Spyre Therapeutics SYRE
NASDAQ SYRE
$105.63 +1.14 (+1.10%)
As of: Nov 11, 2026 · 12:40 PM EST

Spyre Therapeutics (SYRE) Shares Outstanding (2014 - 2026)

Updated

Spyre Therapeutics (SYRE) recorded Weighted Average Shares Outstanding of 88.41 million in Q3 2026, up 45.5% from 60.78 million a year earlier and up 4.3% from the prior quarter.

Analysis

Spyre Therapeutics (SYRE) Shares Outstanding (2014 - 2026) Analysis & Trends

For FY2025, Spyre Therapeutics reported Weighted Average Shares Outstanding of 64.42 million, up 35.7% from FY2024.

  • Annual Weighted Average Shares Outstanding has a five-year compound annual growth rate of 3.8% (FY2020 to FY2025).
  • Across earlier years, Weighted Average Shares Outstanding came in at 47.49 million in FY2024 (+546.9%), 7.34 million in FY2023 (-91.3%), 84.28 million in FY2022 (+28.2%) and 65.74 million in FY2021 (+23.2%).
  • The Q3 2026 figure is the highest quarterly Weighted Average Shares Outstanding since Q2 2023.
  • On a year-over-year basis, Weighted Average Shares Outstanding has increased for eight consecutive quarters, with growth averaging 101.4% over the last eight quarters.
  • Peak year-over-year performance for Weighted Average Shares Outstanding in the last five years was growth of 546.9% in Q4 2024, against a decline of 95.4% in Q3 2023 at the low end.
  • Per Business Quant, the preceding three quarters came in at 84.73 million (Q2 2026), 78.55 million (Q1 2026) and 64.42 million (Q4 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares Outstanding (Qtr)
1 Eli Lilly 1,348.13 Bn 1,321.74 Bn 20.46 Bn 891.90 Mn
2 Johnson & Johnson 675.90 Bn 595.76 Bn 17.30 Bn 2.41 Bn
3 AbbVie 519.45 Bn 487.50 Bn 13.12 Bn 1.77 Bn
4 Merck 364.95 Bn 327.95 Bn 13.19 Bn 2.47 Bn
5 Novartis Ag 311.58 Bn 285.16 Bn - 1.94 Bn
6 Astrazeneca 289.34 Bn 262.94 Bn 13.26 Bn 1.55 Bn
7 Amgen 251.64 Bn 203.30 Bn 7.58 Bn 541.00 Mn
8 Gilead Sciences 212.05 Bn 187.07 Bn 6.73 Bn 1.24 Bn
9 Pfizer 167.35 Bn 115.00 Bn 12.56 Bn 5.70 Bn
10 Spyre Therapeutics 9.40 Bn 5.68 Bn - 88.41 Mn
Historic Data

Historic Data

Download Data
DateValue
Sep 30, 2026 88.41 Mn
Jun 30, 2026 84.73 Mn
Mar 31, 2026 78.55 Mn
Dec 31, 2025 64.42 Mn
Sep 30, 2025 60.78 Mn
Jun 30, 2025 60.70 Mn
Mar 31, 2025 60.63 Mn
Dec 31, 2024 47.49 Mn
Sep 30, 2024 51.25 Mn
Jun 30, 2024 45.83 Mn
Mar 31, 2024 37.12 Mn
Dec 31, 2023 7.34 Mn
Sep 30, 2023 4.29 Mn
Jun 30, 2023 3.82 Mn
Mar 31, 2023 3.77 Mn
Dec 31, 2022 3.37 Mn
Sep 30, 2022 3.77 Mn
Jun 30, 2022 3.29 Mn
Mar 31, 2022 2.64 Mn
Dec 31, 2021 2.63 Mn
API Access

Spyre Therapeutics Shares Outstanding API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=shares-outstanding&ticker=SYRE&period=max&api_key=YOUR_API_KEY