Karyopharm Therapeutics (KPTI) Operating Leases (2019 - 2025)
Karyopharm Therapeutics (KPTI) reported Operating Leases of $5.7 million for Q4 2025, down 14.44% on a YoY basis from $6.7 million in Q4 2024, and down 4.41% quarter-over-quarter from $6.0 million in Q3 2025.
Karyopharm Therapeutics (KPTI) Operating Leases (2019 - 2025) Analysis & Trends
Karyopharm Therapeutics has reported Operating Leases for 7 years, with the latest figure at $5.7 million in Q4 2025.
- For the quarter ending Q4 2025, Operating Leases fell 14.44% year-over-year to $5.7 million; the trailing twelve-month figure through Dec 2025 stood at $5.7 million (down 14.44% YoY), and the FY2025 full-year result was $5.7 million, down 14.44% from the prior year.
- Operating Leases for Q4 2025 stood at $5.7 million, down from $6.0 million in the prior quarter.
- The five-year high for Operating Leases was $10.7 million in Q1 2021, with the low at $955000.0 in Q2 2024.
- Historically, Operating Leases has averaged $6.2 million across 5 years, with a median of $6.3 million in 2025.
- Annual changes were most pronounced in 2024 — Operating Leases slumped 78.78% — and 2025, when it surged 554.55%.
- Karyopharm Therapeutics' Operating Leases stood at $9.0 million in 2021, then sank by 32.02% to $6.1 million in 2022, then sank by 54.26% to $2.8 million in 2023, then surged by 140.66% to $6.7 million in 2024, then dropped by 14.44% to $5.7 million in 2025.
- The last three Operating Leases figures came in at $5.7 million (Q4 2025), $6.0 million (Q3 2025), and $6.3 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - |
| 10 | Karyopharm Therapeutics | 95.31 Mn | 31.56 Mn | 32.74 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 5.74 Mn |
| Sep 30, 2025 | 6.01 Mn |
| Jun 30, 2025 | 6.25 Mn |
| Mar 31, 2025 | 6.49 Mn |
| Dec 31, 2024 | 6.71 Mn |
| Jun 30, 2024 | 955,000.00 |
| Mar 31, 2024 | 1.88 Mn |
| Dec 31, 2023 | 2.79 Mn |
| Sep 30, 2023 | 3.67 Mn |
| Jun 30, 2023 | 4.50 Mn |
| Mar 31, 2023 | 5.31 Mn |
| Dec 31, 2022 | 6.10 Mn |
| Sep 30, 2022 | 6.86 Mn |
| Jun 30, 2022 | 7.58 Mn |
| Mar 31, 2022 | 8.29 Mn |
| Dec 31, 2021 | 8.97 Mn |
| Sep 30, 2021 | 9.63 Mn |
| Jun 30, 2021 | 10.20 Mn |
| Mar 31, 2021 | 10.75 Mn |
| Dec 31, 2020 | 11.29 Mn |