Karyopharm Therapeutics (KPTI) Tax Provisions (2017 - 2025)

Karyopharm Therapeutics (KPTI) reported Tax Provisions of -$67000.0 for Q4 2025, up 38.53% on a YoY basis from -$48364.2 in Q4 2024, and down 297.06% quarter-over-quarter from $34000.0 in Q3 2025.

Karyopharm Therapeutics (KPTI) Tax Provisions (2017 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Tax Provisions for 9 years, with the latest figure at -$67000.0 in Q4 2025.

  • For the quarter ending Q4 2025, Tax Provisions rose 38.53% year-over-year to -$67000.0; the trailing twelve-month figure through Dec 2025 stood at $43000.0 (down 24.56% YoY), and the FY2025 full-year result was $43000.0, down 24.56% from the prior year.
  • Tax Provisions for Q4 2025 stood at -$67000.0, down from $34000.0 in the prior quarter.
  • The five-year high for Tax Provisions was $149000.0 in Q1 2021, with the low at -$121000.0 in Q4 2021.
  • Historically, Tax Provisions has averaged $51850.0 across 5 years, with a median of $60500.0 in 2023.
  • Annual changes were most pronounced in 2021 — Tax Provisions sank 295.16% — and 2022, when it jumped 160.33%.
  • Karyopharm Therapeutics' Tax Provisions stood at -$121000.0 in 2021, then jumped by 160.33% to $73000.0 in 2022, then surged by 46.58% to $107000.0 in 2023, then slumped by 201.87% to -$109000.0 in 2024, then jumped by 38.53% to -$67000.0 in 2025.
  • The last three Tax Provisions figures came in at -$67000.0 (Q4 2025), $34000.0 (Q3 2025), and $40000.0 (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Taxes (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -11.20 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -859,000.00
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - 216,000.00
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 221.50 Mn
9 Abivax 91.71 Bn 91.71 Bn - -
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn -67,000.00

Historic Data

Download Data
DateValue
Dec 31, 2025 -67,000.00
Sep 30, 2025 34,000.00
Jun 30, 2025 40,000.00
Mar 31, 2025 36,000.00
Dec 31, 2024 -109,000.00
Sep 30, 2024 28,000.00
Jun 30, 2024 67,000.00
Mar 31, 2024 71,000.00
Dec 31, 2023 107,000.00
Sep 30, 2023 12,000.00
Jun 30, 2023 127,000.00
Mar 31, 2023 54,000.00
Dec 31, 2022 73,000.00
Sep 30, 2022 45,000.00
Jun 30, 2022 121,000.00
Mar 31, 2022 130,000.00
Dec 31, 2021 -121,000.00
Sep 30, 2021 106,000.00
Jun 30, 2021 134,000.00
Mar 31, 2021 149,000.00