Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026)
Spyre Therapeutics (SYRE) posted Shares Outstanding (Entity) of $2.6 million for Q1 2026, down 1.7% on a QoQ basis from $2.6 million in Q4 2025, and up 35.87% year-over-year from $1.9 million in Q1 2025.
Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026) Analysis & Trends
Spyre Therapeutics' Shares Outstanding (Entity) history runs 11 years deep, the most recent figure standing at $2.6 million for Q1 2026.
- Quarterly Shares Outstanding (Entity) rose 35.87% year-over-year to $2.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $2.6 million (up 35.87% YoY) and the FY2025 annual result came in at $2.6 million, up 4.02% from the prior year.
- Shares Outstanding (Entity) was $2.6 million for Q1 2026 at Spyre Therapeutics, down from $2.6 million in the prior quarter.
- Across five years, Shares Outstanding (Entity) topped out at $6.9 million in Q4 2023 and bottomed at $213900.0 in Q3 2025.
- A 5-year average of $2.9 million and a median of $2.9 million in 2022 frame the typical range for Shares Outstanding (Entity).
- Annual changes were most pronounced in 2023 — Shares Outstanding (Entity) surged 104.59% — and 2024, when it plunged 63.44%.
- Spyre Therapeutics' Shares Outstanding (Entity) stood at $3.4 million in 2022, then jumped by 104.59% to $6.9 million in 2023, then plunged by 63.44% to $2.5 million in 2024, then increased by 4.02% to $2.6 million in 2025, then fell by 1.7% to $2.6 million in 2026.
- Business Quant data shows SYRE's Shares Outstanding (Entity) at $2.6 million in Q1 2026, $2.6 million in Q4 2025, and $213900.0 in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares Outstanding (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | 6,012.74 Bn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | 47.82 Bn |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 1.44 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | 11.23 Bn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 254.10 Mn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 104.00 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | 400.00 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 62.19 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 198.10 Mn |
| 10 | Spyre Therapeutics | 257.83 Mn | 257.83 Mn | - | 2.58 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 2.58 Mn |
| Dec 31, 2025 | 2.62 Mn |
| Sep 30, 2025 | 213,900.00 |
| Jun 30, 2025 | 427,800.00 |
| Mar 31, 2025 | 1.90 Mn |
| Dec 31, 2024 | 2.52 Mn |
| Sep 30, 2024 | 50.89 Mn |
| Jun 30, 2024 | 45.32 Mn |
| Mar 31, 2024 | 36.51 Mn |
| Dec 31, 2023 | 6.90 Mn |
| Sep 30, 2023 | 4.29 Mn |
| Jun 30, 2023 | 3.82 Mn |
| Mar 31, 2023 | 3.77 Mn |
| Dec 31, 2022 | 3.37 Mn |
| Sep 30, 2022 | 3.77 Mn |
| Jun 30, 2022 | 3.29 Mn |
| Mar 31, 2022 | 2.64 Mn |
| Dec 31, 2021 | 2.63 Mn |
| Sep 30, 2021 | 2.63 Mn |
| Jun 30, 2021 | 2.63 Mn |