Spyre Therapeutics (SYRE) Debt to Equity (2023 - 2026)
Spyre Therapeutics (SYRE) reported Debt to Equity of $0.07 for Q1 2026, down 15.54% on a YoY basis from $0.09 in Q1 2025, and up 134.83% quarter-over-quarter from $0.03 in Q4 2025.
Spyre Therapeutics (SYRE) Debt to Equity (2023 - 2026) Analysis & Trends
Spyre Therapeutics has reported Debt to Equity for 4 years, with the latest figure at $0.07 in Q1 2026.
- For the quarter ending Q1 2026, Debt to Equity fell 15.54% year-over-year to $0.07; the trailing twelve-month figure through Mar 2026 stood at $0.07 (down 15.54% YoY), and the FY2025 full-year result was $0.03, down 34.13% from the prior year.
- Debt to Equity for Q1 2026 stood at $0.07, up from $0.03 in the prior quarter.
- The five-year high for Debt to Equity was $0.13 in Q2 2025, with the low at -$0.79 in Q2 2023.
- Historically, Debt to Equity has averaged -$0.03 across 4 years, with a median of $0.03 in 2025.
- The largest YoY upside for Debt to Equity was 1763.77% in 2025 against a maximum downside of 67.96% in 2025.
- Spyre Therapeutics' Debt to Equity stood at $0.01 in 2023, then jumped by 541.21% to $0.05 in 2024, then sank by 34.13% to $0.03 in 2025, then soared by 134.83% to $0.07 in 2026.
- The last three Debt to Equity figures came in at $0.07 (Q1 2026), $0.03 (Q4 2025), and $0.02 (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Debt/Equity (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | - |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | 0.32 |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | - |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | - |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | - |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | - |
| 10 | Spyre Therapeutics | 6.35 Bn | 6.35 Bn | - | 0.07 |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 0.07 |
| Dec 31, 2025 | 0.03 |
| Sep 30, 2025 | 0.02 |
| Jun 30, 2025 | 0.13 |
| Mar 31, 2025 | 0.09 |
| Dec 31, 2024 | 0.05 |
| Sep 30, 2024 | 0.08 |
| Jun 30, 2024 | 0.01 |
| Mar 31, 2024 | 0.02 |
| Dec 31, 2023 | 0.01 |
| Sep 30, 2023 | -0.03 |
| Jun 30, 2023 | -0.79 |