Karyopharm Therapeutics (KPTI) Debt Ratio (2024 - 2025)

Karyopharm Therapeutics (KPTI) reported Debt Ratio of 1.07 for Q4 2025, up 85.64% on a YoY basis from 0.58 in Q4 2024, and up 6.63% quarter-over-quarter from 1.0 in Q3 2025.

Karyopharm Therapeutics (KPTI) Debt Ratio (2024 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Debt Ratio for 2 years, with the latest figure at 1.07 in Q4 2025.

  • For the quarter ending Q4 2025, Debt Ratio rose 85.64% year-over-year to 1.07; the trailing twelve-month figure through Dec 2025 stood at 1.07 (up 85.64% YoY), and the FY2025 full-year result was 1.07, up 85.64% from the prior year.
  • Debt Ratio for Q4 2025 stood at 1.07, up from 1.0 in the prior quarter.
  • The five-year high for Debt Ratio was 1.07 in Q4 2025, with the low at 0.44 in Q2 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Debt Ratio (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 0.18
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn -
9 Abivax 91.71 Bn 91.71 Bn - -
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 1.07

Historic Data

Download Data
DateValue
Dec 31, 2025 1.07
Sep 30, 2025 1.00
Jun 30, 2025 0.91
Mar 31, 2025 0.75
Dec 31, 2024 0.58
Sep 30, 2024 0.50
Jun 30, 2024 0.44