Karyopharm Therapeutics (KPTI) Change in Account Payables (2012 - 2025)

Karyopharm Therapeutics (KPTI) reported Change in Account Payables of -$1.4 million for Q4 2025, down 105.47% on a YoY basis from $25.4 million in Q4 2024, and down 149.7% quarter-over-quarter from $2.8 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Change in Account Payables (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Change in Account Payables for 14 years, with the latest figure at -$1.4 million in Q4 2025.

  • For the quarter ending Q4 2025, Change in Account Payables fell 105.47% year-over-year to -$1.4 million; the trailing twelve-month figure through Dec 2025 stood at -$1.1 million (down 155.65% YoY), and the FY2025 full-year result was -$1.1 million, down 155.65% from the prior year.
  • Change in Account Payables for Q4 2025 stood at -$1.4 million, down from $2.8 million in the prior quarter.
  • The five-year high for Change in Account Payables was $6.3 million in Q1 2023, with the low at -$6.8 million in Q2 2023.
  • Historically, Change in Account Payables has averaged -$22350.0 across 5 years, with a median of -$703500.0 in 2021.
  • Annual changes were most pronounced in 2021 — Change in Account Payables plunged 480.73% — and 2024, when it soared 322.17%.
  • Karyopharm Therapeutics' Change in Account Payables stood at $722000.0 in 2021, then jumped by 171.47% to $2.0 million in 2022, then increased by 11.22% to $2.2 million in 2023, then sank by 131.01% to -$676000.0 in 2024, then tumbled by 105.47% to -$1.4 million in 2025.
  • The last three Change in Account Payables figures came in at -$1.4 million (Q4 2025), $2.8 million (Q3 2025), and -$3.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Account Payables (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -3.26 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 35.60 Mn
9 Abivax 91.71 Bn 91.71 Bn - -9.42 Mn
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn -1.39 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -1.39 Mn
Dec 31, 2025 -1.39 Mn
Sep 30, 2025 2.80 Mn
Sep 30, 2025 2.80 Mn
Jun 30, 2025 -3.28 Mn
Jun 30, 2025 -3.28 Mn
Mar 31, 2025 765,000.00
Mar 31, 2025 765,000.00
Dec 31, 2024 -676,000.00
Dec 31, 2024 -676,000.00
Sep 30, 2024 2.99 Mn
Sep 30, 2024 2.99 Mn
Jun 30, 2024 -2.23 Mn
Jun 30, 2024 -2.23 Mn
Mar 31, 2024 1.91 Mn
Mar 31, 2024 1.91 Mn
Dec 31, 2023 2.18 Mn
Dec 31, 2023 2.18 Mn
Sep 30, 2023 -1.34 Mn
Sep 30, 2023 -1.34 Mn