Karyopharm Therapeutics (KPTI) Return on Assets (2013 - 2026)
Karyopharm Therapeutics' (KPTI) quarterly Return on Assets came in at 0.0% in Q4 2025, little changed YoY from 0.0% in Q4 2024, and up 176.59% on a QoQ basis from 0.0% in Q3 2025.
Karyopharm Therapeutics (KPTI) Return on Assets (2013 - 2026) Analysis & Trends
Karyopharm Therapeutics (KPTI) has 13 years of Return on Assets data on file, last reported at 0.0% in Q4 2025.
- Quarterly Return on Assets changed 0.0% year-over-year to 0.0% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 0.0% (changed 0.0% YoY) and the FY2025 annual result came in at 0.0%, changed 0.0% from the prior year.
- Return on Assets climbed to 0.0% in Q4 2025, from 0.0% in the prior quarter.
- In the past five years, Return on Assets ranged from a high of 0.0% in Q4 2025 to a low of 0.01% in Q4 2022.
- A 5-year average of 0.0% and a median of 0.0% in 2022 frame the typical range for Return on Assets.
- Annual changes were most pronounced in 2023 — Return on Assets gained 1 bps — and 2025, when it slipped 1 bps.
- Tracing KPTI's Return on Assets over 5 years: stood at 0.0% in 2021, then fell by 27 bps to 0.01% in 2022, then surged by 100 bps to 0.0% in 2023, then jumped by 144 bps to 0.0% in 2024, then soared by 282194 bps to 0.0% in 2025.
- The last three Return on Assets figures came in at 0.0% (Q4 2025), 0.0% (Q3 2025), and 0.0% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 0.00% |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 0.00% |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | - |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | 0.00% |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 0.00% |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 0.00% |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | 0.00% |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | 0.00% |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | 0.00% |
| 10 | Karyopharm Therapeutics | 53.25 Mn | 53.25 Mn | 32.35 Mn | -0.02% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -0.02% |
| Dec 31, 2025 | 0.00% |
| Sep 30, 2025 | 0.00% |
| Jun 30, 2025 | 0.00% |
| Mar 31, 2025 | 0.00% |
| Dec 31, 2024 | 0.00% |
| Sep 30, 2024 | 0.00% |
| Jun 30, 2024 | 0.00% |
| Mar 31, 2024 | 0.00% |
| Dec 31, 2023 | 0.00% |
| Sep 30, 2023 | 0.00% |
| Jun 30, 2023 | 0.00% |
| Mar 31, 2023 | 0.00% |
| Dec 31, 2022 | -0.01% |
| Sep 30, 2022 | 0.00% |
| Jun 30, 2022 | 0.00% |
| Mar 31, 2022 | 0.00% |
| Dec 31, 2021 | 0.00% |
| Sep 30, 2021 | 0.00% |
| Jun 30, 2021 | 0.00% |