Karyopharm Therapeutics (KPTI) Short-term Investments (2014 - 2026)
Karyopharm Therapeutics' (KPTI) quarterly Short-term Investments came in at $3.2 million in Q4 2025, down 93.07% YoY from $46.2 million in Q4 2024, and down 60.95% on a QoQ basis from $8.2 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Short-term Investments (2014 - 2026) Analysis & Trends
Karyopharm Therapeutics (KPTI) has 12 years of Short-term Investments data on file, last reported at $3.2 million in Q4 2025.
- Quarterly Short-term Investments fell 93.07% year-over-year to $3.2 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $3.2 million (down 93.07% YoY) and the FY2025 annual result came in at $3.2 million, down 93.07% from the prior year.
- Short-term Investments declined to $3.2 million in Q4 2025, from $8.2 million in the prior quarter.
- In the past five years, Short-term Investments ranged from a high of $176.3 million in Q1 2023 to a low of $3.2 million in Q4 2025.
- A 5-year average of $84.0 million and a median of $72.2 million in 2022 frame the typical range for Short-term Investments.
- Annual changes were most pronounced in 2022 — Short-term Investments surged 274.2% — and 2025, when it slumped 93.07%.
- Tracing KPTI's Short-term Investments over 5 years: stood at $38.2 million in 2021, then surged by 274.2% to $142.8 million in 2022, then slipped by 2.5% to $139.2 million in 2023, then slumped by 66.79% to $46.2 million in 2024, then tumbled by 93.07% to $3.2 million in 2025.
- The last three Short-term Investments figures came in at $3.2 million (Q4 2025), $8.2 million (Q3 2025), and $13.0 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.13 Bn | 131.28 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.77 Bn | 77.77 Bn | 3.93 Bn |
| 3 | Argenx Se | 64.64 Bn | 59.46 Bn | 1.37 Bn |
| 4 | Moderna | 58.29 Bn | 53.16 Bn | 52.00 Mn |
| 5 | BeOne Medicines | 41.92 Bn | 36.82 Bn | 1.53 Bn |
| 6 | Alnylam Pharmaceuticals | 31.58 Bn | 28.28 Bn | 992.69 Mn |
| 7 | BioNTech SE | 28.12 Bn | 9.73 Bn | 668.28 Mn |
| 8 | Insmed | 27.39 Bn | 26.22 Bn | 358.27 Mn |
| 9 | Royalty Pharma | 27.27 Bn | 26.43 Bn | - |
| 10 | Karyopharm Therapeutics | 56.72 Mn | 56.72 Mn | 32.35 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 10.13 Mn |
| Dec 31, 2025 | 3.20 Mn |
| Sep 30, 2025 | 8.21 Mn |
| Jun 30, 2025 | 12.97 Mn |
| Mar 31, 2025 | 31.16 Mn |
| Dec 31, 2024 | 46.24 Mn |
| Sep 30, 2024 | 60.70 Mn |
| Jun 30, 2024 | 67.35 Mn |
| Mar 31, 2024 | 117.95 Mn |
| Dec 31, 2023 | 139.21 Mn |
| Sep 30, 2023 | 164.66 Mn |
| Jun 30, 2023 | 155.87 Mn |
| Mar 31, 2023 | 176.32 Mn |
| Dec 31, 2022 | 142.78 Mn |
| Sep 30, 2022 | 77.03 Mn |
| Jun 30, 2022 | 88.60 Mn |
| Mar 31, 2022 | 52.06 Mn |
| Dec 31, 2021 | 38.16 Mn |
| Sep 30, 2021 | 66.81 Mn |
| Jun 30, 2021 | 94.58 Mn |