Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.82 -0.18 (-9.00%)
At close: Aug 20, 2026 · 4:00 PM EDT

Karyopharm Therapeutics (KPTI) Return on Assets (2013 - 2026)

Karyopharm Therapeutics' (KPTI) quarterly Return on Assets came in at 0.0% in Q4 2025, little changed YoY from 0.0% in Q4 2024, and up 176.59% on a QoQ basis from 0.0% in Q3 2025.

Karyopharm Therapeutics (KPTI) Return on Assets (2013 - 2026) Analysis & Trends

Karyopharm Therapeutics (KPTI) has 13 years of Return on Assets data on file, last reported at 0.0% in Q4 2025.

  • Quarterly Return on Assets changed 0.0% year-over-year to 0.0% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 0.0% (changed 0.0% YoY) and the FY2025 annual result came in at 0.0%, changed 0.0% from the prior year.
  • Return on Assets climbed to 0.0% in Q4 2025, from 0.0% in the prior quarter.
  • In the past five years, Return on Assets ranged from a high of 0.0% in Q4 2025 to a low of 0.01% in Q4 2022.
  • A 5-year average of 0.0% and a median of 0.0% in 2022 frame the typical range for Return on Assets.
  • Annual changes were most pronounced in 2023 — Return on Assets gained 1 bps — and 2025, when it slipped 1 bps.
  • Tracing KPTI's Return on Assets over 5 years: stood at 0.0% in 2021, then fell by 27 bps to 0.01% in 2022, then surged by 100 bps to 0.0% in 2023, then jumped by 144 bps to 0.0% in 2024, then soared by 282194 bps to 0.0% in 2025.
  • The last three Return on Assets figures came in at 0.0% (Q4 2025), 0.0% (Q3 2025), and 0.0% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROA (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn 0.00%
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn -
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn 0.00%
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 0.00%
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn 0.00%
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn 0.00%
8 Royalty Pharma 26.98 Bn 26.14 Bn - 0.00%
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn 0.00%
10 Karyopharm Therapeutics 53.25 Mn 53.25 Mn 32.35 Mn -0.02%

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.02%
Dec 31, 2025 0.00%
Sep 30, 2025 0.00%
Jun 30, 2025 0.00%
Mar 31, 2025 0.00%
Dec 31, 2024 0.00%
Sep 30, 2024 0.00%
Jun 30, 2024 0.00%
Mar 31, 2024 0.00%
Dec 31, 2023 0.00%
Sep 30, 2023 0.00%
Jun 30, 2023 0.00%
Mar 31, 2023 0.00%
Dec 31, 2022 -0.01%
Sep 30, 2022 0.00%
Jun 30, 2022 0.00%
Mar 31, 2022 0.00%
Dec 31, 2021 0.00%
Sep 30, 2021 0.00%
Jun 30, 2021 0.00%