Karyopharm Therapeutics (KPTI) Cost of Revenue (2019 - 2026)
Karyopharm Therapeutics' (KPTI) quarterly Cost of Revenue came in at $1.5 million in Q4 2025, up 13.58% YoY from $1.3 million in Q4 2024, and down 31.14% on a QoQ basis from $2.1 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Cost of Revenue (2019 - 2026) Analysis & Trends
Karyopharm Therapeutics (KPTI) has 6 years of Cost of Revenue data on file, last reported at $1.5 million in Q4 2025.
- Quarterly Cost of Revenue rose 13.58% year-over-year to $1.5 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $5.9 million (up 0.86% YoY) and the FY2025 annual result came in at $5.8 million, changed 0.47% from the prior year.
- Cost of Revenue declined to $1.5 million in Q4 2025, from $2.1 million in the prior quarter.
- In the past five years, Cost of Revenue ranged from a high of $2.1 million in Q3 2025 to a low of $589000.0 in Q3 2021.
- A 5-year average of $1.2 million and a median of $1.2 million in 2024 frame the typical range for Cost of Revenue.
- Annual changes were most pronounced in 2022 — Cost of Revenue jumped 121.29% — and 2023, when it sank 32.03%.
- Tracing KPTI's Cost of Revenue over 5 years: stood at $742000.0 in 2021, then jumped by 121.29% to $1.6 million in 2022, then slumped by 32.03% to $1.1 million in 2023, then gained by 14.78% to $1.3 million in 2024, then rose by 13.58% to $1.5 million in 2025.
- The last three Cost of Revenue figures came in at $1.5 million (Q4 2025), $2.1 million (Q3 2025), and $1.0 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cost of Rev (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.13 Bn | 131.28 Bn | 2.84 Bn | 489.20 Mn |
| 2 | Regeneron Pharmaceuticals | 85.77 Bn | 77.77 Bn | 3.93 Bn | 360.70 Mn |
| 3 | Argenx Se | 64.64 Bn | 59.46 Bn | 1.37 Bn | 145.00 Mn |
| 4 | Moderna | 58.29 Bn | 53.16 Bn | 52.00 Mn | 93.00 Mn |
| 5 | BeOne Medicines | 41.92 Bn | 36.82 Bn | 1.53 Bn | 174.53 Mn |
| 6 | Alnylam Pharmaceuticals | 31.58 Bn | 28.28 Bn | 992.69 Mn | 298.26 Mn |
| 7 | BioNTech SE | 28.12 Bn | 9.73 Bn | 668.28 Mn | 387.98 Mn |
| 8 | Insmed | 27.39 Bn | 26.22 Bn | 358.27 Mn | 67.21 Mn |
| 9 | Royalty Pharma | 27.27 Bn | 26.43 Bn | - | - |
| 10 | Karyopharm Therapeutics | 56.72 Mn | 56.72 Mn | 32.35 Mn | 1.09 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 1.09 Mn |
| Jun 30, 2026 | 1.09 Mn |
| Dec 31, 2025 | 1.46 Mn |
| Dec 31, 2025 | 1.46 Mn |
| Sep 30, 2025 | 2.11 Mn |
| Sep 30, 2025 | 2.11 Mn |
| Jun 30, 2025 | 1.02 Mn |
| Jun 30, 2025 | 1.02 Mn |
| Mar 31, 2025 | 1.30 Mn |
| Mar 31, 2025 | 1.30 Mn |
| Dec 31, 2024 | 1.28 Mn |
| Dec 31, 2024 | 1.28 Mn |
| Sep 30, 2024 | 1.24 Mn |
| Sep 30, 2024 | 1.24 Mn |
| Jun 30, 2024 | 1.40 Mn |
| Jun 30, 2024 | 1.40 Mn |
| Mar 31, 2024 | 1.91 Mn |
| Mar 31, 2024 | 1.91 Mn |
| Dec 31, 2023 | 1.12 Mn |
| Dec 31, 2023 | 1.12 Mn |