Spyre Therapeutics SYRE
NASDAQ SYRE
$88.06 +0.81 (+0.92%)
As of: Sep 4, 2026 · 2:42 PM EDT

Spyre Therapeutics (SYRE) Income towards Parent Company (2015 - 2026)

Spyre Therapeutics' (SYRE) quarterly Income towards Parent Company came in at -$69.0 million in Q1 2026, down 54.12% YoY from -$150.4 million in Q1 2025, and down 10.36% on a QoQ basis from -$62.5 million in Q4 2025.

Analysis

Spyre Therapeutics (SYRE) Income towards Parent Company (2015 - 2026) Analysis & Trends

Spyre Therapeutics (SYRE) has 12 years of Income towards Parent Company data on file, last reported at -$69.0 million in Q1 2026.

  • Quarterly Income towards Parent Company fell 54.12% year-over-year to -$69.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$179.4 million (up 14.12% YoY) and the FY2025 annual result came in at -$155.2 million, up 25.39% from the prior year.
  • Income towards Parent Company eased to -$69.0 million in Q1 2026, from -$62.5 million in the prior quarter.
  • In the past five years, Income towards Parent Company ranged from a high of -$11.2 million in Q3 2025 to a low of -$217.1 million in Q2 2023.
  • A 5-year average of -$50.3 million and a median of -$40.1 million in 2023 frame the typical range for Income towards Parent Company.
  • Annual changes were most pronounced in 2023 — Income towards Parent Company sank 872.45% — and 2025, when it surged 83.8%.
  • Tracing SYRE's Income towards Parent Company over 5 years: stood at -$18.8 million in 2022, then slumped by 235.67% to -$63.2 million in 2023, then advanced by 10.9% to -$56.3 million in 2024, then decreased by 11.07% to -$62.5 million in 2025, then dropped by 10.36% to -$69.0 million in 2026.
  • The last three Income towards Parent Company figures came in at -$69.0 million (Q1 2026), -$62.5 million (Q4 2025), and -$11.2 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 138.74 Bn 130.89 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.52 Bn 77.52 Bn 3.93 Bn
3 Argenx Se 63.51 Bn 58.32 Bn 1.37 Bn
4 Moderna 58.04 Bn 52.91 Bn 52.00 Mn
5 Revolution Medicines 44.06 Bn 44.06 Bn -
6 BeOne Medicines 39.98 Bn 34.88 Bn 1.53 Bn
7 Alnylam Pharmaceuticals 35.46 Bn 32.15 Bn 992.69 Mn
8 Royalty Pharma 28.41 Bn 27.57 Bn -
9 Insmed 27.44 Bn 26.28 Bn 358.27 Mn
10 Spyre Therapeutics 7.46 Bn 7.46 Bn -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -36.20 Mn
Mar 31, 2026 -69.01 Mn
Dec 31, 2025 -62.53 Mn
Sep 30, 2025 -11.18 Mn
Jun 30, 2025 -36.72 Mn
Mar 31, 2025 -44.77 Mn
Dec 31, 2024 -56.30 Mn
Sep 30, 2024 -69.03 Mn
Jun 30, 2024 -38.84 Mn
Mar 31, 2024 -43.86 Mn
Dec 31, 2023 -63.18 Mn
Sep 30, 2023 -40.11 Mn
Jun 30, 2023 -217.08 Mn
Mar 31, 2023 -18.42 Mn
Dec 31, 2022 -18.82 Mn
Sep 30, 2022 -18.23 Mn
Jun 30, 2022 -22.32 Mn
Mar 31, 2022 -24.44 Mn
Dec 31, 2021 -20.45 Mn
Sep 30, 2021 -20.31 Mn