Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026)

Spyre Therapeutics (SYRE) posted Shares Outstanding (Entity) of $2.6 million for Q1 2026, down 1.7% on a QoQ basis from $2.6 million in Q4 2025, and up 35.87% year-over-year from $1.9 million in Q1 2025.

Spyre Therapeutics (SYRE) Shares Outstanding (2015 - 2026) Analysis & Trends

Spyre Therapeutics' Shares Outstanding (Entity) history runs 11 years deep, the most recent figure standing at $2.6 million for Q1 2026.

  • Quarterly Shares Outstanding (Entity) rose 35.87% year-over-year to $2.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $2.6 million (up 35.87% YoY) and the FY2025 annual result came in at $2.6 million, up 4.02% from the prior year.
  • Shares Outstanding (Entity) was $2.6 million for Q1 2026 at Spyre Therapeutics, down from $2.6 million in the prior quarter.
  • Across five years, Shares Outstanding (Entity) topped out at $6.9 million in Q4 2023 and bottomed at $213900.0 in Q3 2025.
  • A 5-year average of $2.9 million and a median of $2.9 million in 2022 frame the typical range for Shares Outstanding (Entity).
  • Annual changes were most pronounced in 2023 — Shares Outstanding (Entity) surged 104.59% — and 2024, when it plunged 63.44%.
  • Spyre Therapeutics' Shares Outstanding (Entity) stood at $3.4 million in 2022, then jumped by 104.59% to $6.9 million in 2023, then plunged by 63.44% to $2.5 million in 2024, then increased by 4.02% to $2.6 million in 2025, then fell by 1.7% to $2.6 million in 2026.
  • Business Quant data shows SYRE's Shares Outstanding (Entity) at $2.6 million in Q1 2026, $2.6 million in Q4 2025, and $213900.0 in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares Outstanding (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 6,012.74 Bn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - 47.82 Bn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.44 Bn
4 NuCana 279.75 Bn 279.75 Bn - 11.23 Bn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 254.10 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 104.00 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - 400.00 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 62.19 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 198.10 Mn
10 Spyre Therapeutics 257.83 Mn 257.83 Mn - 2.58 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 2.58 Mn
Dec 31, 2025 2.62 Mn
Sep 30, 2025 213,900.00
Jun 30, 2025 427,800.00
Mar 31, 2025 1.90 Mn
Dec 31, 2024 2.52 Mn
Sep 30, 2024 50.89 Mn
Jun 30, 2024 45.32 Mn
Mar 31, 2024 36.51 Mn
Dec 31, 2023 6.90 Mn
Sep 30, 2023 4.29 Mn
Jun 30, 2023 3.82 Mn
Mar 31, 2023 3.77 Mn
Dec 31, 2022 3.37 Mn
Sep 30, 2022 3.77 Mn
Jun 30, 2022 3.29 Mn
Mar 31, 2022 2.64 Mn
Dec 31, 2021 2.63 Mn
Sep 30, 2021 2.63 Mn
Jun 30, 2021 2.63 Mn