Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026)

Spyre Therapeutics (SYRE) reported Shares Outstanding of $78.8 million for Q1 2026, up 30.8% on a YoY basis from $60.3 million in Q1 2025, and up 0.83% quarter-over-quarter from $78.2 million in Q4 2025.

Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026) Analysis & Trends

Spyre Therapeutics has reported Shares Outstanding for 12 years, with the latest figure at $78.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Shares Outstanding rose 30.8% year-over-year to $78.8 million; the trailing twelve-month figure through Mar 2026 stood at $78.8 million (up 30.8% YoY), and the FY2025 full-year result was $78.2 million, up 29.76% from the prior year.
  • Shares Outstanding for Q1 2026 stood at $78.8 million, up from $78.2 million in the prior quarter.
  • The five-year high for Shares Outstanding was $78.8 million in Q1 2026, with the low at $2.0 million in Q1 2022.
  • Historically, Shares Outstanding has averaged $34.9 million across 5 years, with a median of $36.6 million in 2024.
  • Annual changes were most pronounced in 2022 — Shares Outstanding plunged 95.97% — and 2024, when it surged 1467.38%.
  • Spyre Therapeutics' Shares Outstanding stood at $2.6 million in 2022, then surged by 1279.38% to $36.1 million in 2023, then surged by 67.12% to $60.3 million in 2024, then gained by 29.76% to $78.2 million in 2025, then increased by 0.83% to $78.8 million in 2026.
  • The last three Shares Outstanding figures came in at $78.8 million (Q1 2026), $78.2 million (Q4 2025), and $60.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares Outstanding (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - 400.00 Bn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - 91.57 Bn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -1.88
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 254.16 Mn
9 Abivax 90.15 Bn 90.15 Bn - -
10 Spyre Therapeutics 6.35 Bn 6.35 Bn - 78.84 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 78.84 Mn
Mar 31, 2026 78.84 Mn
Mar 31, 2026 78.84 Mn
Mar 31, 2026 78.84 Mn
Mar 31, 2026 78.84 Mn
Mar 31, 2026 78.84 Mn
Mar 31, 2026 78.84 Mn
Mar 31, 2026 78.84 Mn
Dec 31, 2025 78.19 Mn
Dec 31, 2025 78.19 Mn
Dec 31, 2025 78.19 Mn
Dec 31, 2025 78.19 Mn
Dec 31, 2025 78.19 Mn
Dec 31, 2025 78.19 Mn
Dec 31, 2025 78.19 Mn
Dec 31, 2025 78.19 Mn
Sep 30, 2025 60.47 Mn
Sep 30, 2025 60.47 Mn
Sep 30, 2025 60.47 Mn
Sep 30, 2025 60.47 Mn