Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.69 -0.03 (-1.74%)
As of: Sep 9, 2026 · 3:59 PM EDT

Karyopharm Therapeutics (KPTI) Exchange Rate Effect (2015 - 2025)

Karyopharm Therapeutics' (KPTI) quarterly Exchange Rate Effect came in at $5000.0 in Q4 2025, up 125.0% on a YoY basis from $2222.2 in Q4 2024, and up 150.0% quarter-over-quarter from $2000.0 in Q3 2025.

Analysis

Karyopharm Therapeutics (KPTI) Exchange Rate Effect (2015 - 2025) Analysis & Trends

Karyopharm Therapeutics (KPTI) has reported Exchange Rate Effect for 11 consecutive years, with $5000.0 the latest figure, recorded in Q4 2025.

  • For the quarter ending Q4 2025, Exchange Rate Effect rose 125.0% year-over-year to $5000.0; the trailing twelve-month figure through Dec 2025 stood at $20000.0 (up 281.82% YoY), and the FY2025 full-year result was $20000.0, up 281.82% from the prior year.
  • Exchange Rate Effect improved to $5000.0 in Q4 2025 per KPTI's latest filing, from $2000.0 in the prior quarter.
  • Across five years, Exchange Rate Effect topped out at $242000.0 in Q3 2021 and bottomed at -$454000.0 in Q2 2022.
  • Historically, Exchange Rate Effect has averaged -$28050.0 across 5 years, with a median of -$18000.0 in 2024.
  • The sharpest annual moves came in 2021 and 2022: Exchange Rate Effect soared 1323.53% in 2021, then sank 609.38% in 2022.
  • Over 5 years, Exchange Rate Effect stood at -$135000.0 in 2021, then jumped by 193.33% to $126000.0 in 2022, then dropped by 29.37% to $89000.0 in 2023, then tumbled by 122.47% to -$20000.0 in 2024, then surged by 125.0% to $5000.0 in 2025.
  • According to Business Quant data, Exchange Rate Effect over the past three periods registered $5000.0, $2000.0, and $8000.0 for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Exchange Rate Effect (Qtr)
1 Johnson & Johnson 663.08 Bn 642.33 Bn 17.26 Bn 5.00 Mn
2 AbbVie 453.04 Bn 446.51 Bn 12.70 Bn -7.00 Mn
3 Merck 370.87 Bn 363.78 Bn 12.21 Bn -37.00 Mn
4 Novartis Ag 305.29 Bn 298.00 Bn 11.24 Bn -18.00 Mn
5 Pfizer 162.10 Bn 150.70 Bn 10.94 Bn -4.00 Mn
6 Sanofi 53.95 Bn 46.98 Bn 10.79 Bn 11.62 Mn
7 Revolution Medicines 45.00 Bn 45.00 Bn - -
8 Incyte 25.47 Bn 20.94 Bn 1.57 Bn -84,000.00
9 United Therapeutics 20.81 Bn 18.15 Bn 683.80 Mn -
10 Karyopharm Therapeutics 51.80 Mn -13.31 Mn 32.35 Mn -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 5,000.00
Sep 30, 2025 2,000.00
Jun 30, 2025 8,000.00
Mar 31, 2025 5,000.00
Dec 31, 2024 -20,000.00
Sep 30, 2024 36,000.00
Jun 30, 2024 -11,000.00
Mar 31, 2024 -16,000.00
Dec 31, 2023 89,000.00
Sep 30, 2023 -52,000.00
Jun 30, 2023 -26,000.00
Mar 31, 2023 -45,000.00
Dec 31, 2022 126,000.00
Sep 30, 2022 -70,000.00
Jun 30, 2022 -454,000.00
Mar 31, 2022 -90,000.00
Dec 31, 2021 -135,000.00
Sep 30, 2021 242,000.00
Jun 30, 2021 -64,000.00
Mar 31, 2021 -91,000.00