Spyre Therapeutics (SYRE) Shares Outstanding (2014 - 2026)
Spyre Therapeutics (SYRE) recorded Weighted Average Shares Outstanding of 88.41 million in Q3 2026, up 45.5% from 60.78 million a year earlier and up 4.3% from the prior quarter.
Spyre Therapeutics (SYRE) Shares Outstanding (2014 - 2026) Analysis & Trends
For FY2025, Spyre Therapeutics reported Weighted Average Shares Outstanding of 64.42 million, up 35.7% from FY2024.
- Annual Weighted Average Shares Outstanding has a five-year compound annual growth rate of 3.8% (FY2020 to FY2025).
- Across earlier years, Weighted Average Shares Outstanding came in at 47.49 million in FY2024 (+546.9%), 7.34 million in FY2023 (-91.3%), 84.28 million in FY2022 (+28.2%) and 65.74 million in FY2021 (+23.2%).
- The Q3 2026 figure is the highest quarterly Weighted Average Shares Outstanding since Q2 2023.
- On a year-over-year basis, Weighted Average Shares Outstanding has increased for eight consecutive quarters, with growth averaging 101.4% over the last eight quarters.
- Peak year-over-year performance for Weighted Average Shares Outstanding in the last five years was growth of 546.9% in Q4 2024, against a decline of 95.4% in Q3 2023 at the low end.
- Per Business Quant, the preceding three quarters came in at 84.73 million (Q2 2026), 78.55 million (Q1 2026) and 64.42 million (Q4 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares Outstanding (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 891.90 Mn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 2.41 Bn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 1.77 Bn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 2.47 Bn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | 1.94 Bn |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 1.55 Bn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 541.00 Mn |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 1.24 Bn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 5.70 Bn |
| 10 | Spyre Therapeutics | 9.40 Bn | 5.68 Bn | - | 88.41 Mn |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 88.41 Mn |
| Jun 30, 2026 | 84.73 Mn |
| Mar 31, 2026 | 78.55 Mn |
| Dec 31, 2025 | 64.42 Mn |
| Sep 30, 2025 | 60.78 Mn |
| Jun 30, 2025 | 60.70 Mn |
| Mar 31, 2025 | 60.63 Mn |
| Dec 31, 2024 | 47.49 Mn |
| Sep 30, 2024 | 51.25 Mn |
| Jun 30, 2024 | 45.83 Mn |
| Mar 31, 2024 | 37.12 Mn |
| Dec 31, 2023 | 7.34 Mn |
| Sep 30, 2023 | 4.29 Mn |
| Jun 30, 2023 | 3.82 Mn |
| Mar 31, 2023 | 3.77 Mn |
| Dec 31, 2022 | 3.37 Mn |
| Sep 30, 2022 | 3.77 Mn |
| Jun 30, 2022 | 3.29 Mn |
| Mar 31, 2022 | 2.64 Mn |
| Dec 31, 2021 | 2.63 Mn |
Spyre Therapeutics Shares Outstanding API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=shares-outstanding&ticker=SYRE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "shares-outstanding", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=shares-outstanding&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();