Karyopharm Therapeutics (KPTI) Non Operating Income (2013 - 2025)

Karyopharm Therapeutics (KPTI) reported Non Operating Income of $21.7 million for Q4 2025, up 5437.76% on a YoY basis from $392000.0 in Q4 2024, and up 221.46% quarter-over-quarter from -$17.9 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Non Operating Income (2013 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Non Operating Income for 13 years, with the latest figure at $21.7 million in Q4 2025.

  • For the quarter ending Q4 2025, Non Operating Income rose 5437.76% year-over-year to $21.7 million; the trailing twelve-month figure through Dec 2025 stood at $10.8 million (down 76.85% YoY), and the FY2025 full-year result was $840000.0, down 98.05% from the prior year.
  • Non Operating Income for Q4 2025 stood at $21.7 million, up from -$17.9 million in the prior quarter.
  • The five-year high for Non Operating Income was $52.0 million in Q2 2024, with the low at -$25.9 million in Q4 2021.
  • Historically, Non Operating Income has averaged $598900.0 across 5 years, with a median of -$142000.0 in 2022.
  • Annual changes were most pronounced in 2022 — Non Operating Income plunged 30322.22% — and 2024, when it surged 173163.33%.
  • Karyopharm Therapeutics' Non Operating Income stood at -$25.9 million in 2021, then jumped by 82.41% to -$4.6 million in 2022, then jumped by 95.38% to -$211000.0 in 2023, then surged by 285.78% to $392000.0 in 2024, then jumped by 5437.76% to $21.7 million in 2025.
  • The last three Non Operating Income figures came in at $21.7 million (Q4 2025), -$17.9 million (Q3 2025), and -$12.8 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Non Op. Inc. (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - 5.75 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 444,000.00
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn -
9 Abivax 91.71 Bn 91.71 Bn - 9.35 Mn
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 21.71 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 21.71 Mn
Sep 30, 2025 -17.87 Mn
Jun 30, 2025 -12.83 Mn
Mar 31, 2025 19.82 Mn
Dec 31, 2024 392,000.00
Sep 30, 2024 -5.76 Mn
Jun 30, 2024 51.98 Mn
Mar 31, 2024 196,000.00
Dec 31, 2023 -211,000.00
Sep 30, 2023 89,000.00
Jun 30, 2023 30,000.00
Mar 31, 2023 -264,000.00
Dec 31, 2022 -4.56 Mn
Sep 30, 2022 -5.44 Mn
Jun 30, 2022 -13,000.00
Mar 31, 2022 -73,000.00
Dec 31, 2021 -25.94 Mn
Sep 30, 2021 18,000.00
Jun 30, 2021 -4.40 Mn
Mar 31, 2021 -4.89 Mn