Spyre Therapeutics (SYRE) Cash from Investing Activities (2015 - 2026)
Spyre Therapeutics (SYRE) recorded Cash from Investing Activities of -$297.9 million in Q2 2026, compared with $79 million a year earlier.
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Analysis
Spyre Therapeutics (SYRE) Cash from Investing Activities (2015 - 2026) Analysis & Trends
On a TTM basis, Spyre Therapeutics' Cash from Investing Activities came in at -$463.74 million as of Jun 30, 2026; for FY2025, it came in at -$143.48 million.
- Across earlier years, Cash from Investing Activities came in at -$353.29 million in FY2024, -$108.39 million in FY2023, $57.01 million in FY2022 and -$22.62 million in FY2021.
- The Q2 2026 figure is the lowest quarterly Cash from Investing Activities in data going back to Q1 2015.
- Peak year-over-year performance for Cash from Investing Activities in the last five years was growth of 801.3% in Q2 2023, against a decline of 66.2% in Q4 2021 at the low end.
- Per Business Quant, the preceding three quarters came in at $56.58 million (Q1 2026), -$247.41 million (Q4 2025) and $25 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Investing (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | -15.40 Bn |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | -1.11 Bn |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | -1.20 Bn |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | -5.60 Bn |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | -3.11 Bn |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | -2.91 Bn |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | -569.00 Mn |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -10.35 Bn |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 2.11 Bn |
| 10 | Spyre Therapeutics | 8.21 Bn | 8.21 Bn | - | -297.90 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -297.90 Mn |
| Mar 31, 2026 | 56.58 Mn |
| Dec 31, 2025 | -247.41 Mn |
| Sep 30, 2025 | 25.00 Mn |
| Jun 30, 2025 | 79.00 Mn |
| Mar 31, 2025 | -61,000.00 |
| Dec 31, 2024 | -170.54 Mn |
| Sep 30, 2024 | 42.74 Mn |
| Jun 30, 2024 | -120.52 Mn |
| Mar 31, 2024 | -104.96 Mn |
| Dec 31, 2023 | -35.27 Mn |
| Sep 30, 2023 | -97.63 Mn |
| Jun 30, 2023 | 6.76 Mn |
| Mar 31, 2023 | 17.75 Mn |
| Dec 31, 2022 | 14.00 Mn |
| Sep 30, 2022 | 16.50 Mn |
| Jun 30, 2022 | 750,000.00 |
| Mar 31, 2022 | 25.76 Mn |
| Dec 31, 2021 | 9.66 Mn |
| Sep 30, 2021 | 5.78 Mn |
API Access
Spyre Therapeutics Cash from Investing Activities API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=cash-from-investing-activities&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "cash-from-investing-activities", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=cash-from-investing-activities&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();