Karyopharm Therapeutics (KPTI) Short-term Investments (2014 - 2025)
Karyopharm Therapeutics (KPTI) reported Short-term Investments of $3.2 million for Q4 2025, down 93.07% on a YoY basis from $46.2 million in Q4 2024, and down 60.95% quarter-over-quarter from $8.2 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Short-term Investments (2014 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Short-term Investments for 12 years, with the latest figure at $3.2 million in Q4 2025.
- For the quarter ending Q4 2025, Short-term Investments fell 93.07% year-over-year to $3.2 million; the trailing twelve-month figure through Dec 2025 stood at $3.2 million (down 93.07% YoY), and the FY2025 full-year result was $3.2 million, down 93.07% from the prior year.
- Short-term Investments for Q4 2025 stood at $3.2 million, down from $8.2 million in the prior quarter.
- The five-year high for Short-term Investments was $176.3 million in Q1 2023, with the low at $3.2 million in Q4 2025.
- Historically, Short-term Investments has averaged $84.0 million across 5 years, with a median of $72.2 million in 2022.
- Annual changes were most pronounced in 2022 — Short-term Investments surged 274.2% — and 2025, when it slumped 93.07%.
- Karyopharm Therapeutics' Short-term Investments stood at $38.2 million in 2021, then surged by 274.2% to $142.8 million in 2022, then slipped by 2.5% to $139.2 million in 2023, then slumped by 66.79% to $46.2 million in 2024, then tumbled by 93.07% to $3.2 million in 2025.
- The last three Short-term Investments figures came in at $3.2 million (Q4 2025), $8.2 million (Q3 2025), and $13.0 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 3.20 Mn |
| Sep 30, 2025 | 8.21 Mn |
| Jun 30, 2025 | 12.97 Mn |
| Mar 31, 2025 | 31.16 Mn |
| Dec 31, 2024 | 46.24 Mn |
| Sep 30, 2024 | 60.70 Mn |
| Jun 30, 2024 | 67.35 Mn |
| Mar 31, 2024 | 117.95 Mn |
| Dec 31, 2023 | 139.21 Mn |
| Sep 30, 2023 | 164.66 Mn |
| Jun 30, 2023 | 155.87 Mn |
| Mar 31, 2023 | 176.32 Mn |
| Dec 31, 2022 | 142.78 Mn |
| Sep 30, 2022 | 77.03 Mn |
| Jun 30, 2022 | 88.60 Mn |
| Mar 31, 2022 | 52.06 Mn |
| Dec 31, 2021 | 38.16 Mn |
| Sep 30, 2021 | 66.81 Mn |
| Jun 30, 2021 | 94.58 Mn |
| Mar 31, 2021 | 135.89 Mn |