Karyopharm Therapeutics (KPTI) Liabilities and Shareholders Equity (2012 - 2025)

Karyopharm Therapeutics (KPTI) reported Liabilities and Shareholders Equity of $108.4 million for Q4 2025, down 34.06% on a YoY basis from $164.4 million in Q4 2024, and up 12.66% quarter-over-quarter from $96.2 million in Q3 2025.

Karyopharm Therapeutics (KPTI) Liabilities and Shareholders Equity (2012 - 2025) Analysis & Trends

Karyopharm Therapeutics has reported Liabilities and Shareholders Equity for 14 years, with the latest figure at $108.4 million in Q4 2025.

  • For the quarter ending Q4 2025, Liabilities and Shareholders Equity fell 34.06% year-over-year to $108.4 million; the trailing twelve-month figure through Dec 2025 stood at $437.2 million (down 43.39% YoY), and the FY2025 full-year result was $108.4 million, down 34.06% from the prior year.
  • Liabilities and Shareholders Equity for Q4 2025 stood at $108.4 million, up from $96.2 million in the prior quarter.
  • The five-year high for Liabilities and Shareholders Equity was $358.2 million in Q4 2022, with the low at $96.2 million in Q3 2025.
  • Historically, Liabilities and Shareholders Equity has averaged $230.2 million across 5 years, with a median of $247.3 million in 2021.
  • Annual changes were most pronounced in 2022 — Liabilities and Shareholders Equity advanced 17.32% — and 2025, when it tumbled 50.99%.
  • Karyopharm Therapeutics' Liabilities and Shareholders Equity stood at $305.3 million in 2021, then grew by 17.32% to $358.2 million in 2022, then slumped by 32.87% to $240.4 million in 2023, then sank by 31.62% to $164.4 million in 2024, then plunged by 34.06% to $108.4 million in 2025.
  • The last three Liabilities and Shareholders Equity figures came in at $108.4 million (Q4 2025), $96.2 million (Q3 2025), and $104.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Liabilities and Shareholders Equity (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 37.37 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - 811.27 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 14.93 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 1.73 Bn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 33.89 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - 23.64 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 12.81 Mn
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 26.48 Bn
9 Abivax 91.71 Bn 91.71 Bn - 640.56 Mn
10 Karyopharm Therapeutics 95.31 Mn 31.56 Mn 32.74 Mn 108.42 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 108.42 Mn
Sep 30, 2025 96.23 Mn
Jun 30, 2025 104.88 Mn
Mar 31, 2025 127.71 Mn
Dec 31, 2024 164.42 Mn
Sep 30, 2024 189.48 Mn
Jun 30, 2024 213.98 Mn
Mar 31, 2024 204.46 Mn
Dec 31, 2023 240.44 Mn
Sep 30, 2023 269.96 Mn
Jun 30, 2023 297.83 Mn
Mar 31, 2023 325.80 Mn
Dec 31, 2022 358.17 Mn
Sep 30, 2022 231.24 Mn
Jun 30, 2022 256.48 Mn
Mar 31, 2022 294.03 Mn
Dec 31, 2021 305.31 Mn
Sep 30, 2021 254.09 Mn
Jun 30, 2021 286.57 Mn
Mar 31, 2021 274.91 Mn