Karyopharm Therapeutics (KPTI) Other Working Capital Changes (2012 - 2025)

Karyopharm Therapeutics (KPTI) reported Other Working Capital Changes of $93000.0 for Q4 2025, up 103.72% on a YoY basis from $45651.2 in Q4 2024, and up 141.7% quarter-over-quarter from -$223000.0 in Q3 2025.

Karyopharm Therapeutics (KPTI) Other Working Capital Changes (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Other Working Capital Changes for 14 years, with the latest figure at $93000.0 in Q4 2025.

  • For the quarter ending Q4 2025, Other Working Capital Changes rose 103.72% year-over-year to $93000.0; the trailing twelve-month figure through Dec 2025 stood at -$4.1 million (down 1055.09% YoY), and the FY2025 full-year result was $202864.0, up 147.4% from the prior year.
  • Other Working Capital Changes for Q4 2025 stood at $93000.0, up from -$223000.0 in the prior quarter.
  • The five-year high for Other Working Capital Changes was $15.6 million in Q1 2022, with the low at -$16.7 million in Q2 2022.
  • Historically, Other Working Capital Changes has averaged -$325150.0 across 5 years, with a median of -$692500.0 in 2023.
  • The largest YoY upside for Other Working Capital Changes was 5352.53% in 2022 against a maximum downside of 2561.24% in 2022.
  • Karyopharm Therapeutics' Other Working Capital Changes stood at -$1.6 million in 2021, then tumbled by 35.49% to -$2.2 million in 2022, then surged by 51.62% to -$1.1 million in 2023, then slumped by 135.5% to -$2.5 million in 2024, then jumped by 103.72% to $93000.0 in 2025.
  • The last three Other Working Capital Changes figures came in at $93000.0 (Q4 2025), -$223000.0 (Q3 2025), and -$2.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn -
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn -
6 Evaxion A 1,551.28 Bn 1,551.26 Bn -
7 Psyence Biomedical 227.32 Bn 227.31 Bn -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn
9 Abivax 91.71 Bn 91.71 Bn -
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 93,000.00
Dec 31, 2025 93,000.00
Sep 30, 2025 -223,000.00
Sep 30, 2025 -223,000.00
Jun 30, 2025 -2.04 Mn
Jun 30, 2025 -2.04 Mn
Mar 31, 2025 -1.96 Mn
Mar 31, 2025 -1.96 Mn
Dec 31, 2024 -2.50 Mn
Dec 31, 2024 -2.50 Mn
Sep 30, 2024 4.53 Mn
Sep 30, 2024 4.53 Mn
Jun 30, 2024 -5.26 Mn
Jun 30, 2024 -5.26 Mn
Mar 31, 2024 3.67 Mn
Mar 31, 2024 3.67 Mn
Dec 31, 2023 -1.06 Mn
Dec 31, 2023 -1.06 Mn
Sep 30, 2023 -4.23 Mn
Sep 30, 2023 -4.23 Mn