Karyopharm Therapeutics (KPTI) Non Operating Income (2013 - 2025)
Karyopharm Therapeutics (KPTI) reported Non Operating Income of $21.7 million for Q4 2025, up 5437.76% on a YoY basis from $392000.0 in Q4 2024, and up 221.46% quarter-over-quarter from -$17.9 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Non Operating Income (2013 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Non Operating Income for 13 years, with the latest figure at $21.7 million in Q4 2025.
- For the quarter ending Q4 2025, Non Operating Income rose 5437.76% year-over-year to $21.7 million; the trailing twelve-month figure through Dec 2025 stood at $10.8 million (down 76.85% YoY), and the FY2025 full-year result was $840000.0, down 98.05% from the prior year.
- Non Operating Income for Q4 2025 stood at $21.7 million, up from -$17.9 million in the prior quarter.
- The five-year high for Non Operating Income was $52.0 million in Q2 2024, with the low at -$25.9 million in Q4 2021.
- Historically, Non Operating Income has averaged $598900.0 across 5 years, with a median of -$142000.0 in 2022.
- Annual changes were most pronounced in 2022 — Non Operating Income plunged 30322.22% — and 2024, when it surged 173163.33%.
- Karyopharm Therapeutics' Non Operating Income stood at -$25.9 million in 2021, then jumped by 82.41% to -$4.6 million in 2022, then jumped by 95.38% to -$211000.0 in 2023, then surged by 285.78% to $392000.0 in 2024, then jumped by 5437.76% to $21.7 million in 2025.
- The last three Non Operating Income figures came in at $21.7 million (Q4 2025), -$17.9 million (Q3 2025), and -$12.8 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Non Op. Inc. (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | 5.75 Mn |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | - |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | 444,000.00 |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | - |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | 9.35 Mn |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn | 21.71 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 21.71 Mn |
| Sep 30, 2025 | -17.87 Mn |
| Jun 30, 2025 | -12.83 Mn |
| Mar 31, 2025 | 19.82 Mn |
| Dec 31, 2024 | 392,000.00 |
| Sep 30, 2024 | -5.76 Mn |
| Jun 30, 2024 | 51.98 Mn |
| Mar 31, 2024 | 196,000.00 |
| Dec 31, 2023 | -211,000.00 |
| Sep 30, 2023 | 89,000.00 |
| Jun 30, 2023 | 30,000.00 |
| Mar 31, 2023 | -264,000.00 |
| Dec 31, 2022 | -4.56 Mn |
| Sep 30, 2022 | -5.44 Mn |
| Jun 30, 2022 | -13,000.00 |
| Mar 31, 2022 | -73,000.00 |
| Dec 31, 2021 | -25.94 Mn |
| Sep 30, 2021 | 18,000.00 |
| Jun 30, 2021 | -4.40 Mn |
| Mar 31, 2021 | -4.89 Mn |