Spyre Therapeutics (SYRE) Research & Development (2015 - 2026)

Spyre Therapeutics (SYRE) has 12 years of Research & Development data on file, last reported at $60.4 million in Q1 2026.

• For the quarter ending Q1 2026, Research & Development rose 45.14% year-over-year to $60.4 million; the trailing twelve-month figure through Mar 2026 stood at $190.4 million (up 12.36% YoY), and the FY2025 full-year result was $171.7 million, up 5.44% from the prior year.
• Research & Development for Q1 2026 stood at $60.4 million, up from $44.6 million in the prior quarter.
• Across five years, Research & Development topped out at $60.4 million in Q1 2026 and bottomed at $12.0 million in Q3 2022.
• The 5-year median for Research & Development is $33.7 million (2023), against an average of $31.9 million.
• The widest annual swing landed in 2022, when Research & Development fell 19.36%; it then surged 153.54% in 2024.
• A 5-year view of Research & Development shows it stood at $14.3 million in 2022, then jumped by 136.35% to $33.7 million in 2023, then jumped by 49.88% to $50.5 million in 2024, then slipped by 11.58% to $44.6 million in 2025, then surged by 35.34% to $60.4 million in 2026.
• The last three Research & Development figures came in at $60.4 million (Q1 2026), $44.6 million (Q4 2025), and $45.2 million (Q3 2025), per Business Quant data.

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