Spyre Therapeutics (SYRE) Assets (2015 - 2026)

Spyre Therapeutics posted quarterly Assets of $764.0 million for Q1 2026, up 34.08% year-on-year from $569.8 million in Q1 2025, and down 1.78% on a QoQ basis from $777.8 million in Q4 2025.

Spyre Therapeutics (SYRE) has 12 years of Assets data on file, last reported at $764.0 million in Q1 2026.

  • For the quarter ending Q1 2026, Assets rose 34.08% year-over-year to $764.0 million; the trailing twelve-month figure through Mar 2026 stood at $764.0 million (up 34.08% YoY), and the FY2025 full-year result was $777.8 million, up 27.82% from the prior year.
  • Assets for Q1 2026 stood at $764.0 million, down from $777.8 million in the prior quarter.
  • Across five years, Assets topped out at $777.8 million in Q4 2025 and bottomed at $52.5 million in Q1 2023.
  • The 5-year median for Assets is $421.1 million (2024), against an average of $370.9 million.
  • The widest annual swing landed in 2022, when Assets slumped 49.17%; it then surged 829.6% in 2024.
  • A 5-year view of Assets shows it stood at $71.1 million in 2022, then soared by 380.52% to $341.9 million in 2023, then soared by 77.99% to $608.5 million in 2024, then climbed by 27.82% to $777.8 million in 2025, then decreased by 1.78% to $764.0 million in 2026.
  • The last three Assets figures came in at $764.0 million (Q1 2026), $777.8 million (Q4 2025), and $504.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Assets (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 14.93 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 37.37 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 1.73 Bn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - 78.88 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 33.89 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 26.48 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - 23.64 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 40.87 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 5.13 Bn
10 Spyre Therapeutics 5.55 Bn 5.55 Bn - 763.95 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 763.95 Mn
Dec 31, 2025 777.78 Mn
Sep 30, 2025 504.60 Mn
Jun 30, 2025 538.83 Mn
Mar 31, 2025 569.78 Mn
Dec 31, 2024 608.48 Mn
Sep 30, 2024 421.09 Mn
Jun 30, 2024 436.07 Mn
Mar 31, 2024 487.60 Mn
Dec 31, 2023 341.86 Mn
Sep 30, 2023 207.27 Mn
Jun 30, 2023 243.53 Mn
Mar 31, 2023 52.45 Mn
Dec 31, 2022 71.14 Mn
Sep 30, 2022 91.57 Mn
Jun 30, 2022 106.71 Mn
Mar 31, 2022 83.17 Mn
Dec 31, 2021 109.93 Mn
Sep 30, 2021 129.06 Mn
Jun 30, 2021 146.98 Mn
Mar 31, 2021 163.61 Mn
Dec 31, 2020 161.62 Mn
Sep 30, 2020 155.63 Mn
Jun 30, 2020 172.91 Mn
Mar 31, 2020 64.78 Mn
Dec 31, 2019 83.18 Mn
Sep 30, 2019 100.10 Mn
Jun 30, 2019 117.49 Mn
Mar 31, 2019 128.52 Mn
Dec 31, 2018 77.74 Mn
Sep 30, 2018 71.28 Mn
Jun 30, 2018 79.71 Mn
Mar 31, 2018 49.79 Mn
Dec 31, 2017 56.08 Mn
Sep 30, 2017 60.50 Mn
Jun 30, 2017 67.14 Mn
Mar 31, 2017 61.27 Mn
Dec 31, 2016 67.06 Mn
Sep 30, 2016 72.06 Mn
Jun 30, 2016 77.30 Mn
Mar 31, 2016 35.54 Mn
Dec 31, 2015 38.65 Mn