Spyre Therapeutics SYRE Insider Ownership

NASDAQ SYRE
$84.72 -1.07 (-1.25%)
At close: Sep 29, 2026 · 4:00 PM EDT

Insider Holdings by Owner

1.56Mn Shares

Insider Ownership Statistics

as of 30 Sep, 2026
Insider Ownership
1.85%
▼-0.093% pp QoQ
Shares Held by Insiders
1.56Mn
filed for Sep 2026
▼-4.77% QoQ
Shares Outstanding
84.73Mn
84,729,435 shares
Direct Holdings
743.44K
Indirect: 821.44K
Net Shares Traded (QoQ)
-78.39K
net selling in Sep 2026
Insiders Holding Shares
11
with Form 4 holdings on file

Shares Owned by Insiders

Shares held % of outstanding
Latest —
Average ownership —
Peak ownership —

Shares Purchased/Sold by Insiders

Bought Sold
Latest quarter —
Net over range —
Buying quarters —

Insider Ownership Summary

Quarter ending 30 Sep, 2026

As of September 29, 2026, the three largest insider holders of SYRE are Funds Management Llc Fairmount (Director, 812.08K shares), Cameron Turtle (Chief Executive Officer, 552.54K shares), Scott L Burrows (Chief Financial Officer, 79.76K shares).

Form 4 Holdings

Insiders Holding SYRE

Insiders 11
Shares held 1.56Mn
Of outstanding 1.85%
# Insider Position Direct Indirect Total Share of Insiders Last Filed
1 Funds Management Llc Fairmount Director, TenPercentOwner 0 812,076 812,076 51.9% 29 Dec, 2023
2 Cameron Turtle Chief Executive Officer 552,540 0 552,540 35.3% 03 Sep, 2026
3 Scott L Burrows Chief Financial Officer 79,762 0 79,762 5.1% 03 Sep, 2026
4 Michael Thomas Henderson Director 68,606 0 68,606 4.4% 23 Jun, 2026
5 Anthony G. Quinn President Ceo 22,022 0 22,022 1.4% 18 Mar, 2022
6 Jeffrey W. Albers Director 0 9,360 9,360 0.6% 10 Aug, 2026
7 Jonathan Alspaugh Chief Financial Officer 6,615 0 6,615 0.4% 15 Mar, 2022
8 Armen Shanafelt Director 6,000 0 6,000 0.4% 13 Dec, 2021
9 Marcio Souza Director 3,600 0 3,600 0.2% 25 Aug, 2022
10 Heidy King-Jones Officer 2,845 0 2,845 0.2% 03 Sep, 2026
11 Jr. Michael Conick Hanley Chief Commercial Officer 1,448 0 1,448 0.1% 10 Jun, 2022

Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.

Form 4 Filings

384 Insider Transactions

Source SEC Form 4
Latest quarter Sep 2026
Download Data
Date Insider Position Transaction Shares Price Value Shares Held After Ownership
01 Sep, 2026 Cameron Turtle Chief Executive Officer Disposed S 2,500 $86.36 $215.90K 565,040 Direct
01 Sep, 2026 Heidy King-Jones Officer Acquired M 27,999 $14.50 $405.99K 30,844 Direct
01 Sep, 2026 Scott L Burrows Chief Financial Officer Acquired M 7,500 $14.50 $108.75K 105,494 Direct
01 Sep, 2026 Scott L Burrows Chief Financial Officer Disposed S 900 $86.25 $77.63K 104,594 Direct
01 Sep, 2026 Cameron Turtle Chief Executive Officer Disposed S 8,400 $87.15 $732.06K 556,640 Direct
01 Sep, 2026 Heidy King-Jones Officer Disposed S 4,845 $86.40 $418.61K 25,999 Direct
01 Sep, 2026 Scott L Burrows Chief Financial Officer Disposed S 4,384 $87.11 $381.89K 100,210 Direct
01 Sep, 2026 Heidy King-Jones Officer Disposed S 16,548 $87.20 $1.44Mn 9,451 Direct
01 Sep, 2026 Cameron Turtle Chief Executive Officer Disposed S 3,700 $88.06 $325.82K 552,940 Direct
01 Sep, 2026 Cameron Turtle Chief Executive Officer Disposed S 400 $89.07 $35.63K 552,540 Direct
01 Sep, 2026 Heidy King-Jones Officer Disposed S 6,206 $88.17 $547.18K 3,245 Direct
01 Sep, 2026 Scott L Burrows Chief Financial Officer Disposed S 2,016 $88.03 $177.47K 98,194 Direct
01 Sep, 2026 Scott L Burrows Chief Financial Officer Disposed S 200 $89.04 $17.81K 97,994 Direct
01 Sep, 2026 Heidy King-Jones Officer Disposed S 400 $89.38 $35.75K 2,845 Direct
02 Sep, 2026 Scott L Burrows Chief Financial Officer Disposed S 18,232 $89.35 $1.63Mn 79,762 Direct
02 Sep, 2026 Heidy King-Jones Officer Acquired M 400 $14.50 $5.80K 3,245 Direct
01 Sep, 2026 Scott L Burrows Chief Financial Officer Disposed M 7,500 $0.00 $0 337,357 Direct
02 Sep, 2026 Heidy King-Jones Officer Disposed S 400 $90.00 $36.00K 2,845 Direct
01 Sep, 2026 Heidy King-Jones Officer Disposed M 27,999 $0.00 $0 511,811 Direct
02 Sep, 2026 Heidy King-Jones Officer Disposed M 400 $0.00 $0 511,411 Direct