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Spyre Therapeutics (SYRE) Change in Acquisitions & Divestments (2016 - 2026)

Spyre Therapeutics' Change in Acquisitions & Divestments history spans 10 years, with the latest figure at $94.3 million for Q4 2025.

  • For Q4 2025, Change in Acquisitions & Divestments rose 50.76% year-over-year to $94.3 million; the TTM value through Dec 2025 reached $371.7 million, up 51.13%, while the annual FY2025 figure was $371.7 million, 51.13% up from the prior year.
  • Change in Acquisitions & Divestments reached $94.3 million in Q4 2025 per SYRE's latest filing, down from $99.2 million in the prior quarter.
  • In the past five years, Change in Acquisitions & Divestments ranged from a high of $106.9 million in Q2 2025 to a low of $3.2 million in Q2 2023.
  • Average Change in Acquisitions & Divestments over 5 years is $45.5 million, with a median of $32.1 million recorded in 2021.
  • Peak YoY movement for Change in Acquisitions & Divestments: crashed 87.0% in 2023, then skyrocketed 1680.8% in 2024.
  • A 5-year view of Change in Acquisitions & Divestments shows it stood at $22.9 million in 2021, then fell by 19.26% to $18.5 million in 2022, then increased by 2.16% to $18.9 million in 2023, then soared by 230.94% to $62.5 million in 2024, then soared by 50.76% to $94.3 million in 2025.
  • Per Business Quant, the three most recent readings for SYRE's Change in Acquisitions & Divestments are $94.3 million (Q4 2025), $99.2 million (Q3 2025), and $106.9 million (Q2 2025).