Spyre Therapeutics (SYRE) Income from Continuing Operations (2015 - 2026)

Spyre Therapeutics (SYRE) posted Income from Continuing Operations of 69005000.0 for Q1 2026, down 10.36% on a QoQ basis from 62530000.0 in Q4 2025, and down 54.12% year-over-year from 150409467.16 in Q1 2025.

Spyre Therapeutics (SYRE) Income from Continuing Operations (2015 - 2026) Analysis & Trends

Spyre Therapeutics' Income from Continuing Operations history runs 12 years deep, the most recent figure standing at 69005000.0 for Q1 2026.

  • Quarterly Income from Continuing Operations fell 54.12% year-over-year to 69005000.0 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 179435000.0 (up 14.12% YoY) and the FY2025 annual result came in at 155203000.0, up 25.39% from the prior year.
  • Income from Continuing Operations was 69005000.0 for Q1 2026 at Spyre Therapeutics, down from 62530000.0 in the prior quarter.
  • Across five years, Income from Continuing Operations topped out at 11183000.0 in Q3 2025 and bottomed at 217081000.0 in Q2 2023.
  • A 5-year average of 50284176.47 and a median of 40107000.0 in 2023 frame the typical range for Income from Continuing Operations.
  • Annual changes were most pronounced in 2023 — Income from Continuing Operations plunged 872.45% — and 2025, when it surged 83.8%.
  • Spyre Therapeutics' Income from Continuing Operations stood at 18822000.0 in 2022, then plunged by 235.67% to 63180000.0 in 2023, then grew by 10.9% to 56296000.0 in 2024, then dropped by 11.07% to 62530000.0 in 2025, then fell by 10.36% to 69005000.0 in 2026.
  • Business Quant data shows SYRE's Income from Continuing Operations at 69005000.0 in Q1 2026, 62530000.0 in Q4 2025, and 11183000.0 in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Income (Continuing) (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -37.09 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 227.36 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.68 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 727.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 362.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Spyre Therapeutics 257.83 Mn 257.83 Mn - -69.01 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -69.01 Mn
Dec 31, 2025 -62.53 Mn
Sep 30, 2025 -11.18 Mn
Jun 30, 2025 -36.72 Mn
Mar 31, 2025 -44.77 Mn
Dec 31, 2024 -56.30 Mn
Sep 30, 2024 -69.03 Mn
Jun 30, 2024 -38.84 Mn
Mar 31, 2024 -43.86 Mn
Dec 31, 2023 -63.18 Mn
Sep 30, 2023 -40.11 Mn
Jun 30, 2023 -217.08 Mn
Mar 31, 2023 -18.42 Mn
Dec 31, 2022 -18.82 Mn
Sep 30, 2022 -18.23 Mn
Jun 30, 2022 -22.32 Mn
Mar 31, 2022 -24.44 Mn
Dec 31, 2021 -20.45 Mn
Sep 30, 2021 -20.31 Mn
Jun 30, 2021 -6.83 Mn