Karyopharm Therapeutics (KPTI) Gross Profit (2019 - 2026)
Karyopharm Therapeutics (KPTI) reported Gross Profit of $32.35 million for Q2 2026, down 12.3% from $36.88 million a year earlier.
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Karyopharm Therapeutics (KPTI) Gross Profit (2019 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Karyopharm Therapeutics' Gross Profit came in at $143.75 million, up 8.7% year-over-year; for FY2025, it was $140.12 million, up 0.6% from FY2024.
- Gross Profit has a five-year compound annual growth rate of 5.9% (FY2020 to FY2025).
- By year, Gross Profit came in at $139.23 million in FY2024 (-1.3%), $141.09 million in FY2023 (-7.1%), $151.86 million in FY2022 (-26.4%) and $206.42 million in FY2021 (+95.9%).
- The Q2 2026 figure ranks as the lowest quarterly Gross Profit since Q1 2025.
- Year over year, Gross Profit gained in three of the last seven quarters, with an average decline of 1.5%.
- The high point for year-over-year Gross Profit in five years was Q2 2022 (growth of 80.5%); the low point was Q4 2022 (a decline of 74.7%).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn |
| 10 | Karyopharm Therapeutics | 35.30 Mn | -191.12 Mn | 32.35 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 32.35 Mn |
| Dec 31, 2025 | 32.60 Mn |
| Sep 30, 2025 | 41.93 Mn |
| Jun 30, 2025 | 36.88 Mn |
| Mar 31, 2025 | 28.71 Mn |
| Dec 31, 2024 | 29.21 Mn |
| Sep 30, 2024 | 37.48 Mn |
| Jun 30, 2024 | 41.32 Mn |
| Mar 31, 2024 | 31.22 Mn |
| Dec 31, 2023 | 32.26 Mn |
| Sep 30, 2023 | 35.10 Mn |
| Jun 30, 2023 | 36.39 Mn |
| Mar 31, 2023 | 37.35 Mn |
| Dec 31, 2022 | 31.71 Mn |
| Sep 30, 2022 | 35.17 Mn |
| Jun 30, 2022 | 38.74 Mn |
| Mar 31, 2022 | 46.24 Mn |
| Dec 31, 2021 | 125.53 Mn |
| Sep 30, 2021 | 37.10 Mn |
| Jun 30, 2021 | 21.46 Mn |
API Access
Karyopharm Therapeutics Gross Profit API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-profit&ticker=KPTI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-profit", "ticker": "KPTI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-profit&ticker=KPTI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();