Karyopharm Therapeutics KPTI
NASDAQ KPTI
$1.61 -0.08 (-4.73%)
As of: Sep 10, 2026 · 12:02 PM EDT

Karyopharm Therapeutics (KPTI) Debt Ratio (2024 - 2026)

Karyopharm Therapeutics' (KPTI) quarterly Debt Ratio came in at 1.13 in Q2 2026, up 23.26% on a YoY basis from 0.91 in Q2 2025, and up 5.42% quarter-over-quarter from 1.07 in Q4 2025.

Analysis

Karyopharm Therapeutics (KPTI) Debt Ratio (2024 - 2026) Analysis & Trends

Karyopharm Therapeutics (KPTI) has reported Debt Ratio for 3 consecutive years, with 1.13 the latest figure, recorded in Q2 2026.

  • For the quarter ending Q2 2026, Debt Ratio rose 23.26% year-over-year to 1.13; the trailing twelve-month figure through Jun 2026 stood at 1.13 (up 23.26% YoY), and the FY2025 full-year result was 1.07, up 85.64% from the prior year.
  • Debt Ratio grew to 1.13 in Q2 2026 per KPTI's latest filing, from 1.07 in the prior quarter.
  • Across five years, Debt Ratio topped out at 1.13 in Q2 2026 and bottomed at 0.44 in Q2 2024.
  • Historically, Debt Ratio has averaged 0.8 across 3 years, with a median of 0.83 in 2025.
  • The sharpest annual moves came in 2025 and 2026: Debt Ratio jumped 109.04% in 2025, then advanced 23.26% in 2026.
  • Over 3 years, Debt Ratio stood at 0.58 in 2024, then soared by 85.64% to 1.07 in 2025, then gained by 5.42% to 1.13 in 2026.
  • According to Business Quant data, Debt Ratio over the past three periods registered 1.13, 1.07, and 1.0 for Q2 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Debt Ratio (Qtr)
1 Johnson & Johnson 641.14 Bn 620.38 Bn 17.26 Bn 0.30
2 AbbVie 446.62 Bn 440.05 Bn 12.70 Bn 0.52
3 Merck 358.24 Bn 351.10 Bn 12.21 Bn 0.42
4 Novartis Ag 268.40 Bn 260.71 Bn 11.24 Bn 0.08
5 Pfizer 157.04 Bn 145.34 Bn 10.94 Bn 0.31
6 Sanofi 52.18 Bn 44.80 Bn 10.79 Bn 0.17
7 Revolution Medicines 42.98 Bn 42.98 Bn - -
8 Incyte 24.83 Bn 20.30 Bn 1.57 Bn 0.00
9 United Therapeutics 21.38 Bn 18.72 Bn 683.80 Mn -
10 Karyopharm Therapeutics 46.73 Mn -18.37 Mn 32.35 Mn 1.13
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 1.13
Dec 31, 2025 1.07
Sep 30, 2025 1.00
Jun 30, 2025 0.91
Mar 31, 2025 0.75
Dec 31, 2024 0.58
Sep 30, 2024 0.50
Jun 30, 2024 0.44