Spyre Therapeutics (SYRE) Assets (2015 - 2026)

Spyre Therapeutics' (SYRE) quarterly Assets came in at $764.0 million in Q1 2026, up 34.08% YoY from $569.8 million in Q1 2025, and down 1.78% on a QoQ basis from $777.8 million in Q4 2025.

Spyre Therapeutics (SYRE) Assets (2015 - 2026) Analysis & Trends

Spyre Therapeutics (SYRE) has 12 years of Assets data on file, last reported at $764.0 million in Q1 2026.

  • Quarterly Assets rose 34.08% year-over-year to $764.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $764.0 million (up 34.08% YoY) and the FY2025 annual result came in at $777.8 million, up 27.82% from the prior year.
  • Assets declined to $764.0 million in Q1 2026, from $777.8 million in the prior quarter.
  • In the past five years, Assets ranged from a high of $777.8 million in Q4 2025 to a low of $52.5 million in Q1 2023.
  • A 5-year average of $370.9 million and a median of $421.1 million in 2024 frame the typical range for Assets.
  • Annual changes were most pronounced in 2022 — Assets plunged 49.17% — and 2024, when it surged 829.6%.
  • Tracing SYRE's Assets over 5 years: stood at $71.1 million in 2022, then surged by 380.52% to $341.9 million in 2023, then surged by 77.99% to $608.5 million in 2024, then advanced by 27.82% to $777.8 million in 2025, then retreated by 1.78% to $764.0 million in 2026.
  • The last three Assets figures came in at $764.0 million (Q1 2026), $777.8 million (Q4 2025), and $504.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Assets (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 27.42 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 41.73 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 10.03 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 4.32 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 9.18 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 15.59 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 19.82 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 5.56 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 2.10 Bn
10 Spyre Therapeutics 9.13 Bn 9.13 Bn - 1.17 Bn

Historic Data

Download Data
DateValue
Jun 30, 2026 1.17 Bn
Mar 31, 2026 763.95 Mn
Dec 31, 2025 777.78 Mn
Sep 30, 2025 504.60 Mn
Jun 30, 2025 538.83 Mn
Mar 31, 2025 569.78 Mn
Dec 31, 2024 608.48 Mn
Sep 30, 2024 421.09 Mn
Jun 30, 2024 436.07 Mn
Mar 31, 2024 487.60 Mn
Dec 31, 2023 341.86 Mn
Sep 30, 2023 207.27 Mn
Jun 30, 2023 243.53 Mn
Mar 31, 2023 52.45 Mn
Dec 31, 2022 71.14 Mn
Sep 30, 2022 91.57 Mn
Jun 30, 2022 106.71 Mn
Mar 31, 2022 83.17 Mn
Dec 31, 2021 109.93 Mn
Sep 30, 2021 129.06 Mn