Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026)
Spyre Therapeutics' (SYRE) quarterly Shares Outstanding (Entity) came in at $78.8 million in Q1 2026, up 30.8% YoY from $60.3 million in Q1 2025, and up 23.08% on a QoQ basis from $64.1 million in Q4 2025.
Analysis
Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026) Analysis & Trends
Spyre Therapeutics (SYRE) has 12 years of Shares Outstanding (Entity) data on file, last reported at $78.8 million in Q1 2026.
- Quarterly Shares Outstanding (Entity) rose 30.8% year-over-year to $78.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $78.8 million (up 30.8% YoY) and the FY2025 annual result came in at $64.1 million, up 36.21% from the prior year.
- Shares Outstanding (Entity) climbed to $78.8 million in Q1 2026, from $64.1 million in the prior quarter.
- In the past five years, Shares Outstanding (Entity) ranged from a high of $78.8 million in Q1 2026 to a low of $2.6 million in Q1 2022.
- A 5-year average of $31.8 million and a median of $36.6 million in 2024 frame the typical range for Shares Outstanding (Entity).
- Annual changes were most pronounced in 2023 — Shares Outstanding (Entity) retreated 1.47% — and 2024, when it soared 1467.34%.
- Tracing SYRE's Shares Outstanding (Entity) over 5 years: stood at $3.4 million in 2022, then surged by 104.59% to $6.9 million in 2023, then jumped by 581.85% to $47.0 million in 2024, then soared by 36.21% to $64.1 million in 2025, then advanced by 23.08% to $78.8 million in 2026.
- The last three Shares Outstanding (Entity) figures came in at $78.8 million (Q1 2026), $64.1 million (Q4 2025), and $60.5 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Shares Outstanding (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.62 Bn | 131.77 Bn | 2.84 Bn | 253.70 Mn |
| 2 | Regeneron Pharmaceuticals | 85.73 Bn | 77.73 Bn | 3.93 Bn | 102.80 Mn |
| 3 | Argenx Se | 63.53 Bn | 58.35 Bn | 1.37 Bn | 61.30 Mn |
| 4 | Moderna | 58.23 Bn | 53.09 Bn | 52.00 Mn | 398.00 Mn |
| 5 | Revolution Medicines | 44.05 Bn | 44.05 Bn | - | 210.89 Mn |
| 6 | BeOne Medicines | 40.03 Bn | 34.93 Bn | 1.53 Bn | 111.58 Mn |
| 7 | Alnylam Pharmaceuticals | 35.50 Bn | 32.19 Bn | 992.69 Mn | 133.61 Mn |
| 8 | Royalty Pharma | 28.52 Bn | 27.68 Bn | - | 445.06 Mn |
| 9 | Insmed | 27.46 Bn | 26.30 Bn | 358.27 Mn | 217.35 Mn |
| 10 | Spyre Therapeutics | 7.35 Bn | 7.35 Bn | - | 84.73 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 84.73 Mn |
| Mar 31, 2026 | 78.55 Mn |
| Dec 31, 2025 | 64.42 Mn |
| Sep 30, 2025 | 60.78 Mn |
| Jun 30, 2025 | 60.70 Mn |
| Mar 31, 2025 | 60.63 Mn |
| Dec 31, 2024 | 47.49 Mn |
| Sep 30, 2024 | 51.25 Mn |
| Jun 30, 2024 | 45.83 Mn |
| Mar 31, 2024 | 37.12 Mn |
| Dec 31, 2023 | 7.34 Mn |
| Sep 30, 2023 | 4.29 Mn |
| Jun 30, 2023 | 3.82 Mn |
| Mar 31, 2023 | 3.77 Mn |
| Dec 31, 2022 | 3.37 Mn |
| Sep 30, 2022 | 3.77 Mn |
| Jun 30, 2022 | 3.29 Mn |
| Mar 31, 2022 | 2.64 Mn |
| Dec 31, 2021 | 2.63 Mn |
| Sep 30, 2021 | 2.63 Mn |