Growth Metrics

Karyopharm Therapeutics (KPTI) Return on Assets (2016 - 2025)

Karyopharm Therapeutics' Return on Assets history spans 13 years, with the latest figure at 0.04% for Q4 2025.

  • For Q4 2025, Return on Assets rose 40.0% year-over-year to 0.04%; the TTM value through Dec 2025 reached 0.04%, up 40.0%, while the annual FY2025 figure was 0.03%, 35.0% up from the prior year.
  • Return on Assets reached 0.04% in Q4 2025 per KPTI's latest filing, up from 1.24% in the prior quarter.
  • In the past five years, Return on Assets ranged from a high of 0.28% in Q3 2024 to a low of 1.24% in Q3 2025.
  • Average Return on Assets over 5 years is 0.38%, with a median of 0.43% recorded in 2024.
  • Peak YoY movement for Return on Assets: soared 77bps in 2024, then tumbled -152bps in 2025.
  • A 5-year view of Return on Assets shows it stood at 0.34% in 2021, then plummeted by -67bps to 0.56% in 2022, then skyrocketed by 100bps to 0.0% in 2023, then crashed by -145076bps to 0.43% in 2024, then soared by 92bps to 0.04% in 2025.
  • Per Business Quant, the three most recent readings for KPTI's Return on Assets are 0.04% (Q4 2025), 1.24% (Q3 2025), and 1.06% (Q2 2025).