Karyopharm Therapeutics (KPTI) Total Liabilities (2012 - 2025)

Karyopharm Therapeutics (KPTI) reported Total Liabilities of $401.3 million for Q4 2025, up 14.53% on a YoY basis from $350.4 million in Q4 2024, and up 9.81% quarter-over-quarter from $365.5 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Total Liabilities (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Total Liabilities for 14 years, with the latest figure at $401.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Total Liabilities rose 14.53% year-over-year to $401.3 million; the trailing twelve-month figure through Dec 2025 stood at $401.3 million (up 14.53% YoY), and the FY2025 full-year result was $401.3 million, up 14.53% from the prior year.
  • Total Liabilities for Q4 2025 stood at $401.3 million, up from $365.5 million in the prior quarter.
  • The five-year high for Total Liabilities was $401.3 million in Q4 2025, with the low at $314.5 million in Q1 2021.
  • Historically, Total Liabilities has averaged $364.8 million across 5 years, with a median of $370.7 million in 2023.
  • Annual changes were most pronounced in 2021 — Total Liabilities soared 49.74% — and 2025, when it fell 10.66%.
  • Karyopharm Therapeutics' Total Liabilities stood at $385.0 million in 2021, then slipped by 2.64% to $374.8 million in 2022, then climbed by 0.48% to $376.6 million in 2023, then declined by 6.96% to $350.4 million in 2024, then increased by 14.53% to $401.3 million in 2025.
  • The last three Total Liabilities figures came in at $401.3 million (Q4 2025), $365.5 million (Q3 2025), and $343.8 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Total Liabilities (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 1.74 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - 15.48 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 16.35 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 731.60 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 19.51 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - 10.44 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 943,068.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 7.12 Bn
9 Abivax 91.71 Bn 91.71 Bn - 137.56 Mn
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 401.34 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 401.34 Mn
Sep 30, 2025 365.49 Mn
Jun 30, 2025 343.81 Mn
Mar 31, 2025 333.60 Mn
Dec 31, 2024 350.44 Mn
Sep 30, 2024 349.12 Mn
Jun 30, 2024 346.12 Mn
Mar 31, 2024 373.41 Mn
Dec 31, 2023 376.64 Mn
Sep 30, 2023 370.36 Mn
Jun 30, 2023 369.08 Mn
Mar 31, 2023 370.97 Mn
Dec 31, 2022 374.83 Mn
Sep 30, 2022 371.52 Mn
Jun 30, 2022 372.82 Mn
Mar 31, 2022 377.11 Mn
Dec 31, 2021 384.98 Mn
Sep 30, 2021 380.07 Mn
Jun 30, 2021 369.70 Mn
Mar 31, 2021 314.55 Mn