Karyopharm Therapeutics (KPTI) Depreciation & Amortization (CF) (2012 - 2025)
Karyopharm Therapeutics (KPTI) posted Depreciation & Amortization (CF) of $19,000 for Q4 2025, down 76.5% from $81,000 a year earlier and down 84.3% from the prior quarter.
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Analysis
Karyopharm Therapeutics (KPTI) Depreciation & Amortization (CF) (2012 - 2025) Analysis & Trends
For FY2025, Karyopharm Therapeutics' Depreciation & Amortization (CF) came in at $296,000, down 12.9% from FY2024.
- Annual Depreciation & Amortization (CF) has declined for six consecutive years, with a five-year compound annual growth rate of -21.2% (FY2020 to FY2025).
- In prior years, Karyopharm Therapeutics' Depreciation & Amortization (CF) was $340,000 in FY2024 (-35.8%), $530,000 in FY2023 (-14.7%), $621,000 in FY2022 (-21.3%) and $789,000 in FY2021 (-18.8%).
- The Q4 2025 figure stands as the lowest quarterly Depreciation & Amortization (CF) in data going back to Q4 2012.
- On a year-over-year basis, Depreciation & Amortization (CF) increased in four of the last eight quarters, with an average decline of 13.2%.
- The strongest year-over-year quarter for Depreciation & Amortization (CF) in the past five years was Q1 2023, with growth of 63.8%; the weakest was Q4 2025, with a decline of 76.5%.
- According to Business Quant data, Depreciation & Amortization (CF) for the three prior quarters was $121,000 (Q3 2025), $78,000 (Q2 2025) and $78,000 (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Dep. & Amort. (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,082.65 Bn | 1,051.23 Bn | 19.71 Bn | 534.00 Mn |
| 2 | Johnson & Johnson | 623.68 Bn | 542.21 Bn | 17.26 Bn | 1.96 Bn |
| 3 | AbbVie | 459.43 Bn | 432.59 Bn | 12.70 Bn | 194.00 Mn |
| 4 | Merck | 354.80 Bn | 309.23 Bn | 12.21 Bn | 599.00 Mn |
| 5 | Novartis Ag | 269.16 Bn | 225.03 Bn | 11.24 Bn | - |
| 6 | Astrazeneca | 244.40 Bn | 217.97 Bn | 12.86 Bn | 1.93 Bn |
| 7 | Amgen | 220.17 Bn | 175.57 Bn | 7.24 Bn | 1.11 Bn |
| 8 | Gilead Sciences | 183.05 Bn | 157.16 Bn | 6.22 Bn | 98.00 Mn |
| 9 | Pfizer | 160.27 Bn | 107.22 Bn | 10.94 Bn | 1.62 Bn |
| 10 | Karyopharm Therapeutics | 25.18 Mn | -201.25 Mn | 32.35 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 19,000.00 |
| Sep 30, 2025 | 121,000.00 |
| Jun 30, 2025 | 78,000.00 |
| Mar 31, 2025 | 78,000.00 |
| Dec 31, 2024 | 81,000.00 |
| Sep 30, 2024 | 83,000.00 |
| Jun 30, 2024 | 91,000.00 |
| Mar 31, 2024 | 85,000.00 |
| Dec 31, 2023 | 77,000.00 |
| Sep 30, 2023 | 80,000.00 |
| Jun 30, 2023 | 83,000.00 |
| Mar 31, 2023 | 290,000.00 |
| Dec 31, 2022 | 113,000.00 |
| Sep 30, 2022 | 182,000.00 |
| Jun 30, 2022 | 149,000.00 |
| Mar 31, 2022 | 177,000.00 |
| Dec 31, 2021 | 139,000.00 |
| Sep 30, 2021 | 186,000.00 |
| Jun 30, 2021 | 229,000.00 |
| Mar 31, 2021 | 235,000.00 |
API Access
Karyopharm Therapeutics Depreciation & Amortization (CF) API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=depreciation-and-amortization-cf&ticker=KPTI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "depreciation-and-amortization-cf", "ticker": "KPTI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=depreciation-and-amortization-cf&ticker=KPTI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();