Spyre Therapeutics (SYRE) Tax Rate (2021 - 2025)

Spyre Therapeutics posted quarterly Tax Rate of 0.03% for Q1 2025, up 11.0% year-on-year from 0.03% in Q1 2024, and up 1985.38% on a QoQ basis from 0.0% in Q4 2024.

Spyre Therapeutics (SYRE) has 5 years of Tax Rate data on file, last reported at 0.03% in Q1 2025.

  • For the quarter ending Q1 2025, Tax Rate rose 11.0% year-over-year to 0.03%; the trailing twelve-month figure through Dec 2025 stood at 0.01% (up 3.0% YoY), and the FY2025 full-year result was 0.01%, up 3.0% from the prior year.
  • Tax Rate for Q1 2025 stood at 0.03%, up from 0.0% in the prior quarter.
  • Across five years, Tax Rate topped out at 1.13% in Q3 2022 and bottomed at 1.37% in Q2 2021.
  • The 5-year median for Tax Rate is 0.03% (2024), against an average of 0.05%.
  • The widest annual swing landed in 2022, when Tax Rate soared 133 bps; it then tumbled 114 bps in 2023.
  • A 5-year view of Tax Rate shows it stood at 0.11% in 2021, then plunged by 80 bps to 0.2% in 2022, then soared by 96 bps to 0.01% in 2023, then surged by 76 bps to 0.0% in 2024, then soared by 1985 bps to 0.03% in 2025.
  • The last three Tax Rate figures came in at 0.03% (Q1 2025), 0.0% (Q4 2024), and 0.03% (Q3 2024), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Tax Rate (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 57.14
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 5.61
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 17.68
7 Evaxion A 62.56 Bn 62.54 Bn - -6.79
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 12.51
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 7.07
10 Spyre Therapeutics 5.55 Bn 5.55 Bn - -

Historic Data

Download Data 🔒
DateValue
Mar 31, 2025 0.03
Mar 31, 2025 0.03
Dec 31, 2024 0.00
Dec 31, 2024 0.00
Sep 30, 2024 -0.03
Sep 30, 2024 -0.03
Mar 31, 2024 -0.07
Mar 31, 2024 -0.07
Sep 30, 2023 -0.01
Sep 30, 2023 -0.01
Jun 30, 2023 0.00
Jun 30, 2023 0.00
Mar 31, 2023 0.20
Mar 31, 2023 0.20
Dec 31, 2022 -0.20
Dec 31, 2022 -0.20
Sep 30, 2022 1.13
Sep 30, 2022 1.13
Jun 30, 2022 -0.04
Jun 30, 2022 -0.04
Dec 31, 2021 -0.11
Dec 31, 2021 -0.11
Sep 30, 2021 -0.13
Sep 30, 2021 -0.13
Jun 30, 2021 -1.37
Jun 30, 2021 -1.37