Spyre Therapeutics (SYRE) Common Equity (2015 - 2026)
Spyre Therapeutics posted quarterly Common Equity of $670.8 million for Q1 2026, up 39.0% year-on-year from $482.6 million in Q1 2025, and down 6.21% on a QoQ basis from $715.2 million in Q4 2025.
Spyre Therapeutics (SYRE) has 12 years of Common Equity data on file, last reported at $670.8 million in Q1 2026.
- For the quarter ending Q1 2026, Common Equity rose 39.0% year-over-year to $670.8 million; the trailing twelve-month figure through Mar 2026 stood at $670.8 million (up 39.0% YoY), and the FY2025 full-year result was $715.2 million, up 38.13% from the prior year.
- Common Equity for Q1 2026 stood at $670.8 million, down from $715.2 million in the prior quarter.
- Across five years, Common Equity topped out at $715.2 million in Q4 2025 and bottomed at -$245.4 million in Q3 2023.
- The 5-year median for Common Equity is $184.0 million (2023), against an average of $245.9 million.
- The widest annual swing landed in 2023, when Common Equity slumped 463.26%; it then surged 352.48% in 2024.
- A 5-year view of Common Equity shows it stood at $50.3 million in 2022, then jumped by 265.8% to $184.0 million in 2023, then jumped by 181.39% to $517.8 million in 2024, then surged by 38.13% to $715.2 million in 2025, then retreated by 6.21% to $670.8 million in 2026.
- The last three Common Equity figures came in at $670.8 million (Q1 2026), $715.2 million (Q4 2025), and $455.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Common Equity (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -1.42 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | 35.63 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 1.00 Bn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 14.38 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 19.36 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | 13.21 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 31.42 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 1.08 Bn |
| 10 | Spyre Therapeutics | 5.55 Bn | 5.55 Bn | - | 670.81 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 670.81 Mn |
| Dec 31, 2025 | 715.24 Mn |
| Sep 30, 2025 | 455.10 Mn |
| Jun 30, 2025 | 455.77 Mn |
| Mar 31, 2025 | 482.61 Mn |
| Dec 31, 2024 | 517.80 Mn |
| Sep 30, 2024 | 327.39 Mn |
| Jun 30, 2024 | 374.39 Mn |
| Mar 31, 2024 | 152.27 Mn |
| Dec 31, 2023 | 184.02 Mn |
| Sep 30, 2023 | -245.40 Mn |
| Jun 30, 2023 | -207.37 Mn |
| Mar 31, 2023 | 33.65 Mn |
| Dec 31, 2022 | 50.31 Mn |
| Sep 30, 2022 | 67.56 Mn |
| Jun 30, 2022 | 84.16 Mn |
| Mar 31, 2022 | 61.66 Mn |
| Dec 31, 2021 | 83.94 Mn |
| Sep 30, 2021 | 102.08 Mn |
| Jun 30, 2021 | 119.02 Mn |
| Mar 31, 2021 | 123.76 Mn |
| Dec 31, 2020 | 139.83 Mn |
| Sep 30, 2020 | 136.27 Mn |
| Jun 30, 2020 | 152.26 Mn |
| Mar 31, 2020 | 42.81 Mn |
| Dec 31, 2019 | 60.08 Mn |
| Sep 30, 2019 | 79.80 Mn |
| Jun 30, 2019 | 99.62 Mn |
| Mar 31, 2019 | 116.29 Mn |
| Dec 31, 2018 | 67.43 Mn |
| Sep 30, 2018 | 63.68 Mn |
| Jun 30, 2018 | 73.45 Mn |
| Mar 31, 2018 | 43.92 Mn |
| Dec 31, 2017 | 50.34 Mn |
| Sep 30, 2017 | 55.51 Mn |
| Jun 30, 2017 | 62.60 Mn |
| Mar 31, 2017 | 57.18 Mn |
| Dec 31, 2016 | 62.97 Mn |
| Sep 30, 2016 | 68.20 Mn |
| Jun 30, 2016 | 73.92 Mn |
| Mar 31, 2016 | -26.61 Mn |
| Dec 31, 2015 | -22.21 Mn |