Spyre Therapeutics (SYRE) Tax Rate (2021 - 2025)

Spyre Therapeutics' (SYRE) quarterly Tax Rate came in at 0.03% in Q1 2025, up 11.0% YoY from 0.03% in Q1 2024, and up 1985.38% on a QoQ basis from 0.0% in Q4 2024.

Spyre Therapeutics (SYRE) Tax Rate (2021 - 2025) Analysis & Trends

Spyre Therapeutics (SYRE) has 5 years of Tax Rate data on file, last reported at 0.03% in Q1 2025.

  • Quarterly Tax Rate rose 11.0% year-over-year to 0.03% in Q1 2025, while the trailing twelve-month figure through Dec 2025 was 0.01% (up 3.0% YoY) and the FY2025 annual result came in at 0.01%, up 3.0% from the prior year.
  • Tax Rate rose to 0.03% in Q1 2025, from 0.0% in the prior quarter.
  • In the past five years, Tax Rate ranged from a high of 1.13% in Q3 2022 to a low of 1.37% in Q2 2021.
  • A 5-year average of 0.05% and a median of 0.03% in 2024 frame the typical range for Tax Rate.
  • Annual changes were most pronounced in 2022 — Tax Rate soared 133 bps — and 2023, when it sank 114 bps.
  • Tracing SYRE's Tax Rate over 5 years: stood at 0.11% in 2021, then sank by 80 bps to 0.2% in 2022, then surged by 96 bps to 0.01% in 2023, then jumped by 76 bps to 0.0% in 2024, then surged by 1985 bps to 0.03% in 2025.
  • The last three Tax Rate figures came in at 0.03% (Q1 2025), 0.0% (Q4 2024), and 0.03% (Q3 2024), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Tax Rate (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 20.98%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 15.11%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 10.91%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 24.15%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -9.47%
7 Royalty Pharma 33.72 Bn 35.84 Bn - -
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 7.49%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -16.71%
10 Spyre Therapeutics 9.13 Bn 9.13 Bn - -

Historic Data

Download Data
DateValue
Mar 31, 2025 0.03%
Mar 31, 2025 0.03%
Mar 31, 2025 0.03%
Dec 31, 2024 0.00%
Dec 31, 2024 0.00%
Dec 31, 2024 0.00%
Sep 30, 2024 -0.03%
Sep 30, 2024 -0.03%
Sep 30, 2024 -0.03%
Mar 31, 2024 -0.07%
Mar 31, 2024 -0.07%
Mar 31, 2024 -0.07%
Sep 30, 2023 -0.01%
Sep 30, 2023 -0.01%
Sep 30, 2023 -0.01%
Jun 30, 2023 0.00%
Jun 30, 2023 0.00%
Jun 30, 2023 0.00%
Mar 31, 2023 0.20%
Mar 31, 2023 0.20%