% — and 2024, when it surged 545.67%.
- Spyre Therapeutics' Cash & Equivalents stood at $34.9 million in 2022, then jumped by 441.82% to $188.9 million in 2023, then slumped by 53.55% to $87.7 million in 2024, then decreased by 2.29% to $85.7 million in 2025, then advanced by 11.35% to $95.4 million in 2026.
- Business Quant data shows SYRE's Cash & Equivalents at $95.4 million in Q1 2026, $85.7 million in Q4 2025, and $64.9 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash & Equiv. (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,320.50 Bn | 66,320.21 Bn | - | 82.45 Mn |
| 2 | Nanobiotix | 1,933.82 Bn | 1,933.76 Bn | - | 61.40 Mn |
| 3 | Akari Therapeutics | 1,022.34 Bn | 1,022.34 Bn | - | 2.83 Mn |
| 4 | BeOne Medicines | 472.93 Bn | 468.14 Bn | 1.35 Bn | 4.79 Bn |
| 5 | Vertex Pharmaceuticals | 122.22 Bn | 114.98 Bn | 2.59 Bn | 5.49 Bn |
| 6 | Regeneron Pharmaceuticals | 69.96 Bn | 61.21 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 62.66 Bn | 62.66 Bn | - | - |
| 8 | Argenx Se | 56.07 Bn | 50.89 Bn | 1.41 Bn | 3.58 Bn |
| 9 | Alnylam Pharmaceuticals | 37.60 Bn | 34.59 Bn | 959.66 Mn | 1.71 Bn |
| 10 | Spyre Therapeutics | 259.67 Mn | 259.67 Mn | - | 95.45 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 95.45 Mn |
| Dec 31, 2025 | 85.72 Mn |
| Sep 30, 2025 | 64.90 Mn |
| Jun 30, 2025 | 79.96 Mn |
| Mar 31, 2025 | 48.49 Mn |
| Dec 31, 2024 | 87.73 Mn |
| Sep 30, 2024 | 71.58 Mn |
| Jun 30, 2024 | 45.14 Mn |
| Mar 31, 2024 | 227.55 Mn |
| Dec 31, 2023 | 188.89 Mn |
| Sep 30, 2023 | 90.59 Mn |
| Jun 30, 2023 | 235.36 Mn |
| Mar 31, 2023 | 35.24 Mn |
| Dec 31, 2022 | 34.86 Mn |
| Sep 30, 2022 | 38.99 Mn |
| Jun 30, 2022 | 37.47 Mn |
| Mar 31, 2022 | 14.64 Mn |
| Dec 31, 2021 | 15.14 Mn |
| Sep 30, 2021 | 24.67 Mn |
| Jun 30, 2021 | 34.77 Mn |