Karyopharm Therapeutics (KPTI) Exchange Rate Effect (2015 - 2025)
Karyopharm Therapeutics' (KPTI) quarterly Exchange Rate Effect came in at $5000.0 in Q4 2025, up 125.0% on a YoY basis from $2222.2 in Q4 2024, and up 150.0% quarter-over-quarter from $2000.0 in Q3 2025.
Analysis
Karyopharm Therapeutics (KPTI) Exchange Rate Effect (2015 - 2025) Analysis & Trends
Karyopharm Therapeutics (KPTI) has reported Exchange Rate Effect for 11 consecutive years, with $5000.0 the latest figure, recorded in Q4 2025.
- For the quarter ending Q4 2025, Exchange Rate Effect rose 125.0% year-over-year to $5000.0; the trailing twelve-month figure through Dec 2025 stood at $20000.0 (up 281.82% YoY), and the FY2025 full-year result was $20000.0, up 281.82% from the prior year.
- Exchange Rate Effect improved to $5000.0 in Q4 2025 per KPTI's latest filing, from $2000.0 in the prior quarter.
- Across five years, Exchange Rate Effect topped out at $242000.0 in Q3 2021 and bottomed at -$454000.0 in Q2 2022.
- Historically, Exchange Rate Effect has averaged -$28050.0 across 5 years, with a median of -$18000.0 in 2024.
- The sharpest annual moves came in 2021 and 2022: Exchange Rate Effect soared 1323.53% in 2021, then sank 609.38% in 2022.
- Over 5 years, Exchange Rate Effect stood at -$135000.0 in 2021, then jumped by 193.33% to $126000.0 in 2022, then dropped by 29.37% to $89000.0 in 2023, then tumbled by 122.47% to -$20000.0 in 2024, then surged by 125.0% to $5000.0 in 2025.
- According to Business Quant data, Exchange Rate Effect over the past three periods registered $5000.0, $2000.0, and $8000.0 for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Exchange Rate Effect (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 663.08 Bn | 642.33 Bn | 17.26 Bn | 5.00 Mn |
| 2 | AbbVie | 453.04 Bn | 446.51 Bn | 12.70 Bn | -7.00 Mn |
| 3 | Merck | 370.87 Bn | 363.78 Bn | 12.21 Bn | -37.00 Mn |
| 4 | Novartis Ag | 305.29 Bn | 298.00 Bn | 11.24 Bn | -18.00 Mn |
| 5 | Pfizer | 162.10 Bn | 150.70 Bn | 10.94 Bn | -4.00 Mn |
| 6 | Sanofi | 53.95 Bn | 46.98 Bn | 10.79 Bn | 11.62 Mn |
| 7 | Revolution Medicines | 45.00 Bn | 45.00 Bn | - | - |
| 8 | Incyte | 25.47 Bn | 20.94 Bn | 1.57 Bn | -84,000.00 |
| 9 | United Therapeutics | 20.81 Bn | 18.15 Bn | 683.80 Mn | - |
| 10 | Karyopharm Therapeutics | 51.80 Mn | -13.31 Mn | 32.35 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 5,000.00 |
| Sep 30, 2025 | 2,000.00 |
| Jun 30, 2025 | 8,000.00 |
| Mar 31, 2025 | 5,000.00 |
| Dec 31, 2024 | -20,000.00 |
| Sep 30, 2024 | 36,000.00 |
| Jun 30, 2024 | -11,000.00 |
| Mar 31, 2024 | -16,000.00 |
| Dec 31, 2023 | 89,000.00 |
| Sep 30, 2023 | -52,000.00 |
| Jun 30, 2023 | -26,000.00 |
| Mar 31, 2023 | -45,000.00 |
| Dec 31, 2022 | 126,000.00 |
| Sep 30, 2022 | -70,000.00 |
| Jun 30, 2022 | -454,000.00 |
| Mar 31, 2022 | -90,000.00 |
| Dec 31, 2021 | -135,000.00 |
| Sep 30, 2021 | 242,000.00 |
| Jun 30, 2021 | -64,000.00 |
| Mar 31, 2021 | -91,000.00 |