Karyopharm Therapeutics (KPTI) Interest Expenses (2015 - 2025)

Karyopharm Therapeutics (KPTI) reported Interest Expenses of $12.6 million for Q4 2025, up 12.63% on a YoY basis from $11.2 million in Q4 2024, and up 14.63% quarter-over-quarter from $11.0 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Interest Expenses (2015 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Interest Expenses for 8 years, with the latest figure at $12.6 million in Q4 2025.

  • For the quarter ending Q4 2025, Interest Expenses rose 12.63% year-over-year to $12.6 million; the trailing twelve-month figure through Dec 2025 stood at $45.8 million (up 22.52% YoY), and the FY2025 full-year result was $45.8 million, up 22.52% from the prior year.
  • Interest Expenses for Q4 2025 stood at $12.6 million, up from $11.0 million in the prior quarter.
  • The five-year high for Interest Expenses was $12.6 million in Q4 2025, with the low at $5.0 million in Q2 2021.
  • Historically, Interest Expenses has averaged $7.9 million across 5 years, with a median of $6.5 million in 2022.
  • Annual changes were most pronounced in 2021 — Interest Expenses retreated 26.0% — and 2024, when it surged 87.47%.
  • Karyopharm Therapeutics' Interest Expenses stood at $7.9 million in 2021, then decreased by 25.88% to $5.9 million in 2022, then advanced by 5.49% to $6.2 million in 2023, then jumped by 80.48% to $11.2 million in 2024, then climbed by 12.63% to $12.6 million in 2025.
  • The last three Interest Expenses figures came in at $12.6 million (Q4 2025), $11.0 million (Q3 2025), and $11.2 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Interest Expense (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -5.50 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 61,000.00
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -332,000.00
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -2,753.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn -
9 Abivax 91.71 Bn 91.71 Bn - -5.58 Mn
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 12.62 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 12.62 Mn
Dec 31, 2025 12.62 Mn
Sep 30, 2025 11.01 Mn
Sep 30, 2025 11.01 Mn
Jun 30, 2025 11.23 Mn
Jun 30, 2025 11.23 Mn
Mar 31, 2025 10.99 Mn
Mar 31, 2025 10.99 Mn
Dec 31, 2024 11.20 Mn
Dec 31, 2024 11.20 Mn
Sep 30, 2024 11.39 Mn
Sep 30, 2024 11.39 Mn
Jun 30, 2024 8.95 Mn
Jun 30, 2024 8.95 Mn
Mar 31, 2024 5.88 Mn
Mar 31, 2024 5.88 Mn
Dec 31, 2023 6.21 Mn
Dec 31, 2023 6.21 Mn
Sep 30, 2023 6.07 Mn
Sep 30, 2023 6.07 Mn