Karyopharm Therapeutics (KPTI) Tax Rate (2017 - 2025)
Karyopharm Therapeutics (KPTI) reported Tax Rate of 0.07% for Q4 2025, up 16.0% on a YoY basis from 0.06% in Q4 2024, and up 27.64% quarter-over-quarter from 0.1% in Q3 2025.
Karyopharm Therapeutics (KPTI) Tax Rate (2017 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Tax Rate for 9 years, with the latest figure at 0.07% in Q4 2025.
- For the quarter ending Q4 2025, Tax Rate rose 16.0% year-over-year to 0.07%; the trailing twelve-month figure through Dec 2025 stood at 1.19% (down 7244.0% YoY), and the FY2025 full-year result was 1.19%, down 7244.0% from the prior year.
- Tax Rate for Q4 2025 stood at 0.07%, up from 0.1% in the prior quarter.
- The five-year high for Tax Rate was 0.28% in Q2 2024, with the low at 0.39% in Q2 2023.
- Historically, Tax Rate has averaged 0.16% across 5 years, with a median of 0.18% in 2021.
- Annual changes were most pronounced in 2024 — Tax Rate surged 67 bps — and 2025, when it sank 39 bps.
- Karyopharm Therapeutics' Tax Rate stood at 0.18% in 2021, then dropped by 8 bps to 0.19% in 2022, then slumped by 35 bps to 0.26% in 2023, then increased by 7 bps to 0.24% in 2024, then soared by 69 bps to 0.07% in 2025.
- The last three Tax Rate figures came in at 0.07% (Q4 2025), 0.1% (Q3 2025), and 0.11% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Tax Rate (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | -57.14% |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | 5.61% |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | -6.79% |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 17.68% |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | - |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn | -0.07% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -0.07% |
| Dec 31, 2025 | -0.07% |
| Sep 30, 2025 | -0.10% |
| Sep 30, 2025 | -0.10% |
| Jun 30, 2025 | -0.11% |
| Jun 30, 2025 | -0.11% |
| Mar 31, 2025 | -0.15% |
| Mar 31, 2025 | -0.15% |
| Dec 31, 2024 | -0.24% |
| Dec 31, 2024 | -0.24% |
| Sep 30, 2024 | -0.09% |
| Sep 30, 2024 | -0.09% |
| Jun 30, 2024 | 0.28% |
| Jun 30, 2024 | 0.28% |
| Mar 31, 2024 | -0.19% |
| Mar 31, 2024 | -0.19% |
| Dec 31, 2023 | -0.26% |
| Dec 31, 2023 | -0.26% |
| Sep 30, 2023 | -0.03% |
| Sep 30, 2023 | -0.03% |