Karyopharm Therapeutics (KPTI) Interest Expenses (2015 - 2025)
Karyopharm Therapeutics (KPTI) reported Interest Expenses of $12.6 million for Q4 2025, up 12.63% on a YoY basis from $11.2 million in Q4 2024, and up 14.63% quarter-over-quarter from $11.0 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Interest Expenses (2015 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Interest Expenses for 8 years, with the latest figure at $12.6 million in Q4 2025.
- For the quarter ending Q4 2025, Interest Expenses rose 12.63% year-over-year to $12.6 million; the trailing twelve-month figure through Dec 2025 stood at $45.8 million (up 22.52% YoY), and the FY2025 full-year result was $45.8 million, up 22.52% from the prior year.
- Interest Expenses for Q4 2025 stood at $12.6 million, up from $11.0 million in the prior quarter.
- The five-year high for Interest Expenses was $12.6 million in Q4 2025, with the low at $5.0 million in Q2 2021.
- Historically, Interest Expenses has averaged $7.9 million across 5 years, with a median of $6.5 million in 2022.
- Annual changes were most pronounced in 2021 — Interest Expenses retreated 26.0% — and 2024, when it surged 87.47%.
- Karyopharm Therapeutics' Interest Expenses stood at $7.9 million in 2021, then decreased by 25.88% to $5.9 million in 2022, then advanced by 5.49% to $6.2 million in 2023, then jumped by 80.48% to $11.2 million in 2024, then climbed by 12.63% to $12.6 million in 2025.
- The last three Interest Expenses figures came in at $12.6 million (Q4 2025), $11.0 million (Q3 2025), and $11.2 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Interest Expense (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | -5.50 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | 61,000.00 |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | -332,000.00 |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | -2,753.00 |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | - |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | -5.58 Mn |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn | 12.62 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 12.62 Mn |
| Dec 31, 2025 | 12.62 Mn |
| Sep 30, 2025 | 11.01 Mn |
| Sep 30, 2025 | 11.01 Mn |
| Jun 30, 2025 | 11.23 Mn |
| Jun 30, 2025 | 11.23 Mn |
| Mar 31, 2025 | 10.99 Mn |
| Mar 31, 2025 | 10.99 Mn |
| Dec 31, 2024 | 11.20 Mn |
| Dec 31, 2024 | 11.20 Mn |
| Sep 30, 2024 | 11.39 Mn |
| Sep 30, 2024 | 11.39 Mn |
| Jun 30, 2024 | 8.95 Mn |
| Jun 30, 2024 | 8.95 Mn |
| Mar 31, 2024 | 5.88 Mn |
| Mar 31, 2024 | 5.88 Mn |
| Dec 31, 2023 | 6.21 Mn |
| Dec 31, 2023 | 6.21 Mn |
| Sep 30, 2023 | 6.07 Mn |
| Sep 30, 2023 | 6.07 Mn |