Spyre Therapeutics (SYRE) Research & Development (2015 - 2026)
Spyre Therapeutics (SYRE) recorded Research & Development of $65.5 million in Q2 2026, up 63.2% from $40.15 million a year earlier and up 8.4% from the prior quarter.
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Analysis
Spyre Therapeutics (SYRE) Research & Development (2015 - 2026) Analysis & Trends
On a TTM basis, Spyre Therapeutics' Research & Development came in at $215.8 million as of Jun 30, 2026, up 21.9% year-over-year; for FY2025, it came in at $171.65 million, up 5.4% from FY2024.
- Annual Research & Development has increased for four straight years, with a five-year compound annual growth rate of 23.5% (FY2020 to FY2025).
- Across earlier years, Research & Development came in at $162.79 million in FY2024 (+81.9%), $89.5 million in FY2023 (+52.8%), $58.58 million in FY2022 (+2.6%) and $57.07 million in FY2021 (-4.3%).
- The Q2 2026 figure is the highest quarterly Research & Development in data going back to Q1 2015.
- On a year-over-year basis, Research & Development rose in seven of the last eight quarters, with growth averaging 33.9%.
- Peak year-over-year performance for Research & Development in the last five years was growth of 153.5% in Q1 2024, against a decline of 19.4% in Q3 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at $60.41 million (Q1 2026), $44.64 million (Q4 2025) and $45.25 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 3.65 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 2.34 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | 9.74 Bn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | -2.85 Bn |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | -4.05 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 1.87 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | 1.76 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 2.81 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 993.80 Mn |
| 10 | Spyre Therapeutics | 7.46 Bn | 7.46 Bn | - | 65.50 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 65.50 Mn |
| Mar 31, 2026 | 60.41 Mn |
| Dec 31, 2025 | 44.64 Mn |
| Sep 30, 2025 | 45.25 Mn |
| Jun 30, 2025 | 40.15 Mn |
| Mar 31, 2025 | 41.62 Mn |
| Dec 31, 2024 | 50.48 Mn |
| Sep 30, 2024 | 44.74 Mn |
| Jun 30, 2024 | 32.64 Mn |
| Mar 31, 2024 | 34.93 Mn |
| Dec 31, 2023 | 33.68 Mn |
| Sep 30, 2023 | 24.66 Mn |
| Jun 30, 2023 | 17.39 Mn |
| Mar 31, 2023 | 13.78 Mn |
| Dec 31, 2022 | 14.25 Mn |
| Sep 30, 2022 | 11.98 Mn |
| Jun 30, 2022 | 15.37 Mn |
| Mar 31, 2022 | 16.98 Mn |
| Dec 31, 2021 | 16.78 Mn |
| Sep 30, 2021 | 14.85 Mn |
API Access
Spyre Therapeutics Research & Development API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=research-and-development&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "research-and-development", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=research-and-development&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();