Karyopharm Therapeutics (KPTI) Cost of Revenue (2019 - 2025)
Karyopharm Therapeutics (KPTI) reported Cost of Revenue of $1.3 million for Q4 2025, up 0.83% on a YoY basis from $1.3 million in Q4 2024, and down 35.54% quarter-over-quarter from $2.1 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Cost of Revenue (2019 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Cost of Revenue for 6 years, with the latest figure at $1.3 million in Q4 2025.
- For the quarter ending Q4 2025, Cost of Revenue rose 0.83% year-over-year to $1.3 million; the trailing twelve-month figure through Dec 2025 stood at $5.7 million (down 4.22% YoY), and the FY2025 full-year result was $5.8 million, down 3.33% from the prior year.
- Cost of Revenue for Q4 2025 stood at $1.3 million, down from $2.1 million in the prior quarter.
- The five-year high for Cost of Revenue was $2.1 million in Q3 2025, with the low at $589000.0 in Q3 2021.
- Historically, Cost of Revenue has averaged $1.3 million across 5 years, with a median of $1.3 million in 2024.
- Annual changes were most pronounced in 2022 — Cost of Revenue jumped 151.75% — and 2025, when it sank 34.33%.
- Karyopharm Therapeutics' Cost of Revenue stood at $742000.0 in 2021, then jumped by 151.75% to $1.9 million in 2022, then retreated by 20.45% to $1.5 million in 2023, then fell by 10.43% to $1.3 million in 2024, then advanced by 0.83% to $1.3 million in 2025.
- The last three Cost of Revenue figures came in at $1.3 million (Q4 2025), $2.1 million (Q3 2025), and $1.0 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cost of Rev (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | 64.20 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | - |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | 48,670.00 |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 392.80 Mn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | 2.05 Mn |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn | 1.34 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 1.34 Mn |
| Dec 31, 2025 | 1.34 Mn |
| Sep 30, 2025 | 2.08 Mn |
| Sep 30, 2025 | 2.08 Mn |
| Jun 30, 2025 | 1.02 Mn |
| Jun 30, 2025 | 1.02 Mn |
| Mar 31, 2025 | 1.26 Mn |
| Mar 31, 2025 | 1.26 Mn |
| Dec 31, 2024 | 1.33 Mn |
| Dec 31, 2024 | 1.33 Mn |
| Sep 30, 2024 | 1.30 Mn |
| Sep 30, 2024 | 1.30 Mn |
| Jun 30, 2024 | 1.40 Mn |
| Jun 30, 2024 | 1.40 Mn |
| Mar 31, 2024 | 1.91 Mn |
| Mar 31, 2024 | 1.91 Mn |
| Dec 31, 2023 | 1.49 Mn |
| Dec 31, 2023 | 1.49 Mn |
| Sep 30, 2023 | 911,000.00 |
| Sep 30, 2023 | 911,000.00 |