Based on data from the past 90 days ending February 19, 2026, Karyopharm Therapeutics's three largest insider shareholders are President And Ceo Richard A. Paulson (279.39K shares), Evp & Chief Commercial Officer Sohanya Roshan Cheng (111.92K shares), Chief Scientific Officer Sharon Shacham (111.46K shares).
| Holder | Position | Shares | Report Date |
|---|---|---|---|
| Sharon Shacham | Chief Scientific Officer | 111,465 | 31 Mar, 2022 |
| Michael Kauffman | 107,465 | 02 Mar, 2022 | |
| Michael Mason | Evp And Cfo & Treasurer | 26,072 | 05 Sep, 2024 |
| Richard A. Paulson | President And Ceo | 279,391 | 09 Feb, 2026 |
| Ran Frenkel | Evp And Chief Dev. Officer | 11,220 | 02 Mar, 2022 |
| Jatin Shah | Evp And Chief Medical Officer | 8,630 | 22 Feb, 2022 |
| Stephen Mitchener | Svp And Chief Business Officer | 8,555 | 02 Mar, 2023 |
| Sohanya Roshan Cheng | Evp & Chief Commercial Officer | 111,921 | 03 Feb, 2026 |
| Stuart Poulton | Evp And Chief Development Officer | 99,807 | 03 Feb, 2026 |
| Michael Mano | Evp And Clo&Secretary | 97,490 | 03 Feb, 2026 |
| Lori Macomber | Evp And Cfo & Treasurer | 85,105 | 04 Feb, 2026 |
| Reshma Rangwala | Evp & Chief Medical Officer | 61,805 | 03 Feb, 2026 |
| Garen G Bohlin | 3,009 | 12 Sep, 2023 | |
| Kristin Abate | Chief Accounting Officer | 22,622 | 29 Jan, 2026 |
| Barry E Greene | 907 | 15 Aug, 2022 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 05 Feb, 2026 | Richard A. Paulson | Common Stock | A | 81,060 | $0.00 | 279,391 | D | A |
| 03 Feb, 2026 | Lori Macomber | Common Stock | D | 1,626 | $6.30 | 85,105 | D | S |
| 31 Jan, 2026 | Reshma Rangwala | Common Stock | A | 32,415 | $0.00 | 61,805 | D | A |
| 31 Jan, 2026 | Michael Mano | Common Stock | A | 32,415 | $0.00 | 97,490 | D | A |
| 31 Jan, 2026 | Sohanya Roshan Cheng | Common Stock | A | 32,415 | $0.00 | 111,921 | D | A |
| 31 Jan, 2026 | Stuart Poulton | Common Stock | A | 32,415 | $0.00 | 99,807 | D | A |
| 31 Jan, 2026 | Lori Macomber | Common Stock | A | 32,415 | $0.00 | 86,731 | D | A |
| 28 Jan, 2026 | Kristin Abate | Common Stock | D | 50 | $7.03 | 22,622 | D | S |
| 27 Jan, 2026 | Kristin Abate | Common Stock | A | 92 | $0.00 | 22,672 | D | A |
| 21 Jan, 2026 | Kristin Abate | Common Stock | D | 265 | $5.96 | 22,580 | D | S |
| 15 Oct, 2025 | Richard A. Paulson | Common Stock | A | 114,285 | $0.00 | 198,331 | D | A |
| 15 Oct, 2025 | Michael Mano | Common Stock | A | 43,650 | $0.00 | 65,075 | D | A |
| 15 Oct, 2025 | Sohanya Roshan Cheng | Common Stock | A | 43,650 | $0.00 | 79,506 | D | A |
| 15 Oct, 2025 | Stuart Poulton | Common Stock | A | 39,682 | $0.00 | 67,392 | D | A |
| 15 Oct, 2025 | Lori Macomber | Common Stock | A | 43,650 | $0.00 | 54,316 | D | A |
| 15 Oct, 2025 | Kristin Abate | Common Stock | A | 12,799 | $0.00 | 22,845 | D | A |
| 01 Oct, 2025 | Kristin Abate | Common Stock | D | 362 | $6.30 | 10,046 | D | S |
| 15 Sep, 2025 | Richard A. Paulson | Common Stock | D | 1,257 | $6.43 | 84,046 | D | S |
| 15 Sep, 2025 | Reshma Rangwala | Common Stock | D | 408 | $6.43 | 29,390 | D | S |
| 15 Sep, 2025 | Reshma Rangwala | - | - | 29,390 | D |