Karyopharm Therapeutics (KPTI) Cost of Revenue (2019 - 2025)

Karyopharm Therapeutics (KPTI) reported Cost of Revenue of $1.3 million for Q4 2025, up 0.83% on a YoY basis from $1.3 million in Q4 2024, and down 35.54% quarter-over-quarter from $2.1 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Cost of Revenue (2019 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Cost of Revenue for 6 years, with the latest figure at $1.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Cost of Revenue rose 0.83% year-over-year to $1.3 million; the trailing twelve-month figure through Dec 2025 stood at $5.7 million (down 4.22% YoY), and the FY2025 full-year result was $5.8 million, down 3.33% from the prior year.
  • Cost of Revenue for Q4 2025 stood at $1.3 million, down from $2.1 million in the prior quarter.
  • The five-year high for Cost of Revenue was $2.1 million in Q3 2025, with the low at $589000.0 in Q3 2021.
  • Historically, Cost of Revenue has averaged $1.3 million across 5 years, with a median of $1.3 million in 2024.
  • Annual changes were most pronounced in 2022 — Cost of Revenue jumped 151.75% — and 2025, when it sank 34.33%.
  • Karyopharm Therapeutics' Cost of Revenue stood at $742000.0 in 2021, then jumped by 151.75% to $1.9 million in 2022, then retreated by 20.45% to $1.5 million in 2023, then fell by 10.43% to $1.3 million in 2024, then advanced by 0.83% to $1.3 million in 2025.
  • The last three Cost of Revenue figures came in at $1.3 million (Q4 2025), $2.1 million (Q3 2025), and $1.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cost of Rev (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 64.20 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 48,670.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 392.80 Mn
9 Abivax 91.71 Bn 91.71 Bn - 2.05 Mn
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 1.34 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 1.34 Mn
Dec 31, 2025 1.34 Mn
Sep 30, 2025 2.08 Mn
Sep 30, 2025 2.08 Mn
Jun 30, 2025 1.02 Mn
Jun 30, 2025 1.02 Mn
Mar 31, 2025 1.26 Mn
Mar 31, 2025 1.26 Mn
Dec 31, 2024 1.33 Mn
Dec 31, 2024 1.33 Mn
Sep 30, 2024 1.30 Mn
Sep 30, 2024 1.30 Mn
Jun 30, 2024 1.40 Mn
Jun 30, 2024 1.40 Mn
Mar 31, 2024 1.91 Mn
Mar 31, 2024 1.91 Mn
Dec 31, 2023 1.49 Mn
Dec 31, 2023 1.49 Mn
Sep 30, 2023 911,000.00
Sep 30, 2023 911,000.00