Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.96 +0.14 (+7.69%)
At close: Aug 21, 2026 · 4:00 PM EDT

Karyopharm Therapeutics (KPTI) Short-term Investments (2014 - 2026)

Karyopharm Therapeutics' (KPTI) quarterly Short-term Investments came in at $3.2 million in Q4 2025, down 93.07% YoY from $46.2 million in Q4 2024, and down 60.95% on a QoQ basis from $8.2 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Short-term Investments (2014 - 2026) Analysis & Trends

Karyopharm Therapeutics (KPTI) has 12 years of Short-term Investments data on file, last reported at $3.2 million in Q4 2025.

  • Quarterly Short-term Investments fell 93.07% year-over-year to $3.2 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $3.2 million (down 93.07% YoY) and the FY2025 annual result came in at $3.2 million, down 93.07% from the prior year.
  • Short-term Investments declined to $3.2 million in Q4 2025, from $8.2 million in the prior quarter.
  • In the past five years, Short-term Investments ranged from a high of $176.3 million in Q1 2023 to a low of $3.2 million in Q4 2025.
  • A 5-year average of $84.0 million and a median of $72.2 million in 2022 frame the typical range for Short-term Investments.
  • Annual changes were most pronounced in 2022 — Short-term Investments surged 274.2% — and 2025, when it slumped 93.07%.
  • Tracing KPTI's Short-term Investments over 5 years: stood at $38.2 million in 2021, then surged by 274.2% to $142.8 million in 2022, then slipped by 2.5% to $139.2 million in 2023, then slumped by 66.79% to $46.2 million in 2024, then tumbled by 93.07% to $3.2 million in 2025.
  • The last three Short-term Investments figures came in at $3.2 million (Q4 2025), $8.2 million (Q3 2025), and $13.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn -
10 Karyopharm Therapeutics 56.72 Mn 56.72 Mn 32.35 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 10.13 Mn
Dec 31, 2025 3.20 Mn
Sep 30, 2025 8.21 Mn
Jun 30, 2025 12.97 Mn
Mar 31, 2025 31.16 Mn
Dec 31, 2024 46.24 Mn
Sep 30, 2024 60.70 Mn
Jun 30, 2024 67.35 Mn
Mar 31, 2024 117.95 Mn
Dec 31, 2023 139.21 Mn
Sep 30, 2023 164.66 Mn
Jun 30, 2023 155.87 Mn
Mar 31, 2023 176.32 Mn
Dec 31, 2022 142.78 Mn
Sep 30, 2022 77.03 Mn
Jun 30, 2022 88.60 Mn
Mar 31, 2022 52.06 Mn
Dec 31, 2021 38.16 Mn
Sep 30, 2021 66.81 Mn
Jun 30, 2021 94.58 Mn