Spyre Therapeutics (SYRE) Payables (2015 - 2026)

Spyre Therapeutics' (SYRE) quarterly Payables came in at $56.0 million in Q1 2026, up 20.33% YoY from $46.5 million in Q1 2025, and up 76.37% on a QoQ basis from $31.7 million in Q4 2025.

Spyre Therapeutics (SYRE) Payables (2015 - 2026) Analysis & Trends

Spyre Therapeutics (SYRE) has 12 years of Payables data on file, last reported at $56.0 million in Q1 2026.

  • Quarterly Payables rose 20.33% year-over-year to $56.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $56.0 million (up 20.33% YoY) and the FY2025 annual result came in at $31.7 million, up 23.22% from the prior year.
  • Payables advanced to $56.0 million in Q1 2026, from $31.7 million in the prior quarter.
  • In the past five years, Payables ranged from a high of $63.6 million in Q2 2025 to a low of $2.0 million in Q2 2022.
  • A 5-year average of $20.6 million and a median of $13.8 million in 2023 frame the typical range for Payables.
  • Annual changes were most pronounced in 2023 — Payables jumped 1108.58% — and 2024, when it plunged 75.19%.
  • Tracing SYRE's Payables over 5 years: stood at $4.2 million in 2022, then slumped by 45.28% to $2.3 million in 2023, then surged by 1026.25% to $25.7 million in 2024, then gained by 23.22% to $31.7 million in 2025, then surged by 76.37% to $56.0 million in 2026.
  • The last three Payables figures came in at $56.0 million (Q1 2026), $31.7 million (Q4 2025), and $18.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Payables (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 429.50 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.16 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 1.52 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 88.42 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 470.30 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 3.05 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 35.57 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 108.02 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 428.93 Mn
10 Spyre Therapeutics 9.13 Bn 9.13 Bn - 37.07 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 37.07 Mn
Mar 31, 2026 55.95 Mn
Dec 31, 2025 31.72 Mn
Sep 30, 2025 18.48 Mn
Jun 30, 2025 63.61 Mn
Mar 31, 2025 46.50 Mn
Dec 31, 2024 25.75 Mn
Sep 30, 2024 29.91 Mn
Jun 30, 2024 5.87 Mn
Mar 31, 2024 5.70 Mn
Dec 31, 2023 2.29 Mn
Sep 30, 2023 9.19 Mn
Jun 30, 2023 23.66 Mn
Mar 31, 2023 2.06 Mn
Sep 30, 2022 4.18 Mn
Jun 30, 2022 1.96 Mn
Mar 31, 2022 2.98 Mn
Dec 31, 2021 3.32 Mn
Sep 30, 2021 1.86 Mn
Jun 30, 2021 2.22 Mn