Growth Metrics

Karyopharm Therapeutics (KPTI) Enterprise Value (2016 - 2025)

Karyopharm Therapeutics' Enterprise Value history spans 14 years, with the latest figure at -$50.9 million for Q4 2025.

  • For Q4 2025, Enterprise Value rose 53.14% year-over-year to -$50.9 million; the TTM value through Dec 2025 reached -$50.9 million, up 53.14%, while the annual FY2025 figure was -$50.9 million, 53.14% up from the prior year.
  • Enterprise Value reached -$50.9 million in Q4 2025 per KPTI's latest filing, down from -$43.5 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$43.5 million in Q3 2025 to a low of -$260.4 million in Q1 2023.
  • Average Enterprise Value over 5 years is -$133.3 million, with a median of -$146.1 million recorded in 2022.
  • Peak YoY movement for Enterprise Value: soared 82.14% in 2021, then plummeted 390.65% in 2023.
  • A 5-year view of Enterprise Value shows it stood at -$44.5 million in 2021, then crashed by 223.21% to -$143.8 million in 2022, then tumbled by 33.09% to -$191.4 million in 2023, then surged by 43.21% to -$108.7 million in 2024, then soared by 53.14% to -$50.9 million in 2025.
  • Per Business Quant, the three most recent readings for KPTI's Enterprise Value are -$50.9 million (Q4 2025), -$43.5 million (Q3 2025), and -$47.9 million (Q2 2025).