Spyre Therapeutics (SYRE) Assets (2015 - 2026)
Spyre Therapeutics' (SYRE) quarterly Assets came in at $764.0 million in Q1 2026, up 34.08% YoY from $569.8 million in Q1 2025, and down 1.78% on a QoQ basis from $777.8 million in Q4 2025.
Analysis
Spyre Therapeutics (SYRE) Assets (2015 - 2026) Analysis & Trends
Spyre Therapeutics (SYRE) has 12 years of Assets data on file, last reported at $764.0 million in Q1 2026.
- Quarterly Assets rose 34.08% year-over-year to $764.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $764.0 million (up 34.08% YoY) and the FY2025 annual result came in at $777.8 million, up 27.82% from the prior year.
- Assets declined to $764.0 million in Q1 2026, from $777.8 million in the prior quarter.
- In the past five years, Assets ranged from a high of $777.8 million in Q4 2025 to a low of $52.5 million in Q1 2023.
- A 5-year average of $370.9 million and a median of $421.1 million in 2024 frame the typical range for Assets.
- Annual changes were most pronounced in 2022 — Assets plunged 49.17% — and 2024, when it surged 829.6%.
- Tracing SYRE's Assets over 5 years: stood at $71.1 million in 2022, then surged by 380.52% to $341.9 million in 2023, then surged by 77.99% to $608.5 million in 2024, then advanced by 27.82% to $777.8 million in 2025, then retreated by 1.78% to $764.0 million in 2026.
- The last three Assets figures came in at $764.0 million (Q1 2026), $777.8 million (Q4 2025), and $504.6 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Assets (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 27.42 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 41.73 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 10.03 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | 10.96 Bn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | 4.32 Bn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 9.18 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 5.56 Bn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 19.82 Bn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 2.10 Bn |
| 10 | Spyre Therapeutics | 7.53 Bn | 7.53 Bn | - | 1.17 Bn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 1.17 Bn |
| Mar 31, 2026 | 763.95 Mn |
| Dec 31, 2025 | 777.78 Mn |
| Sep 30, 2025 | 504.60 Mn |
| Jun 30, 2025 | 538.83 Mn |
| Mar 31, 2025 | 569.78 Mn |
| Dec 31, 2024 | 608.48 Mn |
| Sep 30, 2024 | 421.09 Mn |
| Jun 30, 2024 | 436.07 Mn |
| Mar 31, 2024 | 487.60 Mn |
| Dec 31, 2023 | 341.86 Mn |
| Sep 30, 2023 | 207.27 Mn |
| Jun 30, 2023 | 243.53 Mn |
| Mar 31, 2023 | 52.45 Mn |
| Dec 31, 2022 | 71.14 Mn |
| Sep 30, 2022 | 91.57 Mn |
| Jun 30, 2022 | 106.71 Mn |
| Mar 31, 2022 | 83.17 Mn |
| Dec 31, 2021 | 109.93 Mn |
| Sep 30, 2021 | 129.06 Mn |