Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026)
Spyre Therapeutics (SYRE) recorded Shares Outstanding of 84.73 million in Q2 2026, up 39.6% from 60.7 million a year earlier and up 7.9% from the prior quarter.
Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026) Analysis & Trends
For FY2025, Spyre Therapeutics reported Shares Outstanding of 64.42 million, up 35.7% from FY2024.
- Annual Shares Outstanding has increased for nine straight years, with a five-year compound annual growth rate of 97.7% (FY2020 to FY2025).
- Across earlier years, Shares Outstanding came in at 47.49 million in FY2024 (+546.9%), 7.34 million in FY2023 (+117.7%), 3.37 million in FY2022 (+28.2%) and 2.63 million in FY2021 (+23.2%).
- The Q2 2026 figure is the highest quarterly Shares Outstanding in data going back to Q1 2015.
- On a year-over-year basis, Shares Outstanding has increased for seven consecutive quarters, with growth averaging 109.4% over the last seven quarters.
- Across the past five years, year-over-year growth in Shares Outstanding ran from 0.6% in Q1 2022 to 884.4% in Q1 2024.
- Per Business Quant, the preceding three quarters came in at 78.55 million (Q1 2026), 64.42 million (Q4 2025) and 60.78 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares Outstanding (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,082.65 Bn | 1,051.23 Bn | 19.71 Bn | 892.40 Mn |
| 2 | Johnson & Johnson | 623.68 Bn | 542.21 Bn | 17.26 Bn | 2.41 Bn |
| 3 | AbbVie | 459.43 Bn | 432.59 Bn | 12.70 Bn | 1.77 Bn |
| 4 | Merck | 354.80 Bn | 309.23 Bn | 12.21 Bn | 2.47 Bn |
| 5 | Novartis Ag | 269.16 Bn | 225.03 Bn | 11.24 Bn | 1.94 Bn |
| 6 | Astrazeneca | 244.40 Bn | 217.97 Bn | 12.86 Bn | 1.55 Bn |
| 7 | Amgen | 220.17 Bn | 175.57 Bn | 7.24 Bn | 540.00 Mn |
| 8 | Gilead Sciences | 183.05 Bn | 157.16 Bn | 6.22 Bn | 1.24 Bn |
| 9 | Pfizer | 160.27 Bn | 107.22 Bn | 10.94 Bn | 5.70 Bn |
| 10 | Spyre Therapeutics | 7.92 Bn | 7.92 Bn | - | 84.73 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 84.73 Mn |
| Mar 31, 2026 | 78.55 Mn |
| Dec 31, 2025 | 64.42 Mn |
| Sep 30, 2025 | 60.78 Mn |
| Jun 30, 2025 | 60.70 Mn |
| Mar 31, 2025 | 60.63 Mn |
| Dec 31, 2024 | 47.49 Mn |
| Sep 30, 2024 | 51.25 Mn |
| Jun 30, 2024 | 45.83 Mn |
| Mar 31, 2024 | 37.12 Mn |
| Dec 31, 2023 | 7.34 Mn |
| Sep 30, 2023 | 4.29 Mn |
| Jun 30, 2023 | 3.82 Mn |
| Mar 31, 2023 | 3.77 Mn |
| Dec 31, 2022 | 3.37 Mn |
| Sep 30, 2022 | 3.77 Mn |
| Jun 30, 2022 | 3.29 Mn |
| Mar 31, 2022 | 2.64 Mn |
| Dec 31, 2021 | 2.63 Mn |
| Sep 30, 2021 | 2.63 Mn |
Spyre Therapeutics Shares Outstanding API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=shares-outstanding&ticker=SYRE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "shares-outstanding", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=shares-outstanding&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();