Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.96 +0.14 (+7.69%)
At close: Aug 21, 2026 · 4:00 PM EDT

Karyopharm Therapeutics (KPTI) Cost of Revenue (2019 - 2026)

Karyopharm Therapeutics' (KPTI) quarterly Cost of Revenue came in at $1.5 million in Q4 2025, up 13.58% YoY from $1.3 million in Q4 2024, and down 31.14% on a QoQ basis from $2.1 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Cost of Revenue (2019 - 2026) Analysis & Trends

Karyopharm Therapeutics (KPTI) has 6 years of Cost of Revenue data on file, last reported at $1.5 million in Q4 2025.

  • Quarterly Cost of Revenue rose 13.58% year-over-year to $1.5 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $5.9 million (up 0.86% YoY) and the FY2025 annual result came in at $5.8 million, changed 0.47% from the prior year.
  • Cost of Revenue declined to $1.5 million in Q4 2025, from $2.1 million in the prior quarter.
  • In the past five years, Cost of Revenue ranged from a high of $2.1 million in Q3 2025 to a low of $589000.0 in Q3 2021.
  • A 5-year average of $1.2 million and a median of $1.2 million in 2024 frame the typical range for Cost of Revenue.
  • Annual changes were most pronounced in 2022 — Cost of Revenue jumped 121.29% — and 2023, when it sank 32.03%.
  • Tracing KPTI's Cost of Revenue over 5 years: stood at $742000.0 in 2021, then jumped by 121.29% to $1.6 million in 2022, then slumped by 32.03% to $1.1 million in 2023, then gained by 14.78% to $1.3 million in 2024, then rose by 13.58% to $1.5 million in 2025.
  • The last three Cost of Revenue figures came in at $1.5 million (Q4 2025), $2.1 million (Q3 2025), and $1.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cost of Rev (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 489.20 Mn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 360.70 Mn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 145.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn 93.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 174.53 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 298.26 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 387.98 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn 67.21 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - -
10 Karyopharm Therapeutics 56.72 Mn 56.72 Mn 32.35 Mn 1.09 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 1.09 Mn
Jun 30, 2026 1.09 Mn
Dec 31, 2025 1.46 Mn
Dec 31, 2025 1.46 Mn
Sep 30, 2025 2.11 Mn
Sep 30, 2025 2.11 Mn
Jun 30, 2025 1.02 Mn
Jun 30, 2025 1.02 Mn
Mar 31, 2025 1.30 Mn
Mar 31, 2025 1.30 Mn
Dec 31, 2024 1.28 Mn
Dec 31, 2024 1.28 Mn
Sep 30, 2024 1.24 Mn
Sep 30, 2024 1.24 Mn
Jun 30, 2024 1.40 Mn
Jun 30, 2024 1.40 Mn
Mar 31, 2024 1.91 Mn
Mar 31, 2024 1.91 Mn
Dec 31, 2023 1.12 Mn
Dec 31, 2023 1.12 Mn