Karyopharm Therapeutics (KPTI) Return on Assets (2013 - 2025)

Karyopharm Therapeutics (KPTI) reported Return on Assets of 0.0% for Q4 2025, little changed on a YoY basis from 0.0% in Q4 2024, and up 92.54% quarter-over-quarter from 0.0% in Q3 2025.

Karyopharm Therapeutics (KPTI) Return on Assets (2013 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Return on Assets for 13 years, with the latest figure at 0.0% in Q4 2025.

  • For the quarter ending Q4 2025, Return on Assets changed 0.0% year-over-year to 0.0%; the trailing twelve-month figure through Dec 2025 stood at 0.0% (changed 0.0% YoY), and the FY2025 full-year result was 0.0%, changed 0.0% from the prior year.
  • Return on Assets for Q4 2025 stood at 0.0%, up from 0.0% in the prior quarter.
  • The five-year high for Return on Assets was 0.0% in Q1 2025, with the low at 0.01% in Q1 2024.
  • Historically, Return on Assets has averaged 0.0% across 5 years, with a median of 0.0% in 2021.
  • Annual changes were most pronounced in 2021 — Return on Assets changed 0 bps — and 2024, when it gained 1 bps.
  • Karyopharm Therapeutics' Return on Assets stood at 0.0% in 2021, then sank by 67 bps to 0.01% in 2022, then rose by 0 bps to 0.01% in 2023, then jumped by 100 bps to 0.0% in 2024, then tumbled by 27588 bps to 0.0% in 2025.
  • The last three Return on Assets figures came in at 0.0% (Q4 2025), 0.0% (Q3 2025), and 0.0% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROA (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -0.80%
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -0.01%
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 0.00%
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -0.01%
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - 0.00%
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 0.00%
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 0.00%
9 Abivax 91.71 Bn 91.71 Bn - -0.01%
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 0.00%

Historic Data

Download Data
DateValue
Dec 31, 2025 0.00%
Sep 30, 2025 0.00%
Jun 30, 2025 0.00%
Mar 31, 2025 0.00%
Dec 31, 2024 0.00%
Sep 30, 2024 0.00%
Jun 30, 2024 0.00%
Mar 31, 2024 -0.01%
Dec 31, 2023 -0.01%
Sep 30, 2023 0.00%
Jun 30, 2023 0.00%
Mar 31, 2023 0.00%
Dec 31, 2022 -0.01%
Sep 30, 2022 0.00%
Jun 30, 2022 0.00%
Mar 31, 2022 0.00%
Dec 31, 2021 0.00%
Sep 30, 2021 0.00%
Jun 30, 2021 0.00%
Mar 31, 2021 0.00%