Spyre Therapeutics (SYRE) Share-based Compensation (2015 - 2026)

Spyre Therapeutics (SYRE) reported Share-based Compensation of $12.8 million for Q1 2026, up 44.55% on a YoY basis from $8.9 million in Q1 2025, and up 30.53% quarter-over-quarter from $9.8 million in Q4 2025.

Spyre Therapeutics (SYRE) Share-based Compensation (2015 - 2026) Analysis & Trends

Spyre Therapeutics has reported Share-based Compensation for 12 years, with the latest figure at $12.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Share-based Compensation rose 44.55% year-over-year to $12.8 million; the trailing twelve-month figure through Mar 2026 stood at $41.6 million (up 4.23% YoY), and the FY2025 full-year result was $37.6 million, down 16.1% from the prior year.
  • Share-based Compensation for Q1 2026 stood at $12.8 million, up from $9.8 million in the prior quarter.
  • The five-year high for Share-based Compensation was $17.3 million in Q4 2023, with the low at $1.4 million in Q4 2022.
  • Historically, Share-based Compensation has averaged $7.9 million across 5 years, with a median of $9.0 million in 2024.
  • Annual changes were most pronounced in 2023 — Share-based Compensation jumped 1110.23% — and 2024, when it sank 46.64%.
  • Spyre Therapeutics' Share-based Compensation stood at $1.4 million in 2022, then jumped by 1110.23% to $17.3 million in 2023, then tumbled by 46.64% to $9.2 million in 2024, then climbed by 6.46% to $9.8 million in 2025, then soared by 30.53% to $12.8 million in 2026.
  • The last three Share-based Compensation figures came in at $12.8 million (Q1 2026), $9.8 million (Q4 2025), and $9.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Share-based Compensation (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - 305,000.00
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 166.40 Mn
9 Abivax 90.15 Bn 90.15 Bn - 26.47 Mn
10 Spyre Therapeutics 6.35 Bn 6.35 Bn - 12.81 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 12.81 Mn
Mar 31, 2026 12.81 Mn
Dec 31, 2025 9.81 Mn
Dec 31, 2025 9.81 Mn
Sep 30, 2025 9.57 Mn
Sep 30, 2025 9.57 Mn
Jun 30, 2025 9.38 Mn
Jun 30, 2025 9.38 Mn
Mar 31, 2025 8.86 Mn
Mar 31, 2025 8.86 Mn
Dec 31, 2024 9.22 Mn
Dec 31, 2024 9.22 Mn
Sep 30, 2024 13.10 Mn
Sep 30, 2024 13.10 Mn
Jun 30, 2024 8.70 Mn
Jun 30, 2024 8.70 Mn
Mar 31, 2024 13.80 Mn
Mar 31, 2024 13.80 Mn
Dec 31, 2023 17.27 Mn
Dec 31, 2023 17.27 Mn