Spyre Therapeutics (SYRE) Common Equity (2015 - 2026)
Spyre Therapeutics (SYRE) reported Common Equity of $670.8 million for Q1 2026, up 39.0% on a YoY basis from $482.6 million in Q1 2025, and down 6.21% quarter-over-quarter from $715.2 million in Q4 2025.
Spyre Therapeutics (SYRE) Common Equity (2015 - 2026) Analysis & Trends
Spyre Therapeutics has reported Common Equity for 12 years, with the latest figure at $670.8 million in Q1 2026.
- For the quarter ending Q1 2026, Common Equity rose 39.0% year-over-year to $670.8 million; the trailing twelve-month figure through Mar 2026 stood at $670.8 million (up 39.0% YoY), and the FY2025 full-year result was $715.2 million, up 38.13% from the prior year.
- Common Equity for Q1 2026 stood at $670.8 million, down from $715.2 million in the prior quarter.
- The five-year high for Common Equity was $715.2 million in Q4 2025, with the low at -$245.4 million in Q3 2023.
- Historically, Common Equity has averaged $245.9 million across 5 years, with a median of $184.0 million in 2023.
- Annual changes were most pronounced in 2023 — Common Equity plunged 463.26% — and 2024, when it surged 352.48%.
- Spyre Therapeutics' Common Equity stood at $50.3 million in 2022, then soared by 265.8% to $184.0 million in 2023, then soared by 181.39% to $517.8 million in 2024, then jumped by 38.13% to $715.2 million in 2025, then fell by 6.21% to $670.8 million in 2026.
- The last three Common Equity figures came in at $670.8 million (Q1 2026), $715.2 million (Q4 2025), and $455.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Common Equity (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 35.63 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -1.42 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | - |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | 13.21 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 14.38 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 11.87 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 19.36 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Spyre Therapeutics | 6.95 Bn | 6.95 Bn | - | 670.81 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 670.81 Mn |
| Dec 31, 2025 | 715.24 Mn |
| Sep 30, 2025 | 455.10 Mn |
| Jun 30, 2025 | 455.77 Mn |
| Mar 31, 2025 | 482.61 Mn |
| Dec 31, 2024 | 517.80 Mn |
| Sep 30, 2024 | 327.39 Mn |
| Jun 30, 2024 | 374.39 Mn |
| Mar 31, 2024 | 152.27 Mn |
| Dec 31, 2023 | 184.02 Mn |
| Sep 30, 2023 | -245.40 Mn |
| Jun 30, 2023 | -207.37 Mn |
| Mar 31, 2023 | 33.65 Mn |
| Dec 31, 2022 | 50.31 Mn |
| Sep 30, 2022 | 67.56 Mn |
| Jun 30, 2022 | 84.16 Mn |
| Mar 31, 2022 | 61.66 Mn |
| Dec 31, 2021 | 83.94 Mn |
| Sep 30, 2021 | 102.08 Mn |
| Jun 30, 2021 | 119.02 Mn |