Karyopharm Therapeutics (KPTI) Total Liabilities (2012 - 2025)
Karyopharm Therapeutics (KPTI) reported Total Liabilities of $401.3 million for Q4 2025, up 14.53% on a YoY basis from $350.4 million in Q4 2024, and up 9.81% quarter-over-quarter from $365.5 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Total Liabilities (2012 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Total Liabilities for 14 years, with the latest figure at $401.3 million in Q4 2025.
- For the quarter ending Q4 2025, Total Liabilities rose 14.53% year-over-year to $401.3 million; the trailing twelve-month figure through Dec 2025 stood at $401.3 million (up 14.53% YoY), and the FY2025 full-year result was $401.3 million, up 14.53% from the prior year.
- Total Liabilities for Q4 2025 stood at $401.3 million, up from $365.5 million in the prior quarter.
- The five-year high for Total Liabilities was $401.3 million in Q4 2025, with the low at $314.5 million in Q1 2021.
- Historically, Total Liabilities has averaged $364.8 million across 5 years, with a median of $370.7 million in 2023.
- Annual changes were most pronounced in 2021 — Total Liabilities soared 49.74% — and 2025, when it fell 10.66%.
- Karyopharm Therapeutics' Total Liabilities stood at $385.0 million in 2021, then slipped by 2.64% to $374.8 million in 2022, then climbed by 0.48% to $376.6 million in 2023, then declined by 6.96% to $350.4 million in 2024, then increased by 14.53% to $401.3 million in 2025.
- The last three Total Liabilities figures came in at $401.3 million (Q4 2025), $365.5 million (Q3 2025), and $343.8 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Total Liabilities (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | 1.74 Mn |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | 15.48 Mn |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | 16.35 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | 731.60 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | 19.51 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | 10.44 Mn |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | 943,068.00 |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 7.12 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | 137.56 Mn |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn | 401.34 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 401.34 Mn |
| Sep 30, 2025 | 365.49 Mn |
| Jun 30, 2025 | 343.81 Mn |
| Mar 31, 2025 | 333.60 Mn |
| Dec 31, 2024 | 350.44 Mn |
| Sep 30, 2024 | 349.12 Mn |
| Jun 30, 2024 | 346.12 Mn |
| Mar 31, 2024 | 373.41 Mn |
| Dec 31, 2023 | 376.64 Mn |
| Sep 30, 2023 | 370.36 Mn |
| Jun 30, 2023 | 369.08 Mn |
| Mar 31, 2023 | 370.97 Mn |
| Dec 31, 2022 | 374.83 Mn |
| Sep 30, 2022 | 371.52 Mn |
| Jun 30, 2022 | 372.82 Mn |
| Mar 31, 2022 | 377.11 Mn |
| Dec 31, 2021 | 384.98 Mn |
| Sep 30, 2021 | 380.07 Mn |
| Jun 30, 2021 | 369.70 Mn |
| Mar 31, 2021 | 314.55 Mn |