Spyre Therapeutics (SYRE) Common Equity (2015 - 2026)
Spyre Therapeutics (SYRE) posted Common Equity of $670.8 million for Q1 2026, down 6.21% on a QoQ basis from $715.2 million in Q4 2025, and up 39.0% year-over-year from $482.6 million in Q1 2025.
Spyre Therapeutics (SYRE) Common Equity (2015 - 2026) Analysis & Trends
Spyre Therapeutics' Common Equity history runs 12 years deep, the most recent figure standing at $670.8 million for Q1 2026.
- Quarterly Common Equity rose 39.0% year-over-year to $670.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $670.8 million (up 39.0% YoY) and the FY2025 annual result came in at $715.2 million, up 38.13% from the prior year.
- Common Equity was $670.8 million for Q1 2026 at Spyre Therapeutics, down from $715.2 million in the prior quarter.
- Across five years, Common Equity topped out at $715.2 million in Q4 2025 and bottomed at -$245.4 million in Q3 2023.
- A 5-year average of $245.9 million and a median of $184.0 million in 2023 frame the typical range for Common Equity.
- Annual changes were most pronounced in 2023 — Common Equity tumbled 463.26% — and 2024, when it surged 352.48%.
- Spyre Therapeutics' Common Equity stood at $50.3 million in 2022, then surged by 265.8% to $184.0 million in 2023, then surged by 181.39% to $517.8 million in 2024, then soared by 38.13% to $715.2 million in 2025, then decreased by 6.21% to $670.8 million in 2026.
- Business Quant data shows SYRE's Common Equity at $670.8 million in Q1 2026, $715.2 million in Q4 2025, and $455.1 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Common Equity (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | 251.12 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | -98.34 Mn |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 4.76 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | 32.36 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 19.36 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 31.42 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | 795.79 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 1.50 Bn |
| 10 | Spyre Therapeutics | 257.83 Mn | 257.83 Mn | - | 670.81 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 670.81 Mn |
| Dec 31, 2025 | 715.24 Mn |
| Sep 30, 2025 | 455.10 Mn |
| Jun 30, 2025 | 455.77 Mn |
| Mar 31, 2025 | 482.61 Mn |
| Dec 31, 2024 | 517.80 Mn |
| Sep 30, 2024 | 327.39 Mn |
| Jun 30, 2024 | 374.39 Mn |
| Mar 31, 2024 | 152.27 Mn |
| Dec 31, 2023 | 184.02 Mn |
| Sep 30, 2023 | -245.40 Mn |
| Jun 30, 2023 | -207.37 Mn |
| Mar 31, 2023 | 33.65 Mn |
| Dec 31, 2022 | 50.31 Mn |
| Sep 30, 2022 | 67.56 Mn |
| Jun 30, 2022 | 84.16 Mn |
| Mar 31, 2022 | 61.66 Mn |
| Dec 31, 2021 | 83.94 Mn |
| Sep 30, 2021 | 102.08 Mn |
| Jun 30, 2021 | 119.02 Mn |