Spyre Therapeutics (SYRE) Tax Rate (2021 - 2025)

Spyre Therapeutics (SYRE) reported Tax Rate of 0.03% for Q1 2025, up 11.0% on a YoY basis from 0.03% in Q1 2024, and up 1985.38% quarter-over-quarter from 0.0% in Q4 2024.

Spyre Therapeutics (SYRE) Tax Rate (2021 - 2025) Analysis & Trends

Spyre Therapeutics has reported Tax Rate for 5 years, with the latest figure at 0.03% in Q1 2025.

  • For the quarter ending Q1 2025, Tax Rate rose 11.0% year-over-year to 0.03%; the trailing twelve-month figure through Dec 2025 stood at 0.01% (up 3.0% YoY), and the FY2025 full-year result was 0.01%, up 3.0% from the prior year.
  • Tax Rate for Q1 2025 stood at 0.03%, up from 0.0% in the prior quarter.
  • The five-year high for Tax Rate was 1.13% in Q3 2022, with the low at 1.37% in Q2 2021.
  • Historically, Tax Rate has averaged 0.05% across 5 years, with a median of 0.03% in 2024.
  • Annual changes were most pronounced in 2022 — Tax Rate soared 133 bps — and 2023, when it sank 114 bps.
  • Spyre Therapeutics' Tax Rate stood at 0.11% in 2021, then sank by 80 bps to 0.2% in 2022, then surged by 96 bps to 0.01% in 2023, then jumped by 76 bps to 0.0% in 2024, then surged by 1985 bps to 0.03% in 2025.
  • The last three Tax Rate figures came in at 0.03% (Q1 2025), 0.0% (Q4 2024), and 0.03% (Q3 2024), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Tax Rate (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -57.14
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -6.79
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 5.61
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 17.68
9 Abivax 91.96 Bn 91.96 Bn - -
10 Spyre Therapeutics 6.95 Bn 6.95 Bn - -

Historic Data

Download Data
DateValue
Mar 31, 2025 0.03%
Mar 31, 2025 0.03%
Dec 31, 2024 0.00%
Dec 31, 2024 0.00%
Sep 30, 2024 -0.03%
Sep 30, 2024 -0.03%
Mar 31, 2024 -0.07%
Mar 31, 2024 -0.07%
Sep 30, 2023 -0.01%
Sep 30, 2023 -0.01%
Jun 30, 2023 0.00%
Jun 30, 2023 0.00%
Mar 31, 2023 0.20%
Mar 31, 2023 0.20%
Dec 31, 2022 -0.20%
Dec 31, 2022 -0.20%
Sep 30, 2022 1.13%
Sep 30, 2022 1.13%
Jun 30, 2022 -0.04%
Jun 30, 2022 -0.04%