Karyopharm Therapeutics (KPTI) Short-term Investments (2014 - 2025)

Karyopharm Therapeutics (KPTI) reported Short-term Investments of $3.2 million for Q4 2025, down 93.07% on a YoY basis from $46.2 million in Q4 2024, and down 60.95% quarter-over-quarter from $8.2 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Short-term Investments (2014 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Short-term Investments for 12 years, with the latest figure at $3.2 million in Q4 2025.

  • For the quarter ending Q4 2025, Short-term Investments fell 93.07% year-over-year to $3.2 million; the trailing twelve-month figure through Dec 2025 stood at $3.2 million (down 93.07% YoY), and the FY2025 full-year result was $3.2 million, down 93.07% from the prior year.
  • Short-term Investments for Q4 2025 stood at $3.2 million, down from $8.2 million in the prior quarter.
  • The five-year high for Short-term Investments was $176.3 million in Q1 2023, with the low at $3.2 million in Q4 2025.
  • Historically, Short-term Investments has averaged $84.0 million across 5 years, with a median of $72.2 million in 2022.
  • Annual changes were most pronounced in 2022 — Short-term Investments surged 274.2% — and 2025, when it slumped 93.07%.
  • Karyopharm Therapeutics' Short-term Investments stood at $38.2 million in 2021, then surged by 274.2% to $142.8 million in 2022, then slipped by 2.5% to $139.2 million in 2023, then slumped by 66.79% to $46.2 million in 2024, then tumbled by 93.07% to $3.2 million in 2025.
  • The last three Short-term Investments figures came in at $3.2 million (Q4 2025), $8.2 million (Q3 2025), and $13.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn -
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn -
6 Evaxion A 1,551.28 Bn 1,551.26 Bn -
7 Psyence Biomedical 227.32 Bn 227.31 Bn -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn
9 Abivax 91.71 Bn 91.71 Bn -
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 3.20 Mn
Sep 30, 2025 8.21 Mn
Jun 30, 2025 12.97 Mn
Mar 31, 2025 31.16 Mn
Dec 31, 2024 46.24 Mn
Sep 30, 2024 60.70 Mn
Jun 30, 2024 67.35 Mn
Mar 31, 2024 117.95 Mn
Dec 31, 2023 139.21 Mn
Sep 30, 2023 164.66 Mn
Jun 30, 2023 155.87 Mn
Mar 31, 2023 176.32 Mn
Dec 31, 2022 142.78 Mn
Sep 30, 2022 77.03 Mn
Jun 30, 2022 88.60 Mn
Mar 31, 2022 52.06 Mn
Dec 31, 2021 38.16 Mn
Sep 30, 2021 66.81 Mn
Jun 30, 2021 94.58 Mn
Mar 31, 2021 135.89 Mn