Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.96 +0.14 (+7.69%)
At close: Aug 21, 2026 · 4:00 PM EDT

Karyopharm Therapeutics (KPTI) Change in Account Payables (2012 - 2025)

Karyopharm Therapeutics' (KPTI) quarterly Change in Account Payables came in at -$1.4 million in Q4 2025, down 105.47% YoY from $25.4 million in Q4 2024, and down 149.7% on a QoQ basis from $2.8 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Change in Account Payables (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics (KPTI) has 14 years of Change in Account Payables data on file, last reported at -$1.4 million in Q4 2025.

  • Quarterly Change in Account Payables fell 105.47% year-over-year to -$1.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$1.1 million (down 155.65% YoY) and the FY2025 annual result came in at -$1.1 million, down 155.65% from the prior year.
  • Change in Account Payables declined to -$1.4 million in Q4 2025, from $2.8 million in the prior quarter.
  • In the past five years, Change in Account Payables ranged from a high of $6.3 million in Q1 2023 to a low of -$6.8 million in Q2 2023.
  • A 5-year average of -$22350.0 and a median of -$703500.0 in 2021 frame the typical range for Change in Account Payables.
  • Annual changes were most pronounced in 2021 — Change in Account Payables plunged 480.73% — and 2024, when it soared 322.17%.
  • Tracing KPTI's Change in Account Payables over 5 years: stood at $722000.0 in 2021, then jumped by 171.47% to $2.0 million in 2022, then increased by 11.22% to $2.2 million in 2023, then sank by 131.01% to -$676000.0 in 2024, then tumbled by 105.47% to -$1.4 million in 2025.
  • The last three Change in Account Payables figures came in at -$1.4 million (Q4 2025), $2.8 million (Q3 2025), and -$3.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Account Payables (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn -66.70 Mn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn -
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -8.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 37.53 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn -
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -
9 Royalty Pharma 27.27 Bn 26.43 Bn - -
10 Karyopharm Therapeutics 56.72 Mn 56.72 Mn 32.35 Mn -

Historic Data

Download Data
DateValue
Dec 31, 2025 -1.39 Mn
Dec 31, 2025 -1.39 Mn
Sep 30, 2025 2.80 Mn
Sep 30, 2025 2.80 Mn
Jun 30, 2025 -3.28 Mn
Jun 30, 2025 -3.28 Mn
Mar 31, 2025 765,000.00
Mar 31, 2025 765,000.00
Dec 31, 2024 -676,000.00
Dec 31, 2024 -676,000.00
Sep 30, 2024 2.99 Mn
Sep 30, 2024 2.99 Mn
Jun 30, 2024 -2.23 Mn
Jun 30, 2024 -2.23 Mn
Mar 31, 2024 1.91 Mn
Mar 31, 2024 1.91 Mn
Dec 31, 2023 2.18 Mn
Dec 31, 2023 2.18 Mn
Sep 30, 2023 -1.34 Mn
Sep 30, 2023 -1.34 Mn