Karyopharm Therapeutics (KPTI) Net Income towards Common Stockholders (2012 - 2025)

Karyopharm Therapeutics (KPTI) reported Net Income towards Common Stockholders of $90.2 million for Q4 2025, up 97.49% on a YoY basis from $45.7 million in Q4 2024, and up 372.24% quarter-over-quarter from -$33.1 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Net Income towards Common Stockholders (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Net Income towards Common Stockholders for 14 years, with the latest figure at $90.2 million in Q4 2025.

  • For the quarter ending Q4 2025, Net Income towards Common Stockholders rose 97.49% year-over-year to $90.2 million; the trailing twelve-month figure through Dec 2025 stood at -$3.7 million (down 15995.65% YoY), and the FY2025 full-year result was -$3.7 million, down 15995.65% from the prior year.
  • Net Income towards Common Stockholders for Q4 2025 stood at $90.2 million, up from -$33.1 million in the prior quarter.
  • The five-year high for Net Income towards Common Stockholders was $90.2 million in Q4 2025, with the low at -$57.4 million in Q1 2021.
  • Historically, Net Income towards Common Stockholders has averaged -$20.3 million across 5 years, with a median of -$35.4 million in 2022.
  • Annual changes were most pronounced in 2024 — Net Income towards Common Stockholders soared 209.21% — and 2025, when it slumped 256.57%.
  • Karyopharm Therapeutics' Net Income towards Common Stockholders stood at $68.8 million in 2021, then slumped by 155.99% to -$38.5 million in 2022, then declined by 8.59% to -$41.8 million in 2023, then soared by 209.21% to $45.7 million in 2024, then jumped by 97.49% to $90.2 million in 2025.
  • The last three Net Income towards Common Stockholders figures came in at $90.2 million (Q4 2025), -$33.1 million (Q3 2025), and -$37.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -13.56 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 2.50 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -14.46 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.63 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -1.50 Mn
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.03 Bn
9 Abivax 91.71 Bn 91.71 Bn - -56.48 Mn
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 90.19 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 90.19 Mn
Sep 30, 2025 -33.13 Mn
Jun 30, 2025 -37.25 Mn
Mar 31, 2025 -23.46 Mn
Dec 31, 2024 45.67 Mn
Sep 30, 2024 -32.07 Mn
Jun 30, 2024 23.79 Mn
Mar 31, 2024 -37.36 Mn
Dec 31, 2023 -41.81 Mn
Sep 30, 2023 -34.51 Mn
Jun 30, 2023 -32.63 Mn
Mar 31, 2023 -34.13 Mn
Dec 31, 2022 -38.51 Mn
Sep 30, 2022 -36.32 Mn
Jun 30, 2022 -49.06 Mn
Mar 31, 2022 -41.40 Mn
Dec 31, 2021 68.77 Mn
Sep 30, 2021 -51.81 Mn
Jun 30, 2021 -53.58 Mn
Mar 31, 2021 -57.41 Mn