Spyre Therapeutics (SYRE) EBIT (2015 - 2026)
Spyre Therapeutics' EBIT came in at -$41.64 million for Q2 2026, compared with -$41.94 million a year earlier.
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Analysis
Spyre Therapeutics (SYRE) EBIT (2015 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Spyre Therapeutics reported EBIT of -$201.34 million; for FY2025, it came in at -$209.56 million.
- Going back by year, EBIT was -$208.57 million in FY2024, -$242.3 million in FY2023, -$84.78 million in FY2022 and -$65.65 million in FY2021.
- The Q2 2026 figure represents the highest quarterly EBIT since Q3 2023.
- Business Quant data shows SYRE's EBIT at -$45.64 million (Q1 2026), -$57.17 million (Q4 2025) and -$56.89 million (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 7.14 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 6.43 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -584.00 Mn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 4.75 Bn |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 3.16 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 3.51 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -10.39 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 4.27 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 1.25 Bn |
| 10 | Spyre Therapeutics | 7.46 Bn | 7.46 Bn | - | -41.64 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -41.64 Mn |
| Mar 31, 2026 | -45.64 Mn |
| Dec 31, 2025 | -57.17 Mn |
| Sep 30, 2025 | -56.89 Mn |
| Jun 30, 2025 | -41.94 Mn |
| Mar 31, 2025 | -53.57 Mn |
| Dec 31, 2024 | -61.25 Mn |
| Sep 30, 2024 | -55.39 Mn |
| Jun 30, 2024 | -44.15 Mn |
| Mar 31, 2024 | -47.77 Mn |
| Dec 31, 2023 | -45.91 Mn |
| Sep 30, 2023 | -18.34 Mn |
| Jun 30, 2023 | -159.25 Mn |
| Mar 31, 2023 | -18.81 Mn |
| Dec 31, 2022 | -19.16 Mn |
| Sep 30, 2022 | -18.76 Mn |
| Jun 30, 2022 | -22.42 Mn |
| Mar 31, 2022 | -24.44 Mn |
| Dec 31, 2021 | -20.44 Mn |
| Sep 30, 2021 | -20.29 Mn |
API Access
Spyre Therapeutics EBIT API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebit&ticker=SYRE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebit", "ticker": "SYRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebit&ticker=SYRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();