Karyopharm Therapeutics (KPTI) Change in Account Payables (2012 - 2025)
Karyopharm Therapeutics' (KPTI) quarterly Change in Account Payables came in at -$1.4 million in Q4 2025, down 105.47% YoY from $25.4 million in Q4 2024, and down 149.7% on a QoQ basis from $2.8 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Change in Account Payables (2012 - 2025) Analysis & Trends
Karyopharm Therapeutics (KPTI) has 14 years of Change in Account Payables data on file, last reported at -$1.4 million in Q4 2025.
- Quarterly Change in Account Payables fell 105.47% year-over-year to -$1.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$1.1 million (down 155.65% YoY) and the FY2025 annual result came in at -$1.1 million, down 155.65% from the prior year.
- Change in Account Payables declined to -$1.4 million in Q4 2025, from $2.8 million in the prior quarter.
- In the past five years, Change in Account Payables ranged from a high of $6.3 million in Q1 2023 to a low of -$6.8 million in Q2 2023.
- A 5-year average of -$22350.0 and a median of -$703500.0 in 2021 frame the typical range for Change in Account Payables.
- Annual changes were most pronounced in 2021 — Change in Account Payables plunged 480.73% — and 2024, when it soared 322.17%.
- Tracing KPTI's Change in Account Payables over 5 years: stood at $722000.0 in 2021, then jumped by 171.47% to $2.0 million in 2022, then increased by 11.22% to $2.2 million in 2023, then sank by 131.01% to -$676000.0 in 2024, then tumbled by 105.47% to -$1.4 million in 2025.
- The last three Change in Account Payables figures came in at -$1.4 million (Q4 2025), $2.8 million (Q3 2025), and -$3.3 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Account Payables (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.13 Bn | 131.28 Bn | 2.84 Bn | -66.70 Mn |
| 2 | Regeneron Pharmaceuticals | 85.77 Bn | 77.77 Bn | 3.93 Bn | - |
| 3 | Argenx Se | 64.64 Bn | 59.46 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.29 Bn | 53.16 Bn | 52.00 Mn | -8.00 Mn |
| 5 | BeOne Medicines | 41.92 Bn | 36.82 Bn | 1.53 Bn | 37.53 Mn |
| 6 | Alnylam Pharmaceuticals | 31.58 Bn | 28.28 Bn | 992.69 Mn | - |
| 7 | BioNTech SE | 28.12 Bn | 9.73 Bn | 668.28 Mn | - |
| 8 | Insmed | 27.39 Bn | 26.22 Bn | 358.27 Mn | - |
| 9 | Royalty Pharma | 27.27 Bn | 26.43 Bn | - | - |
| 10 | Karyopharm Therapeutics | 56.72 Mn | 56.72 Mn | 32.35 Mn | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -1.39 Mn |
| Dec 31, 2025 | -1.39 Mn |
| Sep 30, 2025 | 2.80 Mn |
| Sep 30, 2025 | 2.80 Mn |
| Jun 30, 2025 | -3.28 Mn |
| Jun 30, 2025 | -3.28 Mn |
| Mar 31, 2025 | 765,000.00 |
| Mar 31, 2025 | 765,000.00 |
| Dec 31, 2024 | -676,000.00 |
| Dec 31, 2024 | -676,000.00 |
| Sep 30, 2024 | 2.99 Mn |
| Sep 30, 2024 | 2.99 Mn |
| Jun 30, 2024 | -2.23 Mn |
| Jun 30, 2024 | -2.23 Mn |
| Mar 31, 2024 | 1.91 Mn |
| Mar 31, 2024 | 1.91 Mn |
| Dec 31, 2023 | 2.18 Mn |
| Dec 31, 2023 | 2.18 Mn |
| Sep 30, 2023 | -1.34 Mn |
| Sep 30, 2023 | -1.34 Mn |