Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.82 -0.18 (-9.00%)
At close: Aug 20, 2026 · 4:00 PM EDT

Karyopharm Therapeutics (KPTI) Exchange Rate Effect (2015 - 2025)

Karyopharm Therapeutics' (KPTI) quarterly Exchange Rate Effect came in at $5000.0 in Q4 2025, up 125.0% YoY from $2222.2 in Q4 2024, and up 150.0% on a QoQ basis from $2000.0 in Q3 2025.

Karyopharm Therapeutics (KPTI) Exchange Rate Effect (2015 - 2025) Analysis & Trends

Karyopharm Therapeutics (KPTI) has 11 years of Exchange Rate Effect data on file, last reported at $5000.0 in Q4 2025.

  • Quarterly Exchange Rate Effect rose 125.0% year-over-year to $5000.0 in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $20000.0 (up 281.82% YoY) and the FY2025 annual result came in at $20000.0, up 281.82% from the prior year.
  • Exchange Rate Effect grew to $5000.0 in Q4 2025, from $2000.0 in the prior quarter.
  • In the past five years, Exchange Rate Effect ranged from a high of $242000.0 in Q3 2021 to a low of -$454000.0 in Q2 2022.
  • A 5-year average of -$28050.0 and a median of -$18000.0 in 2024 frame the typical range for Exchange Rate Effect.
  • Annual changes were most pronounced in 2021 — Exchange Rate Effect surged 1323.53% — and 2022, when it plunged 609.38%.
  • Tracing KPTI's Exchange Rate Effect over 5 years: stood at -$135000.0 in 2021, then surged by 193.33% to $126000.0 in 2022, then decreased by 29.37% to $89000.0 in 2023, then sank by 122.47% to -$20000.0 in 2024, then soared by 125.0% to $5000.0 in 2025.
  • The last three Exchange Rate Effect figures came in at $5000.0 (Q4 2025), $2000.0 (Q3 2025), and $8000.0 (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Exchange Rate Effect (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn -3.70 Mn
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn -300,000.00
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn -
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn -2.00 Mn
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 19.84 Mn
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn -2.45 Mn
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn -287,000.00
8 Royalty Pharma 26.98 Bn 26.14 Bn - -
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn 1.63 Mn
10 Karyopharm Therapeutics 53.25 Mn 53.25 Mn 32.35 Mn -

Historic Data

Download Data
DateValue
Dec 31, 2025 5,000.00
Dec 31, 2025 5,000.00
Sep 30, 2025 2,000.00
Sep 30, 2025 2,000.00
Jun 30, 2025 8,000.00
Jun 30, 2025 8,000.00
Mar 31, 2025 5,000.00
Mar 31, 2025 5,000.00
Dec 31, 2024 -20,000.00
Dec 31, 2024 -20,000.00
Sep 30, 2024 36,000.00
Sep 30, 2024 36,000.00
Jun 30, 2024 -11,000.00
Jun 30, 2024 -11,000.00
Mar 31, 2024 -16,000.00
Mar 31, 2024 -16,000.00
Dec 31, 2023 89,000.00
Dec 31, 2023 89,000.00
Sep 30, 2023 -52,000.00
Sep 30, 2023 -52,000.00