Spyre Therapeutics SYRE Insider Ownership

NASDAQ SYRE
$87.44 +0.19 (+0.22%)
As of: Sep 4, 2026 · 11:50 AM EDT

Insider Holdings by Owner

5.14Mn Shares

Insider Ownership Statistics

as of 30 Sep, 2026
Insider Ownership
8.00%
0% pp QoQ
Shares Held by Insiders
4.83Mn
filed for Sep 2026
0.00% QoQ
Shares Outstanding
60.41Mn
60,414,223 shares
Direct Holdings
0
Indirect: 4.83Mn
Net Shares Traded (QoQ)
0
no net change in Sep 2026
Insiders Holding Shares
10
with Form 4 holdings on file

Shares Owned by Insiders

Shares held % of outstanding
Latest
Average ownership
Peak ownership

Shares Purchased/Sold by Insiders

Bought Sold
Latest quarter
Net over range
Buying quarters

Insider Ownership Summary

Quarter ending 30 Sep, 2026

Spyre Therapeutics's top three insider shareholders as of August 29, 2026 are Funds Management Llc Fairmount (Director, 4.02Mn shares), Funds Management Llc Fairmount (Director, 812.08K shares), Cameron Turtle (Chief Executive Officer, 567.54K shares).

Form 4 Holdings

Insiders Holding SYRE

Insiders 10
Shares held 5.14Mn
Of outstanding 8.51%
# Insider Position Direct Indirect Total Share of Insiders Last Filed
1 Funds Management Llc Fairmount Director 0 4,018,101 4,018,101 78.2% 25 Apr, 2024
2 Cameron Turtle Chief Executive Officer 567,540 0 567,540 11.0% 05 Aug, 2026
3 Jonathan Alspaugh Chief Financial Officer 165,372 0 165,372 3.2% 15 Mar, 2022
4 Armen Shanafelt Director 150,000 0 150,000 2.9% 13 Dec, 2021
5 Scott L Burrows Chief Financial Officer 97,994 0 97,994 1.9% 05 Aug, 2026
6 Michael Thomas Henderson Director 68,606 0 68,606 1.3% 23 Jun, 2026
7 Jr. Michael Conick Hanley Chief Commercial Officer 36,200 0 36,200 0.7% 10 Jun, 2022
8 Anthony G. Quinn President Ceo 22,022 0 22,022 0.4% 18 Mar, 2022
9 Jeffrey W. Albers Director 0 9,360 9,360 0.2% 10 Aug, 2026
10 Marcio Souza Director 3,600 0 3,600 0.1% 25 Aug, 2022

Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.

Form 4 Filings

626 Insider Transactions

Source SEC Form 4
Latest quarter Sep 2026
Download Data
Date Insider Position Transaction Shares Price Value Shares Held After Ownership
07 Aug, 2026 Jeffrey W. Albers Director Acquired M 5,000 $10.39 $51.95K 5,000 Direct
07 Aug, 2026 Jeffrey W. Albers Director Disposed S 5,000 $104.47 $522.35K 0 Direct
07 Aug, 2026 Jeffrey W. Albers Director Disposed S 8,000 $104.38 $835.04K 19,360 Indirect
07 Aug, 2026 Jeffrey W. Albers Director Disposed S 10,000 $104.68 $1.05Mn 9,360 Indirect
07 Aug, 2026 Jeffrey W. Albers Director Disposed M 5,000 $0.00 $0 45,000 Direct
03 Aug, 2026 Scott L Burrows Chief Financial Officer Acquired M 7,500 $14.50 $108.75K 105,494 Direct
03 Aug, 2026 Cameron Turtle Chief Executive Officer Disposed S 800 $93.97 $75.18K 581,740 Direct
03 Aug, 2026 Cameron Turtle Chief Executive Officer Disposed S 7,157 $95.10 $680.63K 574,583 Direct
03 Aug, 2026 Scott L Burrows Chief Financial Officer Disposed S 5,100 $95.21 $485.57K 100,394 Direct
03 Aug, 2026 Cameron Turtle Chief Executive Officer Disposed S 5,635 $95.93 $540.57K 568,948 Direct
03 Aug, 2026 Scott L Burrows Chief Financial Officer Disposed S 2,300 $96.30 $221.49K 98,094 Direct
03 Aug, 2026 Scott L Burrows Chief Financial Officer Disposed S 100 $97.10 $9.71K 97,994 Direct
03 Aug, 2026 Cameron Turtle Chief Executive Officer Disposed S 1,392 $96.82 $134.77K 567,556 Direct
03 Aug, 2026 Cameron Turtle Chief Executive Officer Disposed S 16 $97.46 $1.56K 567,540 Direct
03 Aug, 2026 Scott L Burrows Chief Financial Officer Disposed M 7,500 $0.00 $0 344,857 Direct
01 Jul, 2026 Scott L Burrows Chief Financial Officer Acquired M 7,500 $14.50 $108.75K 105,494 Direct
01 Jul, 2026 Cameron Turtle Chief Executive Officer Disposed S 10,176 $87.44 $889.79K 587,364 Direct
01 Jul, 2026 Sheldon Sloan Chief Medical Officer Acquired M 8,334 $27.46 $228.85K 8,334 Direct
01 Jul, 2026 Sheldon Sloan Chief Medical Officer Disposed S 6,500 $87.52 $568.88K 1,834 Direct
01 Jul, 2026 Scott L Burrows Chief Financial Officer Disposed S 5,775 $87.55 $505.60K 99,719 Direct