Karyopharm Therapeutics (KPTI) Cash from Operations (2012 - 2025)
Karyopharm Therapeutics (KPTI) recorded Cash from Operations of -$11.83 million in Q4 2025, compared with -$25.81 million a year earlier.
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Analysis
Karyopharm Therapeutics (KPTI) Cash from Operations (2012 - 2025) Analysis & Trends
For FY2025, Karyopharm Therapeutics reported Cash from Operations of -$75.37 million.
- Across earlier years, Cash from Operations came in at -$127.49 million in FY2024, -$92.72 million in FY2023, -$149.55 million in FY2022 and -$107.12 million in FY2021.
- Quarterly Cash from Operations has ranged from -$59.2 million in Q1 2022 to $25.48 million in Q4 2021 over the past five years.
- Per Business Quant, the preceding three quarters came in at -$5.86 million (Q3 2025), -$18.7 million (Q2 2025) and -$38.98 million (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Ops. (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,148.60 Bn | 1,117.19 Bn | 19.71 Bn | 10.69 Bn |
| 2 | Johnson & Johnson | 637.24 Bn | 557.10 Bn | 17.30 Bn | 7.72 Bn |
| 3 | AbbVie | 502.40 Bn | 475.51 Bn | 12.70 Bn | 3.44 Bn |
| 4 | Merck | 356.72 Bn | 311.10 Bn | 12.21 Bn | 5.37 Bn |
| 5 | Novartis Ag | 301.65 Bn | 265.64 Bn | 11.24 Bn | 5.88 Bn |
| 6 | Astrazeneca | 265.03 Bn | 238.72 Bn | 12.86 Bn | 2.87 Bn |
| 7 | Amgen | 239.14 Bn | 194.54 Bn | 7.24 Bn | 4.00 Bn |
| 8 | Gilead Sciences | 194.82 Bn | 169.02 Bn | 6.22 Bn | 3.57 Bn |
| 9 | Pfizer | 172.31 Bn | 118.96 Bn | 10.94 Bn | 835.00 Mn |
| 10 | Karyopharm Therapeutics | 15.35 Mn | -211.07 Mn | 32.35 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -11.83 Mn |
| Sep 30, 2025 | -5.86 Mn |
| Jun 30, 2025 | -18.70 Mn |
| Mar 31, 2025 | -38.98 Mn |
| Dec 31, 2024 | -25.81 Mn |
| Sep 30, 2024 | -19.45 Mn |
| Jun 30, 2024 | -38.50 Mn |
| Mar 31, 2024 | -43.73 Mn |
| Dec 31, 2023 | -18.59 Mn |
| Sep 30, 2023 | -29.53 Mn |
| Jun 30, 2023 | -25.70 Mn |
| Mar 31, 2023 | -18.91 Mn |
| Dec 31, 2022 | -26.84 Mn |
| Sep 30, 2022 | -28.37 Mn |
| Jun 30, 2022 | -35.14 Mn |
| Mar 31, 2022 | -59.20 Mn |
| Dec 31, 2021 | 25.48 Mn |
| Sep 30, 2021 | -23.96 Mn |
| Jun 30, 2021 | -55.75 Mn |
| Mar 31, 2021 | -52.89 Mn |
API Access
Karyopharm Therapeutics Cash from Operations API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=cash-from-operations&ticker=KPTI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "cash-from-operations", "ticker": "KPTI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=cash-from-operations&ticker=KPTI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();