Karyopharm Therapeutics (KPTI) Change in Accured Expenses (2012 - 2025)

Karyopharm Therapeutics (KPTI) reported Change in Accured Expenses of $1.4 million for Q4 2025, down 77.67% on a YoY basis from $6.5 million in Q4 2024, and down 84.75% quarter-over-quarter from $9.5 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Change in Accured Expenses (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Change in Accured Expenses for 14 years, with the latest figure at $1.4 million in Q4 2025.

  • For the quarter ending Q4 2025, Change in Accured Expenses fell 77.67% year-over-year to $1.4 million; the trailing twelve-month figure through Dec 2025 stood at $19.1 million (up 353.77% YoY), and the FY2025 full-year result was $19.1 million, up 353.77% from the prior year.
  • Change in Accured Expenses for Q4 2025 stood at $1.4 million, down from $9.5 million in the prior quarter.
  • The five-year high for Change in Accured Expenses was $12.1 million in Q3 2021, with the low at -$9.4 million in Q1 2023.
  • Historically, Change in Accured Expenses has averaged $1.7 million across 5 years, with a median of $2.3 million in 2022.
  • Annual changes were most pronounced in 2022 — Change in Accured Expenses tumbled 373.51% — and 2025, when it jumped 14957.89%.
  • Karyopharm Therapeutics' Change in Accured Expenses stood at $3.7 million in 2021, then plunged by 43.34% to $2.1 million in 2022, then soared by 129.16% to $4.8 million in 2023, then jumped by 35.08% to $6.5 million in 2024, then sank by 77.67% to $1.4 million in 2025.
  • The last three Change in Accured Expenses figures came in at $1.4 million (Q4 2025), $9.5 million (Q3 2025), and $8.6 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change Accured Exp. (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 931,000.00
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 644,700.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 70.50 Mn
9 Abivax 91.71 Bn 91.71 Bn - -
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 1.44 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 1.44 Mn
Dec 31, 2025 1.44 Mn
Sep 30, 2025 9.45 Mn
Sep 30, 2025 9.45 Mn
Jun 30, 2025 8.58 Mn
Jun 30, 2025 8.58 Mn
Mar 31, 2025 -412,000.00
Mar 31, 2025 -412,000.00
Dec 31, 2024 6.45 Mn
Dec 31, 2024 6.45 Mn
Sep 30, 2024 2.55 Mn
Sep 30, 2024 2.55 Mn
Jun 30, 2024 57,000.00
Jun 30, 2024 57,000.00
Mar 31, 2024 -4.86 Mn
Mar 31, 2024 -4.86 Mn
Dec 31, 2023 4.78 Mn
Dec 31, 2023 4.78 Mn
Sep 30, 2023 3.30 Mn
Sep 30, 2023 3.30 Mn