Spyre Therapeutics (SYRE) Assets (2015 - 2026)

Spyre Therapeutics (SYRE) posted Assets of $764.0 million for Q1 2026, down 1.78% on a QoQ basis from $777.8 million in Q4 2025, and up 34.08% year-over-year from $569.8 million in Q1 2025.

Spyre Therapeutics (SYRE) Assets (2015 - 2026) Analysis & Trends

Spyre Therapeutics' Assets history runs 12 years deep, the most recent figure standing at $764.0 million for Q1 2026.

  • Quarterly Assets rose 34.08% year-over-year to $764.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $764.0 million (up 34.08% YoY) and the FY2025 annual result came in at $777.8 million, up 27.82% from the prior year.
  • Assets was $764.0 million for Q1 2026 at Spyre Therapeutics, down from $777.8 million in the prior quarter.
  • Across five years, Assets topped out at $777.8 million in Q4 2025 and bottomed at $52.5 million in Q1 2023.
  • A 5-year average of $370.9 million and a median of $421.1 million in 2024 frame the typical range for Assets.
  • Annual changes were most pronounced in 2022 — Assets tumbled 49.17% — and 2024, when it surged 829.6%.
  • Spyre Therapeutics' Assets stood at $71.1 million in 2022, then jumped by 380.52% to $341.9 million in 2023, then jumped by 77.99% to $608.5 million in 2024, then grew by 27.82% to $777.8 million in 2025, then slipped by 1.78% to $764.0 million in 2026.
  • Business Quant data shows SYRE's Assets at $764.0 million in Q1 2026, $777.8 million in Q4 2025, and $504.6 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Assets (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 311.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - 78.88 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 8.55 Bn
4 NuCana 279.75 Bn 279.75 Bn - 39.68 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 26.48 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 40.87 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 811.27 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 10.03 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 2.25 Bn
10 Spyre Therapeutics 257.83 Mn 257.83 Mn - 763.95 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 763.95 Mn
Dec 31, 2025 777.78 Mn
Sep 30, 2025 504.60 Mn
Jun 30, 2025 538.83 Mn
Mar 31, 2025 569.78 Mn
Dec 31, 2024 608.48 Mn
Sep 30, 2024 421.09 Mn
Jun 30, 2024 436.07 Mn
Mar 31, 2024 487.60 Mn
Dec 31, 2023 341.86 Mn
Sep 30, 2023 207.27 Mn
Jun 30, 2023 243.53 Mn
Mar 31, 2023 52.45 Mn
Dec 31, 2022 71.14 Mn
Sep 30, 2022 91.57 Mn
Jun 30, 2022 106.71 Mn
Mar 31, 2022 83.17 Mn
Dec 31, 2021 109.93 Mn
Sep 30, 2021 129.06 Mn
Jun 30, 2021 146.98 Mn