Karyopharm Therapeutics (KPTI) Tax Rate (2024)
Karyopharm Therapeutics (KPTI) recorded Tax Rate of 0.07% in Q4 2025, down 0.29 percentage points from 0.35% a year earlier but up 0.17 percentage points from the prior quarter.
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Analysis
Karyopharm Therapeutics (KPTI) Tax Rate (2024) Analysis & Trends
For FY2025, Karyopharm Therapeutics reported Tax Rate of -0.02%, up 0.05 percentage points from FY2024.
- Annual Tax Rate has increased for three straight years, with a five-year change of +0.14 percentage points (FY2020 to FY2025).
- Across earlier years, Tax Rate came in at -0.07% in FY2024 (+0.15 pp), -0.23% in FY2023 (+0.02 pp), -0.24% in FY2022 (unchanged) and -0.24% in FY2021 (-0.08 pp).
- Quarterly Tax Rate has ranged from -0.39% in Q2 2023 to 0.35% in Q4 2024 over the past five years.
- On a year-over-year basis, Tax Rate has declined for three consecutive quarters, with an average year-over-year change of +0.07 percentage points over the last eight quarters.
- Peak year-over-year performance for Tax Rate in the last five years was a gain of 0.67 percentage points in Q2 2024, against a drop of 0.39 percentage points in Q2 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at -0.10% (Q3 2025), -0.11% (Q2 2025) and -0.15% (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Tax Rate (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 17.98% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 15.47% |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | - |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | - |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 14.20% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | - |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | - |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 20.98% |
| 10 | Karyopharm Therapeutics | 35.30 Mn | -191.12 Mn | 32.35 Mn | - |
API Access
Karyopharm Therapeutics Tax Rate API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=tax-rate&ticker=KPTI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "tax-rate", "ticker": "KPTI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=tax-rate&ticker=KPTI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();