Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026)

Spyre Therapeutics (SYRE) reported Cash & Equivalents of $97.2 million for Q1 2026, up 107.66% on a YoY basis from $46.8 million in Q1 2025, and up 13.37% quarter-over-quarter from $85.7 million in Q4 2025.

Spyre Therapeutics (SYRE) Cash & Equivalents (2015 - 2026) Analysis & Trends

Spyre Therapeutics has reported Cash & Equivalents for 12 years, with the latest figure at $97.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Cash & Equivalents rose 107.66% year-over-year to $97.2 million; the trailing twelve-month figure through Mar 2026 stood at $97.2 million (up 107.66% YoY), and the FY2025 full-year result was $85.7 million, down 2.29% from the prior year.
  • Cash & Equivalents for Q1 2026 stood at $97.2 million, up from $85.7 million in the prior quarter.
  • The five-year high for Cash & Equivalents was $235.4 million in Q2 2023, with the low at $14.6 million in Q1 2022.
  • Historically, Cash & Equivalents has averaged $87.2 million across 5 years, with a median of $69.9 million in 2024.
  • Annual changes were most pronounced in 2022 — Cash & Equivalents plunged 81.76% — and 2024, when it surged 545.67%.
  • Spyre Therapeutics' Cash & Equivalents stood at $34.9 million in 2022, then surged by 441.82% to $188.9 million in 2023, then plunged by 53.55% to $87.7 million in 2024, then fell by 2.29% to $85.7 million in 2025, then rose by 13.37% to $97.2 million in 2026.
  • The last three Cash & Equivalents figures came in at $97.2 million (Q1 2026), $85.7 million (Q4 2025), and $64.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 1.91 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 7.15 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 5.49 Bn
9 Abivax 91.96 Bn 91.96 Bn - 558.94 Mn
10 Spyre Therapeutics 6.95 Bn 6.95 Bn - 97.19 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 97.19 Mn
Dec 31, 2025 85.72 Mn
Sep 30, 2025 64.90 Mn
Jun 30, 2025 81.66 Mn
Mar 31, 2025 46.80 Mn
Dec 31, 2024 87.73 Mn
Sep 30, 2024 69.90 Mn
Jun 30, 2024 45.14 Mn
Mar 31, 2024 227.55 Mn
Dec 31, 2023 188.89 Mn
Sep 30, 2023 90.59 Mn
Jun 30, 2023 235.36 Mn
Mar 31, 2023 35.24 Mn
Dec 31, 2022 34.86 Mn
Sep 30, 2022 38.99 Mn
Jun 30, 2022 37.47 Mn
Mar 31, 2022 14.64 Mn
Dec 31, 2021 15.14 Mn
Sep 30, 2021 24.67 Mn
Jun 30, 2021 34.77 Mn