Spyre Therapeutics, Inc. (SYRE) Insider Ownership

Historic Ownership Trends

There are no significant Insider Shareholders in Spyre Therapeutics as of December 12, 2025.

Top Direct Holders

Insider ownership data is derived from the last 60 months of Form 4 SEC filings.
Holder Position Shares Report Date
Funds Management Llc Fairmount 4,018,101 25 Apr, 2024
Cameron Turtle Chief Executive Officer 686,907 03 Dec, 2025
Anthony G. Quinn President & CEO 22,022 18 Mar, 2022
Jonathan Alspaugh Chief Financial Officer 6,615 15 Mar, 2022
Armen Shanafelt 6,000 13 Dec, 2021
Michael Thomas Henderson 105,379 14 Jan, 2025
Scott L Burrows Chief Financial Officer 97,994 03 Sep, 2025
Marcio Souza 3,600 25 Aug, 2022
Jr. Michael Conick Hanley Chief Commercial Officer 1,448 10 Jun, 2022
Jeffrey W. Albers 27,360 08 Nov, 2024

* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.

Recent Insider Transactions

Detailed insider trading activity based on Form 4 SEC filings.
Download Data
Transaction Date Insider Name Security Class Transaction Type Shares Traded Price Shares Remaining Ownership Code
01 Dec, 2025 Cameron Turtle Common Stock D 10,995 $28.73 690,912 D S
01 Dec, 2025 Cameron Turtle Common Stock D 4,005 $29.83 686,907 D S
03 Nov, 2025 Cameron Turtle Common Stock D 28,155 $23.13 718,752 D S
03 Nov, 2025 Cameron Turtle Common Stock D 16,845 $23.66 701,907 D S
02 Sep, 2025 Scott L Burrows Common Stock D 18,428 $16.26 97,994 D S
02 Sep, 2025 Scott L Burrows - - 97,994 D
10 Jan, 2025 Michael Thomas Henderson - - 105,379 D
10 Jan, 2025 Michael Thomas Henderson Common Stock A 105,379 $0.00 105,379 D J
06 Nov, 2024 Jeffrey W. Albers Common Stock D 6,700 $36.76 27,360 I S
25 Oct, 2024 Jeffrey W. Albers Common Stock D 300 $36.43 34,060 I S
25 Oct, 2024 Jeffrey W. Albers - - 34,060 I
03 Sep, 2024 Scott L Burrows Common Stock D 18,531 $28.17 116,422 D S
03 Sep, 2024 Scott L Burrows - - 116,422 D
25 Apr, 2024 Funds Management Llc Fairmount Common Stock A 3,639,680 $0.00 4,018,101 I M
25 Apr, 2024 Funds Management Llc Fairmount - - 4,018,101 I
15 Feb, 2024 Cameron Turtle - - 746,907 D
15 Feb, 2024 Cameron Turtle Common Stock A 400 $9.82 746,907 D A
29 Dec, 2023 Funds Management Llc Fairmount Common Stock D 3,435,480 $0.00 0 I J
29 Dec, 2023 Funds Management Llc Fairmount Common Stock A 406,038 $0.00 406,038 I J
29 Dec, 2023 Funds Management Llc Fairmount - - 406,038 I